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	<hr>
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					Charles Keown-Stoneman					<span>Biostatistician</span>
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					Courtney Truong					<span>Clinical Research Specialist</span>
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					Stephanie de Sequeira					<span>Clinical Research Specialist</span>
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					Gurpreet Lakhanpal					<span>Manager, Clinical Trials Unit</span>
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					Rekha Thomas					<span>Clinical Research Specialist</span>
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					Kevin Thorpe					<span>Head of Biostatistics</span>
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					Sorcha Mulligan					<span>Clinical Research Specialist</span>
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					Melissa Giamou					<span>Clinical Research Specialist</span>
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					Kari Ala-Leppilampi					<span>Clinical Research Specialist</span>
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					Rosane Nisenbaum					<span>Associate Scientist and Biostatistician</span>
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					Roula Raptis					<span>Clinical Research Specialist</span>
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					Agota Ferenc					<span>Clinical Research Specialist </span>
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					Courtney Truong					<span>Clinical Research Specialist</span>
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					Mercy Charles					<span>Research Coordinator </span>
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					Clara Juando-Prats					<span>Clinical Research Specialist</span>
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					Audra Stitt					<span>Manager of the Observational Epidemiology and Qualitative Research Unit</span>
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					Sahar Ehtesham					<span>Clinical Research Specialist </span>
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					Shawn Nnorom					<span>Clinical Study Assistant</span>
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					Emma Richardson					<span>Clinical Research Specialist </span>
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					Christopher Allen					<span>Clinical Research Specialist</span>
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					Bruno da Costa					<span>Associate Director, Applied Health Research Centre </span>
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					Peter Jüni					<span>Director, Applied Health Research Centre</span>
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					Kevin Thorpe					<span>Head of Biostatistics</span>
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					Rosane Nisenbaum					<span>Associate Scientist and Biostatistician</span>
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					Charles Keown-Stoneman					<span>Biostatistician</span>
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					Fei Zuo					<span>Research Biostatistician</span>
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					Gerald Lebovic					<span>Biostatistician</span>
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					Malini Handa Leno					<span>Manager, Business Operations</span>
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					Daniel Jin					<span>Business Analyst</span>
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					Joanne Roberti					<span>Administrative Assistant </span>
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						<li class="noshow" data-html="#business-operations-carrie-adams">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2020/01/DSC_3303-3-220x220.jpg" alt="" />
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					<div class="profile-title">
					Carrie Adams					<span>Business Coordinator</span>
				</div>
			</li>
					</ul>
		</div>
	<div id="team-group-8" class="team-group" style="display:none">
			<ul class="profiles">
					<li class="noshow" data-html="#research-information-systems-melissa-tom">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Melissa-T-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Melissa Tom					<span>SAS Programmer / Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-marla-campbell">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/no-photo-available-220x220.jpg" alt="" />
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					<div class="profile-title">
					Marla Campbell					<span>Research Applications Support Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-dr-maria-naydenova-md">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Maria-HUB-portraits-High-Res-10-of-75-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Maria Naydenova					<span>Senior Research Database Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-kosma-wysocki">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2017/08/Portrait-20-of-78-220x220.jpg" alt="" />
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					<div class="profile-title">
					Kosma Wysocki					<span>Manager, Research Information Systems</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-pamela-de-verno">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Pam-220x220.jpg" alt="" />
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					<div class="profile-title">
					Pamela De Verno					<span>Senior Research Database Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-bryan-boodhoo">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/no-photo-available-220x220.jpg" alt="" />
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					<div class="profile-title">
					Bryan Boodhoo					<span>Research Database Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-althea-ambosta-logan-ma">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2015/04/Althea-March-2015-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Althea Ambosta Logan					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-danny-marchese">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Danny-220x220.jpg" alt="" />
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					<div class="profile-title">
					Danny Marchese					<span>Research Database Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-alice-dang">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Portraits-LKSKI-lobby-Amanda-Francis-low-res-16-of-49-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Alice Dang					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-mohammed-hussain">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/no-photo-available-220x220.jpg" alt="" />
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					<div class="profile-title">
					Mohammed Hussain					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-brian-kirkham">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/06/Portrait-17-of-78-220x220.jpg" alt="" />
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					<div class="profile-title">
					Brian Kirkham					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-jhansi-lakshmi-saranu">
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					<div class="profile-title">
					Jhansi Lakshmi Saranu					<span>Research Data Management Specialist</span>
				</div>
			</li>
					</ul>
		</div>
	<div id="team-group-9" class="team-group" style="display:none">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Dominic-220x220.jpg" alt="" />
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					<div class="profile-title">
					Dominic Lee					<span>Research Quality Lead</span>
				</div>
			</li>
						<li class="noshow" data-html="#quality-assurance-monitoring-kaushal-pandya">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/AHRC-Portrait-49-220x220.jpg" alt="" />
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					<div class="profile-title">
					Kaushal Pandya					<span>Research Compliance & Education Specialist</span>
				</div>
			</li>
					</ul>
		</div>
	<div id="team-group-10" class="team-group" style="display:none">
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</main></div></div>
			<div style="display:none" id="all-melissa-tom">
				<div>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Melissa-T-220x220.jpg" alt="" />
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													<h2>Melissa Tom</h2>
						<h3>SAS Programmer / Research Data Management Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Melissa Tom is a SAS Programmer and Research Data Management Specialist and has been with the Research Information Systems team since December 2012. In her role at the AHRC, she is responsible for data management, data extraction and reporting of clinical data. Melissa has several years of experience using SAS.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/AHRC-Portrait-9-220x220.jpg" alt="" />
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													<h2>Gurpreet Lakhanpal</h2>
						<h3>Manager, Clinical Trials Unit</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Gurpreet Lakhanpal, MSc, CCRP, PMP is the Manager of Clinical Trials Unit overseeing a team supporting all RCTs coordinated at the AHRC. She joined the AHRC in 2018 as a Project Manager overseeing the day-to-day operations of the T1ME Trial and its sub-studies, an innovative and pragmatic program bringing virtual healthcare and support mechanisms to people living with type 1 diabetes.</p>
<p>Prior to joining the AHRC, Gurpreet worked in several leading Toronto academic hospitals, including SickKids, Mount Sinai Hospital and Sunnybrook Health Sciences Centre and the CRO start-up, Ozmosis Research Inc. Gurpreet brings a wealth of knowledge in clinical research, molecular biology, project management and research operations and administration.</p>
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													<h2>Hailey Saunders</h2>
						<h3>Health Economist</h3>
						<h5><p>Hailey Saunders received her MSc in Epidemiology &amp; Biostatistics from Western University. She has experience conducting economic analyses to show the value of health interventions or to examine their potential economic impact for interventions such as mental health and addictions programs, and cancer treatments. In her current role, she uses various methodologies and software to help create economic evidence to support decision-makers, health professionals, and researchers</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Rosane-220x220.jpg" alt="" />
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													<h2>Rosane Nisenbaum</h2>
						<h3>Associate Scientist and Biostatistician</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Dr. Rosane Nisenbaum, PhD, has special interest in multi-level models, longitudinal and categorical data analysis and multiple imputation applied to neighborhood effects on mental health, and homelessness and housing studies. She provides assistance in the design and analysis of studies conducted by St. Michael’s investigators, fellows and students and is a member of St. Michael’s Research Ethics Board. Dr. Nisenbaum is an Assistant Professor in the Division of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, co-teaching the course ‘Laboratory in Statistical Design &amp; Analysis’ and serving as a Practicum supervisor.</p>
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				</div>
			</div>
					<div style="display:none" id="all-mohammed-hussain">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/no-photo-available-220x220.jpg" alt="" />
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													<h2>Mohammed Hussain</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Mohammed Hussain is a Research Data Management Specialist in the Research Information Systems unit at the AHRC. His primary role consists of data management activities including data quality and reporting for both clinical trials and observational studies. Mohammed brings over five years of clinical research and management experience through cardiovascular research at St. Michael’s Hospital. He received an Hon BSc from the University of Toronto at St. George with a major in cell and molecular biology.</p>
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			</div>
					<div style="display:none" id="all-daniel-jin-2">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/06/AHRC-portrait-48-of-120-220x220.jpg" alt="" />
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													<h2>Daniel Jin</h2>
						<h3>Business Analyst</h3>
						<h5><p>Daniel Jin is the Business Analyst at the AHRC. He supports the leadership and project teams with business strategies and planning along with financial management. Daniel has previous experience in business and project operation in both pharmaceutical and hospital sectors. He most recently worked as a project manager in the Clinical Trials Unit at the AHRC. Daniel holds a HBSc in Biology and Psychology from the University of Toronto.</p>
</h5>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/no-photo-available-220x220.jpg" alt="" />
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													<h2>Val Panzov</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Dr. Val Panzov, MD, has more than 15 years of extensive clinical research experience as well as comprehensive clinical background. Prior to joining the Clinical Trials Unit in 2008, Dr. Panzov worked in various positions managing clinical operations, R&amp;D and business development in pharmaceutical and academic settings. As a Clinical Research Specialist, Val oversees multi-centre clinical trials and is responsible for clinical trials development in a broad range of therapeutic areas.</p>
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				</div>
			</div>
					<div style="display:none" id="all-nicole-cooke">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2019/06/AHRC-portraits-and-group_select_highres-11-220x220.jpg" alt="" />
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													<h2>Nicole Cooke</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Nicole Cooke (CCRP) is a Clinical Research Specialist within the Clinical Trials Unit. In this role, Nicole is responsible for various aspects of clinical trial management including study startup initiatives, assisting in protocol development and implementation, recruitment tracking and site-level support. With experience managing multi-center oncology trials, Nicole is familiar with central trial coordination within both academic and non-academic settings<strong><em>.</em></strong></p>
<p>&nbsp;</p>
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				</div>
			</div>
					<div style="display:none" id="all-christopher-allen">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2015/04/Chris-A-March-2015-220x220.jpg" alt="" />
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													<h2>Christopher Allen</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Christopher Allen, BSc, has both clinical and basic research experience. He has a BSc (Hons.) in Biochemistry and Molecular Biology and his graduate work is in cancer immunology. He has more than three years of clinical research experience in hematology/oncology. As a Clinical Research Specialist in the Observational Epidemiology and Qualitative Research Unit, Christopher oversees several projects. His roles involve study design and initiation, site management, development of case report forms and databases, data collection and quality control, research communications, and site reimbursement.</p>
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				</div>
			</div>
					<div style="display:none" id="all-fei-zuo">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/AHRC-Portrait-22-copy-220x220.jpg" alt="" />
		</div>
													<h2>Fei Zuo</h2>
						<h3>Research Biostatistician</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Fei Zuo, MPH, is a Research Biostatistician at the AHRC. Fei collaborates with researchers from various disciplines and provides statistical support for randomized clinical trials. Prior to joining the AHRC in 2018, Fei worked in the pharmaceutical industry as a statistical programmer, and in the provincial government as a research epidemiologist. Fei holds a Masters of Public Health in Epidemiology from the University of Toronto.</p>
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				</div>
			</div>
					<div style="display:none" id="all-prof-kevin-thorpe-mmath">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Kevin-220x220.jpg" alt="" />
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													<h2>Kevin Thorpe</h2>
						<h3>Head of Biostatistics</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Kevin Thorpe, MMath, has over 20 years of experience in clinical research as a biostatistician and methodologist. He is currently an Assistant Professor in the Dalla Lana School of Public Health at the University of Toronto and is Head of Biostatistics and a methodologist with the AHRC, where he specializes in clinical trials.</p>
					</div>
				</div>
			</div>
					<div style="display:none" id="all-carrie-adams">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2020/01/DSC_3303-3-220x220.jpg" alt="" />
		</div>
													<h2>Carrie Adams</h2>
						<h3>Business Coordinator</h3>
						<h5><p>Carrie Adams is the Business Coordinator for the AHRC who is responsible for overseeing the payroll and organization of daily operations for the team, as well as supporting the process of finance-related deliverables. Carrie holds a Bachelor of Health Administration (BHA) with distinction from Ryerson University, and is completing a Master of Health Administration (MHA) from the University of Regina. In addition, she comes to the AHRC team with over 20 years of hospital administration experience, a Lean Yellow Belt Certificate from the Leading Edge Group, and is a current member of the Canadian College of Health Leaders (CCHL).</p>
</h5>
					</div>
					<div class="bio">
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			</div>
					<div style="display:none" id="all-shawn-nnorom">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/AHRC-Portrait-77-220x220.jpg" alt="" />
		</div>
													<h2>Shawn Nnorom</h2>
						<h3>Clinical Study Assistant</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Shawn Nnorom, is a Clinical Study Assistant II with the Observational Epidemiology and Qualitative Research Unit at AHRC. He is responsible for providing support and assistance to the CSAs in their management of the multi-centered trials. Prior to working at AHRC, Shawn had worked for a number of years in the pharmaceutical/healthcare industry at various public and private institutions. Shawn holds a BSc. In Biochemistry from the University of Ottawa and a Postgraduate Certificate in Clinical Research from Humber College.</p>
					</div>
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			</div>
					<div style="display:none" id="all-kari-ala-leppilampi">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/08/Portrait-4-of-78-220x220.jpg" alt="" />
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													<h2>Kari Ala-Leppilampi</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Kari Ala-leppilampi received a Master of Planning (MPl) degree from Ryerson University’s School of Regional and Urban Planning and an MSc in Health Promotion from the Dalla Lana School of Public Health, University of Toronto. Through his graduate level training and employment in both urban planning and public health research, Kari brings a broad base of knowledge to his role at AHRC, and a uniquely valuable multidisciplinary perspective. While his specialty is qualitative inquiry, Kari is also well versed in quantitative and mixed methods approaches, and has taught courses on research theory and methods. His research has focused on a wide range of issues including outcomes associated with illicit drug policy, criminal justice diversion programs, mental health and addiction treatment services, and policies in relation to the provision of affordable and supportive housing. In keeping with his personal interest in physical activity, his research has also focused on the social benefits of active transportation, and the potential role of exercise and sport in recovery from mental health and addiction issues. As a Clinical Research Specialist, Kari focuses on qualitative, health services research by coordinating research studies, and conducting qualitative interviews and analysis on a range of health related interventions.</p>
					</div>
				</div>
			</div>
					<div style="display:none" id="all-danusha-nandamalavan">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2017/11/AHRC-portrait-63-of-120-220x220.jpg" alt="" />
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													<h2>Danusha Nandamalavan</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p><span style="font-family: Calibri; font-size: medium;">Danusha Nandamalavan, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides support in the planning and management of multi-centre randomized clinical trials. Danusha has experience working in both academic and non-academic settings, and has been involved in all types of trials. Danusha is an active member of the Society of Clinical Research Associates (SOCRA).</span></p>
<p>&nbsp;</p>
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				</div>
			</div>
					<div style="display:none" id="all-kaushal-pandya">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/AHRC-Portrait-49-220x220.jpg" alt="" />
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													<h2>Kaushal Pandya</h2>
						<h3>Research Compliance & Education Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Kaushal Pandya, B.Sc., ASQ CQA, CCRP has a background in Medical laboratory technology, Microbiology and Quality Assurance. Kaushal has over ten years of successful track records in Clinical Research Compliance as a QA Auditor and QA Specialist role in best managed CROs, in Research Institution at SickKids, where his contribution was Investigator Initiated Trial Management Team training and consultation, Regulatory Submission and Inspection Readiness, conducting Internal Audits and have hosted more than ten regulatory inspections including Health Canada and FDA.  With his recent successful track record at Novo nordisk pharmaceutical as an Inspection Readiness and GCP Specialist, Kaushal had successfully trained colleagues in Canada and across the globe on Health Canada Div. V, ICH-GCP, CAPA, where he has conducted onboarding, training and education sessions for the sponsor clinical development teams including CTMS, CRAs, and SCs. He also, developed an audit and inspection ready culture across all the organizations he has worked for.</p>
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				</div>
			</div>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/no-photo-available-220x220.jpg" alt="" />
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													<h2>Emma Richardson</h2>
						<h3>Clinical Research Specialist </h3>
						<h5><p>Dr. Emma Richardson is Applied Health Research Specialist and Assistant Professor at the Department of Health Research, Methods, Evidence and Impact at McMaster University.  Her maternal health research builds on her field experience working with the United Nations in Nicaragua, Honduras and Guatemala and internationally as a strategic planning consultant with the United Nations System Staff College.  Emma worked previously at St. Michael’s Hospital with the Centre for Ethical, Social and Cultural Risk and at the Evaluation Centre for Complex Health Interventions. She holds a Phd in Health and Behavioural Sciences from the University of Toronto, an MSc in Development Studies from the London School of Economics and a BA in Economics and International Studies, with a focus on Latin America, from the University of North Carolina at Chapel Hill.  Emma has an interest in applying realist evaluation and community engagement approaches to critical qualitative health research and strives to conduct research at the intersection with programming and policy.</p>
</h5>
					</div>
					<div class="bio">
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			</div>
					<div style="display:none" id="all-dr-maria-naydenova-md">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Maria-HUB-portraits-High-Res-10-of-75-220x220.jpg" alt="" />
		</div>
													<h2>Maria Naydenova</h2>
						<h3>Senior Research Database Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Dr. Maria Naydenova, MD, has more than 15 years of clinical research experience and a strong clinical background. She received an MD in Plovdiv Medical University, Bulgaria. As a Research Database Specialist at the AHRC, Maria is responsible for the design, build, and support of clinical studies in various electronic data capture systems. Prior to joining the Research Information Systems team in 2010, Maria worked in pharmaceutical industries and health care sectors monitoring sites and overseeing clinical trial data for national and international clinical trials.</p>
					</div>
				</div>
			</div>
					<div style="display:none" id="all-jhansi-lakshmi-saranu">
				<div>
					<div class="top-info">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/04/Jhansi-HUB-portraits-High-Res-29-of-75-220x220.jpg" alt="" />
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													<h2>Jhansi Lakshmi Saranu</h2>
						<h3>Research Data Management Specialist</h3>
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						<p>Jhansi Lakshmi Saranu, BDS, is a Certified Clinical Data Manager from the Society for Clinical Data Management with nine years of clinical data management experience. In the role of Research Data Management Specialist at the AHRC, Jhansi is responsible for development of data management plans, performing data validation activities on the electronic case report form, reviewing the data to ensure it is accurate and complete, and providing reports to sponsors and sites on validation progress. She works with the clinical team at the AHRC and also communicates with study research coordinators at sites and sponsors. Prior to joining the AHRC, Jhansi worked as a data coordinator at the Canadian Heart Research Centre, and is a dentist from NTR University of Health Sciences, India.</p>
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													<h2>Sydney Currier</h2>
						<h3>Clinical Research Spcialist</h3>
						<h5></h5>
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						<p>Sydney Currier is a clinical study assistant with the AHRC. Her previous roles have been focused on preclinical research in the field of HIV treatment, coordination of a funding program at the University of Toronto and clinical research as a member of St. Michael’s Hospital. In her current role as clinical study assistant, Sydney provides support to study project leads, assisting in the coordination of international clinical trials. She holds an Honors Bachelor of Science from the University of Toronto with a focus in Pharmaceutical Chemistry, and is currently working towards a MSc in Pharmaceutical Sciences with the Leslie Dan Faculty of Pharmacy.</p>
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													<h2>Karima Noordin</h2>
						<h3>Clinical Research Specialist </h3>
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						<p>Karima Noordin, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides administrative support in the planning and management of multi-centre randomized clinical trials. Karima has experience working in both academic and non-academic settings, and has been involved in all types of trials, including bioequivalence, phase I-IV and observational research. Karima is an active member of the Society of Clinical Research Associates (SOCRA).</p>
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													<h2>Stephanie de Sequeira</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Stephanie de Sequeira, HBSc, MPH, is a Clinical Research Specialist with the Clinical Trials Unit, and has experience in qualitative and clinical research methodologies. Stephanie is responsible for the day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and management of multi-centre randomized clinical trials. In addition, Stephanie also helps investigators with protocol development, creation of data collection tools, and manuscript preparation. Stephanie completed her HBSc in Psychology at the University of Toronto Scarborough and her Masters of Public Health at the Dalla Lana School of Public Health at the University of Toronto.</p>
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													<h2>Agota Ferenc</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
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						<p>Agota Ferenc, MSc, ACRP-CP is a Clinical Research Specialist with the Observational Epidemiology &amp; Qualitative Research team and is responsible for the day-to-day project management of various clinical studies. Agota oversees clinical operations activities from study start-up to close-out including but not limited to: protocol development; research ethics submission; electronic case report form creation; essential document creation; trial master file (TMF) maintenance; and the management of study budgets, payments and contracts. Prior to joining AHRC, she worked in the CRO industry. She holds a Master of Science in Human Health from the University of Guelph and a Clinical Research Graduate Certificate from Seneca College. Agota is an active member of the Association of Clinical Research Professionals (ACRP).</p>
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													<h2>Deena</h2>
						<h3>Research Assistant</h3>
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						<p>Deena, M.B.B.S., is a Research Assistant at the CLEAR. Her role encompasses taking care of the administrative processes of the organization and assisting the Principal Investigator with ongoing research activities including the submissions of REB applications, grants, and manuscripts, conducting literature reviews, and performing data analyses. She recently completed the Internationally Trained Medical Doctors (ITMD) Bridging Program at Ryerson University, where she gained exposure in Health Informatics, Communication and Leadership skills, Research Methodologies, and Project Management. As an internationally trained medical graduate, she has a strong clinical background from her experience working in the Family Medicine and Community Health fields.</p>
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													<h2>Ben Markowitz</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
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						<p>Ben Markowitz completed his BSc (Hons) in Kinesiology from the University of Western Ontario, and received an MSc from the Institute of Medical Science at the University of Toronto. Ben joins the AHRC with experience conducting qualitative health research at St. Michael’s Hospital and Women’s College Hospital. As a Master’s student, Ben used a narrative methodology to assess transitions from pediatric into adult diabetes care. For his prior research, Ben was honoured with a Queen Elizabeth II Graduate Scholarship in Science and Technology. Ben has also published research in the Canadian Journal of Diabetes and presented original findings at the American Diabetes Association’s Scientific Sessions. As a Clinical Research Specialist at the AHRC, Ben continues to pursue his interest in using qualitative inquiry to positively impact health services.</p>
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													<h2>Audra Stitt</h2>
						<h3>Manager of the Observational Epidemiology and Qualitative Research Unit</h3>
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						<p>Audra Stitt, MSc is the Manager of the Observational Epidemiology and Qualitative Research Unit of the AHRC. Audra brings more than 17 years of experience with public health research, population and cohort based observation studies and clinical trials and has been managing research teams since 2010. She has extensive experience with data abstraction (in both prehospital and hospital settings), large administrative data sets, project management, and education. Audra is responsible for the oversight of observational and qualitative research studies as well as the planning and operations of patient registries.</p>
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													<h2>Danny Marchese</h2>
						<h3>Research Database Specialist </h3>
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						<p>Danny Marchese has been working with St. Michael’s Hospital since June of 2000, previously in the role of Technical Support Specialist, Information Technology. He has been working with the Research Information Systems team at the AHRC since June 2012 and is responsible for design and creation of electronic case report forms used for capturing clinical trial study data.</p>
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													<h2>Sahar Ehtesham</h2>
						<h3>Clinical Research Specialist </h3>
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						<p>Sahar is working as a Clinical Research Specialist in Observational Epidemiology and Qualitative Research Unit. She is responsible for managing multi-site studies from the coordinating centre.</p>
<p>&nbsp;</p>
<p>Sahar has over 14 years of experience working in Clinical Research on investigator initiated as well as industry sponsored studies.  She has been involved in conducting day to day tasks for observational studies.  Additionally, Sahar has managed multi-site national observational studies and multi-site international clinical trials.  Through the various roles Sahar has held, she has had the opportunity to contribute to every aspect and stage of clinical research including, assisting in drafting study protocols, grant applications and manuscripts, completing regulatory and ethical applications, formulating budgets, initiating study sites, data management and analysis.</p>
<p>&nbsp;</p>
<p>Sahar has received HBSc in Cell and Molecular Biology from University of Toronto and MSc in Health Research Methodology from McMaster University.  she has also completed a Clinical Research Associate program at Michener Institute.  Sahar authored several manuscripts that have been published in peer reviewed journals. she has also authored and presented posters at conferences.</p>
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													<h2>Malini Handa Leno</h2>
						<h3>Manager, Business Operations</h3>
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						<p>Malini Handa Leno, MSc, MBA, PMP, is the Manager, Business Operations, and is accountable for financial, human resource, and contract management at the AHRC. Malini joined the AHRC with 15 years of experience in the pharmaceutical, CRO, and hospital sectors. Her previous roles have focused on clinical trial management, patient safety and risk management, and most recently, the implementation of information management systems to help transform health care. Malini holds an MBA from the Desautels Faculty of Management at McGill University, and an MSc in Pharmacology from Dalhousie University.</p>
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													<h2>Tiffany Jefkins</h2>
						<h3>Clinical Research Specialist </h3>
						<h5><p>Tiffany Jefkins, PhD(c), is a Clinical Research Specialist with OEQRU at AHRC. Tiffany specializes in data management, project planning and coordination of studies in the prehospital setting. She is currently working with C-SCAN (Canadian Sudden Cardiac Arrest Network) registry, a collaboration between the Cardiac Arrhythmia Network of Canada (CANet) and the Canadian Resuscitation Outcomes Consortium (CanROC). Prior to joining the AHRC, Tiffany worked for six years as a Respiratory Therapist in Critical Care. She is currently a doctoral student at the University of Toronto – Institute of Health Policy, Management and evaluation – Health services Research where she is focusing on lay responder experiences during an out-of-hospital cardiac arrest.</p>
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													<h2>Farzaana Ali</h2>
						<h3>Clinical Research Specialist </h3>
						<h5><p>Farzaana Ali, HBSc, CCRA, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and management of multi-centre randomized clinical trials. Farzaana completed her HBSc in Biology, Psychology and English from the University of Toronto and obtained her Post-Graduate Certificate in Clinical Research from Humber College. She has five years of previous experience working in various research environments, including: academic, clinical research IT, hospital (pediatric oncology) and a Phase I contract research organization.</p>
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													<h2>Joanne Roberti</h2>
						<h3>Administrative Assistant </h3>
						<h5><p>Joanne Roberti is the Administrative Assistant to Dr. Peter Jüni, the Director AHRC, working closely with him to provide personalized support of his (as well as departmental and hospital) goals and objectives. She is the administrative point of contact between the Director, AHRC and the AHRC staff, internal partners, and external clients.</p>
<p>Joanne has a BA from the University of Toronto, and a well-rounded portfolio of administrative skills with over 20 years of experience in research and education sectors. Prior to joining  the AHRC , she worked for 10 years at The Centre for Phenogenomics, a research facility owned and operated by Mount Sinai Hospital and The Hospital for Sick Children, where she provided a wide variety of administrative and project support, including event planning to a Senior Associate Scientist /Director of Research Partnerships, and Service Cores staff.</p>
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													<h2>Sorcha Mulligan</h2>
						<h3>Clinical Research Specialist</h3>
						<h5><p>Sorcha is a Clinical Research Specialist with the Clinical Trials Unit. She is responsible for the daily project management of a number of international multi-centre trials, including preparing documentation and regulatory submissions, site set-up and training, recruitment monitoring and supply management.</p>
<p>Before joining the AHRC, Sorcha spent over six years at the University of Oxford’s Clinical Trials Service Unit (CTSU) at the Nuffield Department of Population Health (NDPH). She worked as a Clinical Trial Manager on large-scale international renal and cardiovascular trials. Prior to this, Sorcha worked in the NDPH Wolfson Laboratories as a Scientific Officer and Laboratory Training Officer, on large observational studies and randomised trials. She completed a bachelors’ degree in Physiology at Trinity College, Dublin.</p>
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													<h2>Alice Dang</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
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						<p>Alice Dang holds a BSc in Pharmaceutical Chemistry from the University of Toronto. She joined the AHRC in 2012 as a Professional Experiential Year (PEY) intern in the role of Research Assistant, and returned full-time as a Clinical Study Assistant after the completion of her degree in 2014. Now in the role of Research Data Management Specialist, Alice is responsible for reviewing the data of a large multi-centre trial to ensure it is complete and accurate, and also provides support to project managers in the Clinical Trials Unit.</p>
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													<h2>Melissa Giamou</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Melissa Giamou has a BSc (Hons.) in Biology from the University of Western Ontario, and joined AHRC in 2013 through an internship for a Postgraduate Diploma in Clinical Trials Management. Melissa oversees multi-centre randomized clinical trials, particularly in the therapeutic areas of cardiology and medical devices. In her role as a Clinical Research Specialist, Melissa coordinates electronic case report form development, oversees data collection and safety reporting, creates and maintains essential project documents, helps manage study budgets, payments and contracts, along with conducting other operational activities.</p>
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													<h2>Kosma Wysocki</h2>
						<h3>Manager, Research Information Systems</h3>
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						<p>Kosma Wysocki, B.Sc. Supports the AHRC’s applications through regular system and database administration and maintenance activities as well as performing custom development work as required. Kosma brings over five years of experience in technical support and systems administration experience to the AHRC.</p>
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													<h2>Cheryl Pritlove</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Cheryl Pritlove, PhD, is a Clinical Research Specialist, employing qualitative methods to the study of a variety of health-related research topics, including cardiac health and diabetes. She has extensive experience and expertise in qualitative and arts-based methods, health policy, and psychosocial oncology. Cheryl has a BA in Health and Society and an MSc in Kinesiology and Health Science from York University. She conducted her doctoral research at the Princess Margaret Cancer Centre where she worked with patients as well as health care and service providers to identify gaps in the delivery of cancer care and explored innovative approaches to (acute/chronic) care integration.  She has conducted health services research with a number of organizations including Wellspring, ELLICSR Health, Wellness and Cancer Survivorship Centre, as well as the University of Toronto and York University.</p>
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													<h2>Jessica Marchese</h2>
						<h3>Clinical Research Specialist </h3>
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						<p>Jessica Marchese, BSc, joined the AHRC&#8217;s CTU team as a Clinical Study Assistant II in July 2017. Jessica received her BSc from the University of Toronto, focusing on human biology and physiology. She also completed a post-graduate Clinical Research Certificate Program from the Michener Institute. She has previous experience in coordinating surgical oncology clinical trails, as well as qualitative studies. At AHRC, Jessica utilizes her previous experience in order to support project managers with the day-to-day management of clinical trials and general study administrative support.</p>
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<p><span style="font-family: 'Calibri Light','sans-serif'; font-size: 10.5pt;"><span style="color: #000000;"> </span></span></p>
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													<h2>Althea Ambosta Logan</h2>
						<h3>Research Data Management Specialist</h3>
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						<p><span style="font-family: Calibri; font-size: medium;">Althea Ambosta Logan, M.A., CCRP, is a Data Management Specialist with the Research Information Systems team at the AHRC. Althea is responsible for reviewing data from multi-centre clinical trials and observational studies in Medidata RAVE and REDCap, with the goal of ensuring a high level of data quality. Althea is also involved in creating data management plans, performing validation activities on electronic case report forms and generating data management reports. Prior to her current role, Althea was a Clinical Research Specialist at the AHRC and was involved in the management and day-to-day operations of several multi-centre observational research studies. Althea holds a B.A. in Psychology from York University and an M.A. in Psychology (Brain and Cognitive Science Program) from the University of Manitoba. </span></p>
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													<h2>Janet Parsons</h2>
						<h3>Scientist</h3>
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						<p>Dr. Janet Parsons, PhD, is a Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital with expertise in qualitative research methods. Dr. Parsons specializes in visual and narrative methods, and is engaged in a program of film-based research. Additional research interests include health equity, oncology, knowledge translation, and health services research. A physiotherapist, Dr. Parsons practiced for 18 years in acute-care teaching hospitals and is cross-appointed to the Department of Physical Therapy, University of Toronto.</p>
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													<h2>Dominic Lee</h2>
						<h3>Research Quality Lead</h3>
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						<p>Dominic Lee is the Research Quality Lead at the AHRC, responsible for leading the Research Quality &amp; Process team to ensure appropriate quality and privacy controls are developed, implemented and maintained in all the AHRC&#8217;s clinical research activities. He completed the Clinical Research postgraduate program from the Michener Institute and started at the AHRC as a volunteer in 2012. Dominic has extensive project management experience in planning, executing and delivering phase II-III multi-centre, international clinical trials in accordance with ICH-GCP, TCPS2 and applicable regulations from protocol development to publication. Dominic is an active member of the Society of Clinical Research Associates (SOCRA) and a certified Project Management Professional (PMP).</p>
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													<h2>Rekha Thomas</h2>
						<h3>Clinical Research Specialist</h3>
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						<p>Rekha Thomas is a Clinical Research Specialist II with the Clinical Trials Unit at AHRC, responsible for the day to day management of the clinical trial.  In her role, she provides support in the planning and management of multi-center randomized clinical trials in various aspects including regulatory submissions, study startup initiatives, site communications, study operations, supply management.</p>
<p>Rekha has vast experience working on Phase I-II trials, Public health projects on alcohol and drug addictions and Community engagement trials on opioid overdose. Rekha also carries experience in setting up the infrastructure and processes of a Research Ethics Office in academic setting.</p>
<p>Rekha completed her Honors in Cell &amp; Molecular Biology from the University of Toronto followed by Post-Graduation in Clinical Research from Humber College. Rekha is an active member of the SOCRA since 2009.</p>
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													<h2>Ashna Jinah</h2>
						<h3>Health Economist</h3>
						<h5><p>Ashna Jinah received her MSc in Epidemiology &amp; Biostatistics from the Schulich School of Medicine &amp; Dentistry at Western University. She has obtained work experience in public health and clinical research settings. Her research interests include the epidemiology of chronic and infectious disease, health economics, global public health, health services outcomes and evaluation, and knowledge translation. At CLEAR, Ashna will be applying her knowledge and expertise gained from her multidisciplinary background and collaborating with stakeholders in health care to improve the efficiency of our system.</p>
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													<h2>Samantha Saes</h2>
						<h3>Clinical Research Specialist </h3>
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						<p>Samantha Saes, HBSc, is a Clinical Research Specialist II with the Clinical Trials Unit and is responsible for the day-to-day management of multi-centre randomized clinical trials. Her responsibilities include protocol and eCRF development, site selection and management, regulatory and ethics submissions, overseeing data collection and safety reporting, and drug supply management. Prior to joining the AHRC, Samantha worked in the pharmaceutical industry for 10 years, where she gained experience in both the operational and monitoring aspects of clinical trials (phases II-IV). She has also participated in numerous audits and inspections, and has also lead many process improvement projects. Samantha completed her BSc (Hons.) in Biological Science and Nutritional Sciences at the University of Guelph and holds a certificate from the CRA &amp; CRC Program from Barnett Educational Services.</p>
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													<h2>Clara Juando-Prats</h2>
						<h3>Clinical Research Specialist</h3>
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						<p>Clara Juando-Prats, PhD, MSc, BScN, is a Clinical Research Specialist at the AHRC. She completed her PhD at Faculty of Nursing in the University of Toronto, her MSc at the University of Edinburgh (UK), and the BScN at the Autonomous University of Barcelona (Spain). Clara uses visual methods and critical social theory to study access and utilization to the health care resources by vulnerable populations in Toronto. Her work with young mothers with low resources, young parents living in the margins, and in partnership with community agencies, aims to positively impact the physical and mental health of this population while giving them social connections with health care providers. Prior to joining the HUB, Clara was the leader of the Knowledge Translation and Nursing Research Unit at the Hospital Sant Pau in Barcelona, developing and evaluating projects studies related to clinical safety, knowledge translation, and nursing leadership. At the Hospital Sant Pau, Clara also worked as a nurse, a research nurse, and as an specialist in qualitative methods at the Epidemiology Department. She has been collaborating for several years with the Cochrane Collaboration and the Joanna Briggs Institute as an instructor and reviewer. During 2013 and 2012 she completed two fellowships, at the Spanish Ministry of Health in qualitative research with marginalized women, and at the Centre for Global Health at the University of Ottawa in Complex Interventions and Knowledge Mobilization. The focus of Clara’s work at the AHRC has been evaluation of complex interventions, qualitative and mixed methods designs for health research, knowledge translation and health inequities.</p>
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													<h2>Peter Jüni</h2>
						<h3>Director, Applied Health Research Centre</h3>
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						<p>Peter is the Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, holds a Tier 1 Canada Research Chair in Clinical Epidemiology of Chronic Diseases, and is a Professor at the Department of Medicine and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He is a graduate of the Faculty of Medicine at the University of Bern in Switzerland, completed his training in internal medicine at various hospitals in Switzerland, and was a Research Fellow at the Department of Social Medicine at the University of Bristol, UK. Prior to joining St. Michael’s Hospital, Peter was the Director of the Institute of Primary Health Care and Professor of Primary Care and Clinical Epidemiology at the Faculty of Medicine at the University of Bern in Switzerland. He held previous appointments as Director of the Institute of Social and Preventive Medicine at the University of Bern and Founding Director of CTU Bern, the University’s clinical trials unit.</p>
<p>Peter is internationally renowned for his methodological work and for his clinical research on the management of cardiovascular and musculoskeletal disorders. A Fellow of the European Society of Cardiology, he has had leading roles in several major cardiovascular trials, including SIRTAX, LEADERS, FAME 2 and MATRIX, served as a member of several task forces of the European Society of Cardiology and co-authored the European guidelines on myocardial revascularization and on the management of acute myocardial infarction. Peter contributed to over 400 papers, which were cited more than 80,000 times. Since 2015 he was been recognized as <a href="https://recognition.webofsciencegroup.com/awards/highly-cited/2019/">Highly Cited Researcher</a>.</p>
<p>PUBLICATIONS:</p>
<ol>
<li>Iglesias JF, Muller O, Heg D, Roffi M, Kurz DJ, Moarof I, Weilenmann D, Kaiser C, Tapponnier M, Stortecky S, Losdat S, Eeckhout E, Valgimigli M, Odutayo A, Zwahlen M, Jüni P, Windecker S, Pilgrim T. Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients with ST-segment elevation myocardial infarction (BIOSTEMI): a single-blind, prospective, randomised superiority trial. Lancet. 2019 Oct 5;394(10205):1243-1253. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31488372">31488372</a>.</li>
<li>Fervenza FC, Appel GB, Barbour SJ, Rovin BH, Lafayette RA, Aslam N, Jefferson JA, Gipson PE, Rizk DV, Sedor JR, Simon JF, McCarthy ET, Brenchley P, Sethi S, Avila-Casado C, Beanlands H, Lieske JC, Philibert D, Li T, Thomas LF, Green DF, Juncos LA, Beara-Lasic L, Blumenthal SS, Sussman AN, Erickson SB, Hladunewich M, Canetta PA, Hebert LA, Leung N, Radhakrishnan J, Reich HN, Parikh SV, Gipson DS, Lee DK, da Costa BR, Jüni P,* Cattran DC.* Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy. N Engl J Med. 2019 Jul 4;381(1):36-46. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31269364">31269364</a>.</li>
<li>Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med. 2018 Sep 27;379(13):1224-1233. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30146969">30146969</a>.</li>
<li>Vranckx P,* Valgimigli M,* Jüni P,* Hamm C, Steg PG, Heg D, van Es GA, McFadden EP, Onuma Y, van Meijeren C, Chichareon P, Benit E, Möllmann H, Janssens L, Ferrario M, Moschovitis A, Zurakowski A, Dominici M, Van Geuns RJ, Huber K, Slagboom T, Serruys PW, Windecker S. Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial. Lancet. 2018 Sep 15;392(10151):940-949. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30166073">30166073</a>.</li>
<li>Valgimigli M, Frigoli E, Leonardi S, Vranckx P, Rothenbühler M, Tebaldi M, Varbella F, Calabrò P, Garducci S, Rubartelli P, Briguori C, Andó G, Ferrario M, Limbruno U, Garbo R, Sganzerla P, Russo F, Nazzaro M, Lupi A, Cortese B, Ausiello A, Ierna S, Esposito G, Ferrante G, Santarelli A, Sardella G, de Cesare N, Tosi P, van &#8216;t Hof A, Omerovic E, Brugaletta S, Windecker S, Heg D, Jüni P. Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial. Lancet. 2018 Sep 8;392(10150):835-848. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30153988">30153988</a>.</li>
<li>Xaplanteris P, Fournier S, Pijls NHJ, Fearon WF, Barbato E, Tonino PAL, Engstrøm T, Kääb S, Dambrink JH, Rioufol G, Toth GG, Piroth Z, Witt N, Fröbert O, Kala P, Linke A, Jagic N, Mates M, Mavromatis K, Samady H, Irimpen A, Oldroyd K, Campo G, Rothenbühler M, Jüni P,* De Bruyne B.* Five-Year Outcomes with PCI Guided by Fractional Flow Reserve. N Engl J Med. 2018 Jul 19;379(3):250-259. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/29785878">29785878</a>.</li>
<li>da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, Jüni P, Trelle S. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Lancet. 2017 Jul 8;390(10090):e21-e33. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/28699595">28699595</a>.</li>
<li>Valgimigli M, Gagnor A, Calabró P, Frigoli E, Leonardi S, Zaro T, Rubartelli P, Briguori C, Andò G, Repetto A, Limbruno U, Cortese B, Sganzerla P, Lupi A, Galli M, Colangelo S, Ierna S, Ausiello A, Presbitero P, Sardella G, Varbella F, Esposito G, Santarelli A, Tresoldi S, Nazzaro M, Zingarelli A, de Cesare N, Rigattieri S, Tosi P, Palmieri C, Brugaletta S, Rao SV, Heg D, Rothenbühler M, Vranckx P, <u>Jüni P</u>. Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial. <strong>Lancet</strong>. 2015 Jun 20. 385(9986): 2465-76. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25791214">25791214</a>.</li>
<li>Biller-Andorno N, <u>Jüni P</u>. Abolishing mammography screening programs? A view from the Swiss Medical Board. <strong>N Engl J Med</strong>. 2014 May 22. 370(21): 1965-7. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/24738641">24738641</a>.</li>
<li>De Bruyne B, Fearon WF, Pijls NH, Barbato E, Tonino P, Piroth Z, Jagic N, Mobius-Winckler S, Rioufol G, Witt N, Kala P, MacCarthy P, Engström T, Oldroyd K, Mavromatis K, Manoharan G, Verlee P, Frobert O, Curzen N, Johnson JB, Limacher A, Nüesch E, <u>Jüni P</u>. Fractional flow reserve-guided PCI for stable coronary artery disease. <strong>N Engl J Med</strong>. 2014 Sep 25. 371(13):1208-17. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25176289">25176289</a>.</li>
<li>Stefanini GG, Kalesan B, Serruys PW, Heg D, Buszman P, Linke A, Ischinger T, Klauss V, Eberli F, Wijns W, Morice MC, Di Mario C, Corti R, Antoni D, Sohn HY, Eerdmans P, van Es GA, Meier B, Windecker S, <u>Jüni P</u>. Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. <strong>Lancet</strong>. 2011 Dec 3. 378(9807):1940-8. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/22075451">22075451</a>.</li>
<li>Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, Egger M, <u>Jüni P</u>. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. <strong>BMJ</strong>. 2011 Jan 11. 342: 342:c7086. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/21224324">21224324</a>.</li>
<li>Nüesch E, Trelle S, Reichenbach S, Rutjes AW, Tschannen B, Altman DG, Egger M, <u>Jüni P</u>. Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study. <strong>BMJ</strong>. 2010 Jul 16. 341:c3515. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20639294">20639294</a>.</li>
<li>Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schömig A, Pfisterer ME, Stone GW, Leon MB, Suarez de Lezo J, Goy JJ, Park SJ, Sabaté M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, <u>Jüni P</u>. Outcomes associated with drug-eluting and bare-metal stents: A collaborative network meta-analysis. <strong>Lancet</strong>. 2007 Sep 15. 370(9591):937–48. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17869634">17869634</a>.</li>
<li>Reichenbach S, Sterchi R, Scherer M, Trelle S, Bürgi E, Bürgi U, Dieppe P, <u>Jüni P</u>. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. <strong>Ann Intern Med</strong>. 2007 Apr 17. 146(8):580-90. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17438317">17438317</a>.</li>
<li><u>Jüni P</u>, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. <strong>Lancet</strong>. 2004 Dec 4-10. 364(9450):2021-9. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/15582059">15582059</a>.</li>
<li><u>Jüni P</u>, Altman DG, Egger M. Assessing the quality of controlled clinical trials. <strong>BMJ</strong>. 2001 Jul 7. 323(7303):42-6. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/11440947">11440947</a>.</li>
<li><u>Jüni P</u>, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. <strong>JAMA</strong>. 1999 Sep 15. 282(11):1054-60. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/10493204">10493204</a>.</li>
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<p><strong>AFFILIATIONS &amp; OTHER ACTIVITIES</strong></p>
<ul>
<li>Director, Applied Health Research Centre</li>
<li>Professor, Department of Medicine, University of Toronto</li>
<li>Professor, Institute of Health Policy, Management and Evaluation, University of Toronto</li>
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													<h2>Roula Raptis</h2>
						<h3>Clinical Research Specialist</h3>
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						<p>Roula (Stavroula) Raptis, MSc, has a diverse research background and interests, lending well to her analytical skills and ability to work with multi-disciplinary teams. Roula completed her BSc at the University of Waterloo, with a focus in cell and molecular biology and microbiology. She went on to complete an MSc degree at the University of Toronto in the Department of Laboratory Medicine and Pathobiology. There she explored gene polymorphisms in cancer susceptibility genes and was a member of a large, nationally funded initiative &#8211; the interprovincial Colorectal Cancer Interdisciplinary Health Research Team. Roula has experience in both academic and nonacademic settings, including working for an independent analytical laboratory for several years, as well as in various teaching environments. In her current role with the Observational Epidemiology and Qualitative Research Unit, Roula is involved in study design, patient registry and database design, protocol and data collection form development, study planning and operations, and research communications. She is the author of a book chapter on genetic instability, and an author and co-author on several additional peer-reviewed publications.</p>
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													<h2>Ori Rotstein</h2>
						<h3>Vice President of Research and Innovation</h3>
						<h5><p>Dr. Ori Rotstein is the Vice President of Research and Innovation at Unity Health Toronto. He is also a Professor and Associate Chair of the Department of Surgery at the University of Toronto.</p>
<p>In addition to his role as VP, Dr. Rotstein is a practicing General Surgeon, and is an acknowledged expert in the management of intra-abdominal infection and inflammation. He is the former Director of the Institute of Medical Science, University of Toronto, the postgraduate arm of the Faculty of Medicine at the University of Toronto from 2001-2011 that was responsible for graduate training programs for more than 500 MSc/PhD students. In 2012, the Institute of Medical Science honoured him with an annual lecture ‘The Ori D. Rotstein Lectureship in Translational Research’. He is a member of several prestigious medical societies including the Canadian Academy of Health Sciences, the American Surgical Association, and the American Society for Clinical Investigation. He is a Past President of the Surgical Infection Society and has contributed significantly to the activities of the American College of Surgeons through his participation on the Program Committee, Surgical Forum Committee, and the Scholarship Executive Committee.</p>
<p><strong>Research Interests</strong></p>
<p>Dr. Rotstein has a major interest in understanding how traumatic injury leads to alterations in the immune response of patients. He uses his clinical insights into the mechanisms of disease to generate novel therapeutic approaches to preventing poor outcome in these patients. His work spans the “bench to bedside” continuum, wherein he investigates cellular and animal models with a view to translating these to novel therapies in humans. This translational research has led to the investigation of the use of additives in resuscitation fluids in patients sustaining such injuries.</p>
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													<h2>Charles Keown-Stoneman</h2>
						<h3>Biostatistician</h3>
						<h5><p>Dr. Charlie Keown-Stoneman, received his PhD and MSc in Applied Statistics and BSc in Biological Science from the University of Guelph. Charlie has experience teaching undergraduate statistics courses at the University of Guelph as a sessional lecturer, and providing statistical consulting for the Mood Disorder Centre of Ottawa at the University of Ottawa Health Services. In his current role at the AHRC, Charlie provides statistical analysis and support for observational studies and randomized trials, primarily using R and SAS. His research interests include survival analysis, multi-state models, and longitudinal data analysis.</p>
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													<h2>Pamela De Verno</h2>
						<h3>Senior Research Database Specialist </h3>
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						<p>Pamela De Verno, MSc, has over 15 years of clinical research experience, as well as extensive experience in biotechnology research and development. As a Research Database Specialist with the Research Information Systems team, Pamela is responsible for the design, build and support of studies within a data management system for storage, validation and retrieval of clinical data.</p>
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													<h2>Lisa Masucci</h2>
						<h3>Health Economist</h3>
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						<p>Lisa Masucci received her MSc in Health Services Research from the Institute of Health Policy, Management and Evaluation at the University of Toronto, specializing in health outcomes and evaluation. She has experience in conducting cost-effectiveness and budget impact analyses for both research and decision-making settings. She previously conducted economic analyses for the Ontario Health Technology Advisory Committee (OHTAC) and Vancouver Coastal Health. Her research interests include health technology assessment, health services outcomes and evaluation, health care priority setting and knowledge translation.</p>
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													<h2>Mercy Charles</h2>
						<h3>Research Coordinator </h3>
						<h5><p>Mercy Charles is a certified Clinical Research Professional (CCRP) with 12 years of clinical research experience in various roles working in a wide range of Phase I-Phase II studies for Clinical Research Organizations (CRO). Mercy completed her Bachelors of Science (BSc.) in Applied Chemistry and Biology from Ryerson University and has obtained a Clinical Research Graduate Certificate from the Michener Institute. She is an active member of the Society of Clinical Research Associate (SOCRA) and has maintained her certification as a Clinical Research Professional since 2008. Currently, Mercy is working at the Applied Health Research Centre (AHRC) as a Research Coordinator III. She is responsible for day-to-day management of The Surviving Opioid Overdose with Naloxone Education and Resuscitation (SOONER) Project.</p>
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													<h2>Courtney Truong</h2>
						<h3>Clinical Research Specialist</h3>
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						<p>Courtney Truong, HBSc, AEMCA is a Clinical Research Specialist with OEQRU. Courtney specializes in data management, coordination of registries, and observational studies/clinical trials in the prehospital setting. She is currently working on the R3 (local) and CanROC (national) projects which are registries looking at out-of-hospital cardiac arrests and traumatic cardiac arrests.</p>
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													<h2>Bruno da Costa</h2>
						<h3>Associate Director, Applied Health Research Centre </h3>
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						<p>Dr. Bruno R. da Costa is the Associate Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute at St. Michael&#8217;s Hospital, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation of the University of Toronto. Dr. da Costa has a PhD in Clinical Epidemiology and Biostatistics from the University of Bern (Switzerland) and Master of Science degrees in Medical Statistics from the University of Leicester (UK) and in Physical Therapy from the University of Alberta (Canada). Before joining the AHRC, Dr. da Costa was the Head of Statistics and Methodology of the Department of Cardiology as well as the Head of Clinical Research of the Institute of Primary Health Care, both at the University of Bern. Previous appointments include Assistant Professor at the Department of Physical Therapy, and Adjunct Professor at the Department of Health Policy &amp; Management, both at Florida International University.</p>
<p>&nbsp;</p>
<p>Dr. da Costa has published over seventy peer-reviewed articles and is known for his clinical research on musculoskeletal and cardiovascular conditions and for his methodological research on comparative effectiveness</p>
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													<h2>Gerald Lebovic</h2>
						<h3>Biostatistician</h3>
						<h5></h5>
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						<p>Dr. Gerald Lebovic received an MSc in Statistics and a PhD in Biostatistics from the University of Toronto. He has 10 years of experience working on observational studies and has consulted on a variety of studies in the medical field. Currently, Gerald is a biostatistician at the HUB and an Assistant Professor at the Institute of Health Policy, Management and Evaluation at the University of Toronto. Gerald works with numerous researchers from various disciplines on a variety of observational studies. His research interests include health services research, longitudinal data analysis, observational studies and multi-state models.</p>
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													<h2>Marla Campbell</h2>
						<h3>Research Applications Support Specialist</h3>
						<h5><p>Marla joined the Research Information Systems team as a Research Applications Support Specialist in July of 2019.  Her role at the AHRC includes server and database administration activities in addition to custom development work.  Marla has over 10 years of experience providing technical solutions and holds a B.S. in Computer and Information Science.</p>
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													<h2>Brian Kirkham</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
					</div>
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						<p>Brian Kirkham, MSc, joined the Research Information Systems team as a Research Data Management Specialist in June 2016. His role at the AHRC includes both database development and research data management. Brian received his BSc and MSc in Medical Physics from Ryerson University. Prior to joining the AHRC, Brian spent two years working with the research team at the St. Michael’s Hospital Head Injury Clinic.</p>
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													<h2>Desmond Loong</h2>
						<h3>Health Economist</h3>
						<h5></h5>
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						<p>Desmond Loong holds an MSc in Health Services Research from the University of Toronto’s Institute of Health Policy, Management and Evaluation (IHPME).  Specializing in health outcomes and evaluation, Desmond has experience conducting economic evaluations using person-level data – as well as experience in mental health services research, program evaluations, systematic literature reviews, database management, and data analysis using STATA and SPSS. Desmond’s current focus is working with decision-makers and clinical researchers to evaluate and show the value of interventions.</p>
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													<h2>Bryan Boodhoo</h2>
						<h3>Research Database Specialist </h3>
						<h5></h5>
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						<p>Bryan Boodhoo, MSc, has more than 20 years of clinical trials research experience, predominantly in the pharmaceutical industry. He works with the Research Information Systems team as an expert in Clinical Data Programming with thorough technical understanding in the design, setup and validation of databases, creating edit checks, data extraction and transformation, and generating formatted reports and listings using SAS, RAVE, Oracle Clinical or INFORM.</p>
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											<h2>Kosma Wysocki</h2>
					<h3>Manager, Research Information Systems</h3>
					<h5></h5>
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						<p>Kosma Wysocki, B.Sc. Supports the AHRC’s applications through regular system and database administration and maintenance activities as well as performing custom development work as required. Kosma brings over five years of experience in technical support and systems administration experience to the AHRC.</p>
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											<h2>Malini Handa Leno</h2>
					<h3>Manager, Business Operations</h3>
					<h5></h5>
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						<p>Malini Handa Leno, MSc, MBA, PMP, is the Manager, Business Operations, and is accountable for financial, human resource, and contract management at the AHRC. Malini joined the AHRC with 15 years of experience in the pharmaceutical, CRO, and hospital sectors. Her previous roles have focused on clinical trial management, patient safety and risk management, and most recently, the implementation of information management systems to help transform health care. Malini holds an MBA from the Desautels Faculty of Management at McGill University, and an MSc in Pharmacology from Dalhousie University.</p>
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											<h2>Audra Stitt</h2>
					<h3>Manager of the Observational Epidemiology and Qualitative Research Unit</h3>
					<h5></h5>
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						<p>Audra Stitt, MSc is the Manager of the Observational Epidemiology and Qualitative Research Unit of the AHRC. Audra brings more than 17 years of experience with public health research, population and cohort based observation studies and clinical trials and has been managing research teams since 2010. She has extensive experience with data abstraction (in both prehospital and hospital settings), large administrative data sets, project management, and education. Audra is responsible for the oversight of observational and qualitative research studies as well as the planning and operations of patient registries.</p>
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											<h2>Peter Jüni</h2>
					<h3>Director, Applied Health Research Centre</h3>
					<h5></h5>
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						<p>Peter is the Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, holds a Tier 1 Canada Research Chair in Clinical Epidemiology of Chronic Diseases, and is a Professor at the Department of Medicine and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He is a graduate of the Faculty of Medicine at the University of Bern in Switzerland, completed his training in internal medicine at various hospitals in Switzerland, and was a Research Fellow at the Department of Social Medicine at the University of Bristol, UK. Prior to joining St. Michael’s Hospital, Peter was the Director of the Institute of Primary Health Care and Professor of Primary Care and Clinical Epidemiology at the Faculty of Medicine at the University of Bern in Switzerland. He held previous appointments as Director of the Institute of Social and Preventive Medicine at the University of Bern and Founding Director of CTU Bern, the University’s clinical trials unit.</p>
<p>Peter is internationally renowned for his methodological work and for his clinical research on the management of cardiovascular and musculoskeletal disorders. A Fellow of the European Society of Cardiology, he has had leading roles in several major cardiovascular trials, including SIRTAX, LEADERS, FAME 2 and MATRIX, served as a member of several task forces of the European Society of Cardiology and co-authored the European guidelines on myocardial revascularization and on the management of acute myocardial infarction. Peter contributed to over 400 papers, which were cited more than 80,000 times. Since 2015 he was been recognized as <a href="https://recognition.webofsciencegroup.com/awards/highly-cited/2019/">Highly Cited Researcher</a>.</p>
<p>PUBLICATIONS:</p>
<ol>
<li>Iglesias JF, Muller O, Heg D, Roffi M, Kurz DJ, Moarof I, Weilenmann D, Kaiser C, Tapponnier M, Stortecky S, Losdat S, Eeckhout E, Valgimigli M, Odutayo A, Zwahlen M, Jüni P, Windecker S, Pilgrim T. Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients with ST-segment elevation myocardial infarction (BIOSTEMI): a single-blind, prospective, randomised superiority trial. Lancet. 2019 Oct 5;394(10205):1243-1253. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31488372">31488372</a>.</li>
<li>Fervenza FC, Appel GB, Barbour SJ, Rovin BH, Lafayette RA, Aslam N, Jefferson JA, Gipson PE, Rizk DV, Sedor JR, Simon JF, McCarthy ET, Brenchley P, Sethi S, Avila-Casado C, Beanlands H, Lieske JC, Philibert D, Li T, Thomas LF, Green DF, Juncos LA, Beara-Lasic L, Blumenthal SS, Sussman AN, Erickson SB, Hladunewich M, Canetta PA, Hebert LA, Leung N, Radhakrishnan J, Reich HN, Parikh SV, Gipson DS, Lee DK, da Costa BR, Jüni P,* Cattran DC.* Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy. N Engl J Med. 2019 Jul 4;381(1):36-46. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31269364">31269364</a>.</li>
<li>Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med. 2018 Sep 27;379(13):1224-1233. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30146969">30146969</a>.</li>
<li>Vranckx P,* Valgimigli M,* Jüni P,* Hamm C, Steg PG, Heg D, van Es GA, McFadden EP, Onuma Y, van Meijeren C, Chichareon P, Benit E, Möllmann H, Janssens L, Ferrario M, Moschovitis A, Zurakowski A, Dominici M, Van Geuns RJ, Huber K, Slagboom T, Serruys PW, Windecker S. Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial. Lancet. 2018 Sep 15;392(10151):940-949. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30166073">30166073</a>.</li>
<li>Valgimigli M, Frigoli E, Leonardi S, Vranckx P, Rothenbühler M, Tebaldi M, Varbella F, Calabrò P, Garducci S, Rubartelli P, Briguori C, Andó G, Ferrario M, Limbruno U, Garbo R, Sganzerla P, Russo F, Nazzaro M, Lupi A, Cortese B, Ausiello A, Ierna S, Esposito G, Ferrante G, Santarelli A, Sardella G, de Cesare N, Tosi P, van &#8216;t Hof A, Omerovic E, Brugaletta S, Windecker S, Heg D, Jüni P. Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial. Lancet. 2018 Sep 8;392(10150):835-848. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30153988">30153988</a>.</li>
<li>Xaplanteris P, Fournier S, Pijls NHJ, Fearon WF, Barbato E, Tonino PAL, Engstrøm T, Kääb S, Dambrink JH, Rioufol G, Toth GG, Piroth Z, Witt N, Fröbert O, Kala P, Linke A, Jagic N, Mates M, Mavromatis K, Samady H, Irimpen A, Oldroyd K, Campo G, Rothenbühler M, Jüni P,* De Bruyne B.* Five-Year Outcomes with PCI Guided by Fractional Flow Reserve. N Engl J Med. 2018 Jul 19;379(3):250-259. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/29785878">29785878</a>.</li>
<li>da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, Jüni P, Trelle S. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Lancet. 2017 Jul 8;390(10090):e21-e33. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/28699595">28699595</a>.</li>
<li>Valgimigli M, Gagnor A, Calabró P, Frigoli E, Leonardi S, Zaro T, Rubartelli P, Briguori C, Andò G, Repetto A, Limbruno U, Cortese B, Sganzerla P, Lupi A, Galli M, Colangelo S, Ierna S, Ausiello A, Presbitero P, Sardella G, Varbella F, Esposito G, Santarelli A, Tresoldi S, Nazzaro M, Zingarelli A, de Cesare N, Rigattieri S, Tosi P, Palmieri C, Brugaletta S, Rao SV, Heg D, Rothenbühler M, Vranckx P, <u>Jüni P</u>. Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial. <strong>Lancet</strong>. 2015 Jun 20. 385(9986): 2465-76. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25791214">25791214</a>.</li>
<li>Biller-Andorno N, <u>Jüni P</u>. Abolishing mammography screening programs? A view from the Swiss Medical Board. <strong>N Engl J Med</strong>. 2014 May 22. 370(21): 1965-7. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/24738641">24738641</a>.</li>
<li>De Bruyne B, Fearon WF, Pijls NH, Barbato E, Tonino P, Piroth Z, Jagic N, Mobius-Winckler S, Rioufol G, Witt N, Kala P, MacCarthy P, Engström T, Oldroyd K, Mavromatis K, Manoharan G, Verlee P, Frobert O, Curzen N, Johnson JB, Limacher A, Nüesch E, <u>Jüni P</u>. Fractional flow reserve-guided PCI for stable coronary artery disease. <strong>N Engl J Med</strong>. 2014 Sep 25. 371(13):1208-17. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25176289">25176289</a>.</li>
<li>Stefanini GG, Kalesan B, Serruys PW, Heg D, Buszman P, Linke A, Ischinger T, Klauss V, Eberli F, Wijns W, Morice MC, Di Mario C, Corti R, Antoni D, Sohn HY, Eerdmans P, van Es GA, Meier B, Windecker S, <u>Jüni P</u>. Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. <strong>Lancet</strong>. 2011 Dec 3. 378(9807):1940-8. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/22075451">22075451</a>.</li>
<li>Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, Egger M, <u>Jüni P</u>. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. <strong>BMJ</strong>. 2011 Jan 11. 342: 342:c7086. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/21224324">21224324</a>.</li>
<li>Nüesch E, Trelle S, Reichenbach S, Rutjes AW, Tschannen B, Altman DG, Egger M, <u>Jüni P</u>. Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study. <strong>BMJ</strong>. 2010 Jul 16. 341:c3515. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20639294">20639294</a>.</li>
<li>Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schömig A, Pfisterer ME, Stone GW, Leon MB, Suarez de Lezo J, Goy JJ, Park SJ, Sabaté M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, <u>Jüni P</u>. Outcomes associated with drug-eluting and bare-metal stents: A collaborative network meta-analysis. <strong>Lancet</strong>. 2007 Sep 15. 370(9591):937–48. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17869634">17869634</a>.</li>
<li>Reichenbach S, Sterchi R, Scherer M, Trelle S, Bürgi E, Bürgi U, Dieppe P, <u>Jüni P</u>. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. <strong>Ann Intern Med</strong>. 2007 Apr 17. 146(8):580-90. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17438317">17438317</a>.</li>
<li><u>Jüni P</u>, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. <strong>Lancet</strong>. 2004 Dec 4-10. 364(9450):2021-9. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/15582059">15582059</a>.</li>
<li><u>Jüni P</u>, Altman DG, Egger M. Assessing the quality of controlled clinical trials. <strong>BMJ</strong>. 2001 Jul 7. 323(7303):42-6. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/11440947">11440947</a>.</li>
<li><u>Jüni P</u>, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. <strong>JAMA</strong>. 1999 Sep 15. 282(11):1054-60. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/10493204">10493204</a>.</li>
</ol>
<p>&nbsp;</p>
<p><strong>AFFILIATIONS &amp; OTHER ACTIVITIES</strong></p>
<ul>
<li>Director, Applied Health Research Centre</li>
<li>Professor, Department of Medicine, University of Toronto</li>
<li>Professor, Institute of Health Policy, Management and Evaluation, University of Toronto</li>
</ul>
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											<h2>Bruno da Costa</h2>
					<h3>Associate Director, Applied Health Research Centre </h3>
					<h5></h5>
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						<p>Dr. Bruno R. da Costa is the Associate Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute at St. Michael&#8217;s Hospital, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation of the University of Toronto. Dr. da Costa has a PhD in Clinical Epidemiology and Biostatistics from the University of Bern (Switzerland) and Master of Science degrees in Medical Statistics from the University of Leicester (UK) and in Physical Therapy from the University of Alberta (Canada). Before joining the AHRC, Dr. da Costa was the Head of Statistics and Methodology of the Department of Cardiology as well as the Head of Clinical Research of the Institute of Primary Health Care, both at the University of Bern. Previous appointments include Assistant Professor at the Department of Physical Therapy, and Adjunct Professor at the Department of Health Policy &amp; Management, both at Florida International University.</p>
<p>&nbsp;</p>
<p>Dr. da Costa has published over seventy peer-reviewed articles and is known for his clinical research on musculoskeletal and cardiovascular conditions and for his methodological research on comparative effectiveness</p>
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											<h2>Gurpreet Lakhanpal</h2>
					<h3>Manager, Clinical Trials Unit</h3>
					<h5></h5>
					<div class="bio">
						<p>Gurpreet Lakhanpal, MSc, CCRP, PMP is the Manager of Clinical Trials Unit overseeing a team supporting all RCTs coordinated at the AHRC. She joined the AHRC in 2018 as a Project Manager overseeing the day-to-day operations of the T1ME Trial and its sub-studies, an innovative and pragmatic program bringing virtual healthcare and support mechanisms to people living with type 1 diabetes.</p>
<p>Prior to joining the AHRC, Gurpreet worked in several leading Toronto academic hospitals, including SickKids, Mount Sinai Hospital and Sunnybrook Health Sciences Centre and the CRO start-up, Ozmosis Research Inc. Gurpreet brings a wealth of knowledge in clinical research, molecular biology, project management and research operations and administration.</p>
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											<h2>Ori Rotstein</h2>
					<h3>Vice President of Research and Innovation</h3>
					<h5><p>Dr. Ori Rotstein is the Vice President of Research and Innovation at Unity Health Toronto. He is also a Professor and Associate Chair of the Department of Surgery at the University of Toronto.</p>
<p>In addition to his role as VP, Dr. Rotstein is a practicing General Surgeon, and is an acknowledged expert in the management of intra-abdominal infection and inflammation. He is the former Director of the Institute of Medical Science, University of Toronto, the postgraduate arm of the Faculty of Medicine at the University of Toronto from 2001-2011 that was responsible for graduate training programs for more than 500 MSc/PhD students. In 2012, the Institute of Medical Science honoured him with an annual lecture ‘The Ori D. Rotstein Lectureship in Translational Research’. He is a member of several prestigious medical societies including the Canadian Academy of Health Sciences, the American Surgical Association, and the American Society for Clinical Investigation. He is a Past President of the Surgical Infection Society and has contributed significantly to the activities of the American College of Surgeons through his participation on the Program Committee, Surgical Forum Committee, and the Scholarship Executive Committee.</p>
<p><strong>Research Interests</strong></p>
<p>Dr. Rotstein has a major interest in understanding how traumatic injury leads to alterations in the immune response of patients. He uses his clinical insights into the mechanisms of disease to generate novel therapeutic approaches to preventing poor outcome in these patients. His work spans the “bench to bedside” continuum, wherein he investigates cellular and animal models with a view to translating these to novel therapies in humans. This translational research has led to the investigation of the use of additives in resuscitation fluids in patients sustaining such injuries.</p>
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											<h2>Jessica Marchese</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
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						<p>Jessica Marchese, BSc, joined the AHRC&#8217;s CTU team as a Clinical Study Assistant II in July 2017. Jessica received her BSc from the University of Toronto, focusing on human biology and physiology. She also completed a post-graduate Clinical Research Certificate Program from the Michener Institute. She has previous experience in coordinating surgical oncology clinical trails, as well as qualitative studies. At AHRC, Jessica utilizes her previous experience in order to support project managers with the day-to-day management of clinical trials and general study administrative support.</p>
<p>&nbsp;</p>
<p><span style="font-family: 'Calibri Light','sans-serif'; font-size: 10.5pt;"><span style="color: #000000;"> </span></span></p>
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											<h2>Farzaana Ali</h2>
					<h3>Clinical Research Specialist </h3>
					<h5><p>Farzaana Ali, HBSc, CCRA, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and management of multi-centre randomized clinical trials. Farzaana completed her HBSc in Biology, Psychology and English from the University of Toronto and obtained her Post-Graduate Certificate in Clinical Research from Humber College. She has five years of previous experience working in various research environments, including: academic, clinical research IT, hospital (pediatric oncology) and a Phase I contract research organization.</p>
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											<h2>Sydney Currier</h2>
					<h3>Clinical Research Spcialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Sydney Currier is a clinical study assistant with the AHRC. Her previous roles have been focused on preclinical research in the field of HIV treatment, coordination of a funding program at the University of Toronto and clinical research as a member of St. Michael’s Hospital. In her current role as clinical study assistant, Sydney provides support to study project leads, assisting in the coordination of international clinical trials. She holds an Honors Bachelor of Science from the University of Toronto with a focus in Pharmaceutical Chemistry, and is currently working towards a MSc in Pharmaceutical Sciences with the Leslie Dan Faculty of Pharmacy.</p>
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											<h2>Karima Noordin</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Karima Noordin, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides administrative support in the planning and management of multi-centre randomized clinical trials. Karima has experience working in both academic and non-academic settings, and has been involved in all types of trials, including bioequivalence, phase I-IV and observational research. Karima is an active member of the Society of Clinical Research Associates (SOCRA).</p>
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											<h2>Val Panzov</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Val Panzov, MD, has more than 15 years of extensive clinical research experience as well as comprehensive clinical background. Prior to joining the Clinical Trials Unit in 2008, Dr. Panzov worked in various positions managing clinical operations, R&amp;D and business development in pharmaceutical and academic settings. As a Clinical Research Specialist, Val oversees multi-centre clinical trials and is responsible for clinical trials development in a broad range of therapeutic areas.</p>
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											<h2>Nicole Cooke</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Nicole Cooke (CCRP) is a Clinical Research Specialist within the Clinical Trials Unit. In this role, Nicole is responsible for various aspects of clinical trial management including study startup initiatives, assisting in protocol development and implementation, recruitment tracking and site-level support. With experience managing multi-center oncology trials, Nicole is familiar with central trial coordination within both academic and non-academic settings<strong><em>.</em></strong></p>
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											<h2>Danusha Nandamalavan</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p><span style="font-family: Calibri; font-size: medium;">Danusha Nandamalavan, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides support in the planning and management of multi-centre randomized clinical trials. Danusha has experience working in both academic and non-academic settings, and has been involved in all types of trials. Danusha is an active member of the Society of Clinical Research Associates (SOCRA).</span></p>
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											<h2>Samantha Saes</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Samantha Saes, HBSc, is a Clinical Research Specialist II with the Clinical Trials Unit and is responsible for the day-to-day management of multi-centre randomized clinical trials. Her responsibilities include protocol and eCRF development, site selection and management, regulatory and ethics submissions, overseeing data collection and safety reporting, and drug supply management. Prior to joining the AHRC, Samantha worked in the pharmaceutical industry for 10 years, where she gained experience in both the operational and monitoring aspects of clinical trials (phases II-IV). She has also participated in numerous audits and inspections, and has also lead many process improvement projects. Samantha completed her BSc (Hons.) in Biological Science and Nutritional Sciences at the University of Guelph and holds a certificate from the CRA &amp; CRC Program from Barnett Educational Services.</p>
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											<h2>Stephanie de Sequeira</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Stephanie de Sequeira, HBSc, MPH, is a Clinical Research Specialist with the Clinical Trials Unit, and has experience in qualitative and clinical research methodologies. Stephanie is responsible for the day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and management of multi-centre randomized clinical trials. In addition, Stephanie also helps investigators with protocol development, creation of data collection tools, and manuscript preparation. Stephanie completed her HBSc in Psychology at the University of Toronto Scarborough and her Masters of Public Health at the Dalla Lana School of Public Health at the University of Toronto.</p>
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											<h2>Gurpreet Lakhanpal</h2>
					<h3>Manager, Clinical Trials Unit</h3>
					<h5></h5>
					<div class="bio">
						<p>Gurpreet Lakhanpal, MSc, CCRP, PMP is the Manager of Clinical Trials Unit overseeing a team supporting all RCTs coordinated at the AHRC. She joined the AHRC in 2018 as a Project Manager overseeing the day-to-day operations of the T1ME Trial and its sub-studies, an innovative and pragmatic program bringing virtual healthcare and support mechanisms to people living with type 1 diabetes.</p>
<p>Prior to joining the AHRC, Gurpreet worked in several leading Toronto academic hospitals, including SickKids, Mount Sinai Hospital and Sunnybrook Health Sciences Centre and the CRO start-up, Ozmosis Research Inc. Gurpreet brings a wealth of knowledge in clinical research, molecular biology, project management and research operations and administration.</p>
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											<h2>Rekha Thomas</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Rekha Thomas is a Clinical Research Specialist II with the Clinical Trials Unit at AHRC, responsible for the day to day management of the clinical trial.  In her role, she provides support in the planning and management of multi-center randomized clinical trials in various aspects including regulatory submissions, study startup initiatives, site communications, study operations, supply management.</p>
<p>Rekha has vast experience working on Phase I-II trials, Public health projects on alcohol and drug addictions and Community engagement trials on opioid overdose. Rekha also carries experience in setting up the infrastructure and processes of a Research Ethics Office in academic setting.</p>
<p>Rekha completed her Honors in Cell &amp; Molecular Biology from the University of Toronto followed by Post-Graduation in Clinical Research from Humber College. Rekha is an active member of the SOCRA since 2009.</p>
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											<h2>Kevin Thorpe</h2>
					<h3>Head of Biostatistics</h3>
					<h5></h5>
					<div class="bio">
						<p>Kevin Thorpe, MMath, has over 20 years of experience in clinical research as a biostatistician and methodologist. He is currently an Assistant Professor in the Dalla Lana School of Public Health at the University of Toronto and is Head of Biostatistics and a methodologist with the AHRC, where he specializes in clinical trials.</p>
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											<h2>Sorcha Mulligan</h2>
					<h3>Clinical Research Specialist</h3>
					<h5><p>Sorcha is a Clinical Research Specialist with the Clinical Trials Unit. She is responsible for the daily project management of a number of international multi-centre trials, including preparing documentation and regulatory submissions, site set-up and training, recruitment monitoring and supply management.</p>
<p>Before joining the AHRC, Sorcha spent over six years at the University of Oxford’s Clinical Trials Service Unit (CTSU) at the Nuffield Department of Population Health (NDPH). She worked as a Clinical Trial Manager on large-scale international renal and cardiovascular trials. Prior to this, Sorcha worked in the NDPH Wolfson Laboratories as a Scientific Officer and Laboratory Training Officer, on large observational studies and randomised trials. She completed a bachelors’ degree in Physiology at Trinity College, Dublin.</p>
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											<h2>Melissa Giamou</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Melissa Giamou has a BSc (Hons.) in Biology from the University of Western Ontario, and joined AHRC in 2013 through an internship for a Postgraduate Diploma in Clinical Trials Management. Melissa oversees multi-centre randomized clinical trials, particularly in the therapeutic areas of cardiology and medical devices. In her role as a Clinical Research Specialist, Melissa coordinates electronic case report form development, oversees data collection and safety reporting, creates and maintains essential project documents, helps manage study budgets, payments and contracts, along with conducting other operational activities.</p>
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					<div style="display:none" id="health-economics-deena">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2017/11/IMG_1207-2-220x220.jpg" alt="" />
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											<h2>Deena</h2>
					<h3>Research Assistant</h3>
					<h5></h5>
					<div class="bio">
						<p>Deena, M.B.B.S., is a Research Assistant at the CLEAR. Her role encompasses taking care of the administrative processes of the organization and assisting the Principal Investigator with ongoing research activities including the submissions of REB applications, grants, and manuscripts, conducting literature reviews, and performing data analyses. She recently completed the Internationally Trained Medical Doctors (ITMD) Bridging Program at Ryerson University, where she gained exposure in Health Informatics, Communication and Leadership skills, Research Methodologies, and Project Management. As an internationally trained medical graduate, she has a strong clinical background from her experience working in the Family Medicine and Community Health fields.</p>
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											<h2>Desmond Loong</h2>
					<h3>Health Economist</h3>
					<h5></h5>
					<div class="bio">
						<p>Desmond Loong holds an MSc in Health Services Research from the University of Toronto’s Institute of Health Policy, Management and Evaluation (IHPME).  Specializing in health outcomes and evaluation, Desmond has experience conducting economic evaluations using person-level data – as well as experience in mental health services research, program evaluations, systematic literature reviews, database management, and data analysis using STATA and SPSS. Desmond’s current focus is working with decision-makers and clinical researchers to evaluate and show the value of interventions.</p>
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											<h2>Ashna Jinah</h2>
					<h3>Health Economist</h3>
					<h5><p>Ashna Jinah received her MSc in Epidemiology &amp; Biostatistics from the Schulich School of Medicine &amp; Dentistry at Western University. She has obtained work experience in public health and clinical research settings. Her research interests include the epidemiology of chronic and infectious disease, health economics, global public health, health services outcomes and evaluation, and knowledge translation. At CLEAR, Ashna will be applying her knowledge and expertise gained from her multidisciplinary background and collaborating with stakeholders in health care to improve the efficiency of our system.</p>
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											<h2>Hailey Saunders</h2>
					<h3>Health Economist</h3>
					<h5><p>Hailey Saunders received her MSc in Epidemiology &amp; Biostatistics from Western University. She has experience conducting economic analyses to show the value of health interventions or to examine their potential economic impact for interventions such as mental health and addictions programs, and cancer treatments. In her current role, she uses various methodologies and software to help create economic evidence to support decision-makers, health professionals, and researchers</p>
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											<h2>Lisa Masucci</h2>
					<h3>Health Economist</h3>
					<h5></h5>
					<div class="bio">
						<p>Lisa Masucci received her MSc in Health Services Research from the Institute of Health Policy, Management and Evaluation at the University of Toronto, specializing in health outcomes and evaluation. She has experience in conducting cost-effectiveness and budget impact analyses for both research and decision-making settings. She previously conducted economic analyses for the Ontario Health Technology Advisory Committee (OHTAC) and Vancouver Coastal Health. Her research interests include health technology assessment, health services outcomes and evaluation, health care priority setting and knowledge translation.</p>
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											<h2>Kari Ala-Leppilampi</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Kari Ala-leppilampi received a Master of Planning (MPl) degree from Ryerson University’s School of Regional and Urban Planning and an MSc in Health Promotion from the Dalla Lana School of Public Health, University of Toronto. Through his graduate level training and employment in both urban planning and public health research, Kari brings a broad base of knowledge to his role at AHRC, and a uniquely valuable multidisciplinary perspective. While his specialty is qualitative inquiry, Kari is also well versed in quantitative and mixed methods approaches, and has taught courses on research theory and methods. His research has focused on a wide range of issues including outcomes associated with illicit drug policy, criminal justice diversion programs, mental health and addiction treatment services, and policies in relation to the provision of affordable and supportive housing. In keeping with his personal interest in physical activity, his research has also focused on the social benefits of active transportation, and the potential role of exercise and sport in recovery from mental health and addiction issues. As a Clinical Research Specialist, Kari focuses on qualitative, health services research by coordinating research studies, and conducting qualitative interviews and analysis on a range of health related interventions.</p>
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											<h2>Gerald Lebovic</h2>
					<h3>Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Gerald Lebovic received an MSc in Statistics and a PhD in Biostatistics from the University of Toronto. He has 10 years of experience working on observational studies and has consulted on a variety of studies in the medical field. Currently, Gerald is a biostatistician at the HUB and an Assistant Professor at the Institute of Health Policy, Management and Evaluation at the University of Toronto. Gerald works with numerous researchers from various disciplines on a variety of observational studies. His research interests include health services research, longitudinal data analysis, observational studies and multi-state models.</p>
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											<h2>Ben Markowitz</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Ben Markowitz completed his BSc (Hons) in Kinesiology from the University of Western Ontario, and received an MSc from the Institute of Medical Science at the University of Toronto. Ben joins the AHRC with experience conducting qualitative health research at St. Michael’s Hospital and Women’s College Hospital. As a Master’s student, Ben used a narrative methodology to assess transitions from pediatric into adult diabetes care. For his prior research, Ben was honoured with a Queen Elizabeth II Graduate Scholarship in Science and Technology. Ben has also published research in the Canadian Journal of Diabetes and presented original findings at the American Diabetes Association’s Scientific Sessions. As a Clinical Research Specialist at the AHRC, Ben continues to pursue his interest in using qualitative inquiry to positively impact health services.</p>
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											<h2>Tiffany Jefkins</h2>
					<h3>Clinical Research Specialist </h3>
					<h5><p>Tiffany Jefkins, PhD(c), is a Clinical Research Specialist with OEQRU at AHRC. Tiffany specializes in data management, project planning and coordination of studies in the prehospital setting. She is currently working with C-SCAN (Canadian Sudden Cardiac Arrest Network) registry, a collaboration between the Cardiac Arrhythmia Network of Canada (CANet) and the Canadian Resuscitation Outcomes Consortium (CanROC). Prior to joining the AHRC, Tiffany worked for six years as a Respiratory Therapist in Critical Care. She is currently a doctoral student at the University of Toronto – Institute of Health Policy, Management and evaluation – Health services Research where she is focusing on lay responder experiences during an out-of-hospital cardiac arrest.</p>
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											<h2>Cheryl Pritlove</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Cheryl Pritlove, PhD, is a Clinical Research Specialist, employing qualitative methods to the study of a variety of health-related research topics, including cardiac health and diabetes. She has extensive experience and expertise in qualitative and arts-based methods, health policy, and psychosocial oncology. Cheryl has a BA in Health and Society and an MSc in Kinesiology and Health Science from York University. She conducted her doctoral research at the Princess Margaret Cancer Centre where she worked with patients as well as health care and service providers to identify gaps in the delivery of cancer care and explored innovative approaches to (acute/chronic) care integration.  She has conducted health services research with a number of organizations including Wellspring, ELLICSR Health, Wellness and Cancer Survivorship Centre, as well as the University of Toronto and York University.</p>
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											<h2>Rosane Nisenbaum</h2>
					<h3>Associate Scientist and Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Rosane Nisenbaum, PhD, has special interest in multi-level models, longitudinal and categorical data analysis and multiple imputation applied to neighborhood effects on mental health, and homelessness and housing studies. She provides assistance in the design and analysis of studies conducted by St. Michael’s investigators, fellows and students and is a member of St. Michael’s Research Ethics Board. Dr. Nisenbaum is an Assistant Professor in the Division of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, co-teaching the course ‘Laboratory in Statistical Design &amp; Analysis’ and serving as a Practicum supervisor.</p>
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											<h2>Roula Raptis</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Roula (Stavroula) Raptis, MSc, has a diverse research background and interests, lending well to her analytical skills and ability to work with multi-disciplinary teams. Roula completed her BSc at the University of Waterloo, with a focus in cell and molecular biology and microbiology. She went on to complete an MSc degree at the University of Toronto in the Department of Laboratory Medicine and Pathobiology. There she explored gene polymorphisms in cancer susceptibility genes and was a member of a large, nationally funded initiative &#8211; the interprovincial Colorectal Cancer Interdisciplinary Health Research Team. Roula has experience in both academic and nonacademic settings, including working for an independent analytical laboratory for several years, as well as in various teaching environments. In her current role with the Observational Epidemiology and Qualitative Research Unit, Roula is involved in study design, patient registry and database design, protocol and data collection form development, study planning and operations, and research communications. She is the author of a book chapter on genetic instability, and an author and co-author on several additional peer-reviewed publications.</p>
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											<h2>Agota Ferenc</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Agota Ferenc, MSc, ACRP-CP is a Clinical Research Specialist with the Observational Epidemiology &amp; Qualitative Research team and is responsible for the day-to-day project management of various clinical studies. Agota oversees clinical operations activities from study start-up to close-out including but not limited to: protocol development; research ethics submission; electronic case report form creation; essential document creation; trial master file (TMF) maintenance; and the management of study budgets, payments and contracts. Prior to joining AHRC, she worked in the CRO industry. She holds a Master of Science in Human Health from the University of Guelph and a Clinical Research Graduate Certificate from Seneca College. Agota is an active member of the Association of Clinical Research Professionals (ACRP).</p>
					</div>
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											<h2>Janet Parsons</h2>
					<h3>Scientist</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Janet Parsons, PhD, is a Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital with expertise in qualitative research methods. Dr. Parsons specializes in visual and narrative methods, and is engaged in a program of film-based research. Additional research interests include health equity, oncology, knowledge translation, and health services research. A physiotherapist, Dr. Parsons practiced for 18 years in acute-care teaching hospitals and is cross-appointed to the Department of Physical Therapy, University of Toronto.</p>
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											<h2>Courtney Truong</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Courtney Truong, HBSc, AEMCA is a Clinical Research Specialist with OEQRU. Courtney specializes in data management, coordination of registries, and observational studies/clinical trials in the prehospital setting. She is currently working on the R3 (local) and CanROC (national) projects which are registries looking at out-of-hospital cardiac arrests and traumatic cardiac arrests.</p>
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											<h2>Mercy Charles</h2>
					<h3>Research Coordinator </h3>
					<h5><p>Mercy Charles is a certified Clinical Research Professional (CCRP) with 12 years of clinical research experience in various roles working in a wide range of Phase I-Phase II studies for Clinical Research Organizations (CRO). Mercy completed her Bachelors of Science (BSc.) in Applied Chemistry and Biology from Ryerson University and has obtained a Clinical Research Graduate Certificate from the Michener Institute. She is an active member of the Society of Clinical Research Associate (SOCRA) and has maintained her certification as a Clinical Research Professional since 2008. Currently, Mercy is working at the Applied Health Research Centre (AHRC) as a Research Coordinator III. She is responsible for day-to-day management of The Surviving Opioid Overdose with Naloxone Education and Resuscitation (SOONER) Project.</p>
</h5>
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											<h2>Clara Juando-Prats</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Clara Juando-Prats, PhD, MSc, BScN, is a Clinical Research Specialist at the AHRC. She completed her PhD at Faculty of Nursing in the University of Toronto, her MSc at the University of Edinburgh (UK), and the BScN at the Autonomous University of Barcelona (Spain). Clara uses visual methods and critical social theory to study access and utilization to the health care resources by vulnerable populations in Toronto. Her work with young mothers with low resources, young parents living in the margins, and in partnership with community agencies, aims to positively impact the physical and mental health of this population while giving them social connections with health care providers. Prior to joining the HUB, Clara was the leader of the Knowledge Translation and Nursing Research Unit at the Hospital Sant Pau in Barcelona, developing and evaluating projects studies related to clinical safety, knowledge translation, and nursing leadership. At the Hospital Sant Pau, Clara also worked as a nurse, a research nurse, and as an specialist in qualitative methods at the Epidemiology Department. She has been collaborating for several years with the Cochrane Collaboration and the Joanna Briggs Institute as an instructor and reviewer. During 2013 and 2012 she completed two fellowships, at the Spanish Ministry of Health in qualitative research with marginalized women, and at the Centre for Global Health at the University of Ottawa in Complex Interventions and Knowledge Mobilization. The focus of Clara’s work at the AHRC has been evaluation of complex interventions, qualitative and mixed methods designs for health research, knowledge translation and health inequities.</p>
<p>&nbsp;</p>
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											<h2>Audra Stitt</h2>
					<h3>Manager of the Observational Epidemiology and Qualitative Research Unit</h3>
					<h5></h5>
					<div class="bio">
						<p>Audra Stitt, MSc is the Manager of the Observational Epidemiology and Qualitative Research Unit of the AHRC. Audra brings more than 17 years of experience with public health research, population and cohort based observation studies and clinical trials and has been managing research teams since 2010. She has extensive experience with data abstraction (in both prehospital and hospital settings), large administrative data sets, project management, and education. Audra is responsible for the oversight of observational and qualitative research studies as well as the planning and operations of patient registries.</p>
<p>&nbsp;</p>
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											<h2>Sahar Ehtesham</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Sahar is working as a Clinical Research Specialist in Observational Epidemiology and Qualitative Research Unit. She is responsible for managing multi-site studies from the coordinating centre.</p>
<p>&nbsp;</p>
<p>Sahar has over 14 years of experience working in Clinical Research on investigator initiated as well as industry sponsored studies.  She has been involved in conducting day to day tasks for observational studies.  Additionally, Sahar has managed multi-site national observational studies and multi-site international clinical trials.  Through the various roles Sahar has held, she has had the opportunity to contribute to every aspect and stage of clinical research including, assisting in drafting study protocols, grant applications and manuscripts, completing regulatory and ethical applications, formulating budgets, initiating study sites, data management and analysis.</p>
<p>&nbsp;</p>
<p>Sahar has received HBSc in Cell and Molecular Biology from University of Toronto and MSc in Health Research Methodology from McMaster University.  she has also completed a Clinical Research Associate program at Michener Institute.  Sahar authored several manuscripts that have been published in peer reviewed journals. she has also authored and presented posters at conferences.</p>
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											<h2>Shawn Nnorom</h2>
					<h3>Clinical Study Assistant</h3>
					<h5></h5>
					<div class="bio">
						<p>Shawn Nnorom, is a Clinical Study Assistant II with the Observational Epidemiology and Qualitative Research Unit at AHRC. He is responsible for providing support and assistance to the CSAs in their management of the multi-centered trials. Prior to working at AHRC, Shawn had worked for a number of years in the pharmaceutical/healthcare industry at various public and private institutions. Shawn holds a BSc. In Biochemistry from the University of Ottawa and a Postgraduate Certificate in Clinical Research from Humber College.</p>
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											<h2>Emma Richardson</h2>
					<h3>Clinical Research Specialist </h3>
					<h5><p>Dr. Emma Richardson is Applied Health Research Specialist and Assistant Professor at the Department of Health Research, Methods, Evidence and Impact at McMaster University.  Her maternal health research builds on her field experience working with the United Nations in Nicaragua, Honduras and Guatemala and internationally as a strategic planning consultant with the United Nations System Staff College.  Emma worked previously at St. Michael’s Hospital with the Centre for Ethical, Social and Cultural Risk and at the Evaluation Centre for Complex Health Interventions. She holds a Phd in Health and Behavioural Sciences from the University of Toronto, an MSc in Development Studies from the London School of Economics and a BA in Economics and International Studies, with a focus on Latin America, from the University of North Carolina at Chapel Hill.  Emma has an interest in applying realist evaluation and community engagement approaches to critical qualitative health research and strives to conduct research at the intersection with programming and policy.</p>
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											<h2>Christopher Allen</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Christopher Allen, BSc, has both clinical and basic research experience. He has a BSc (Hons.) in Biochemistry and Molecular Biology and his graduate work is in cancer immunology. He has more than three years of clinical research experience in hematology/oncology. As a Clinical Research Specialist in the Observational Epidemiology and Qualitative Research Unit, Christopher oversees several projects. His roles involve study design and initiation, site management, development of case report forms and databases, data collection and quality control, research communications, and site reimbursement.</p>
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											<h2>Bruno da Costa</h2>
					<h3>Associate Director, Applied Health Research Centre </h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Bruno R. da Costa is the Associate Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute at St. Michael&#8217;s Hospital, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation of the University of Toronto. Dr. da Costa has a PhD in Clinical Epidemiology and Biostatistics from the University of Bern (Switzerland) and Master of Science degrees in Medical Statistics from the University of Leicester (UK) and in Physical Therapy from the University of Alberta (Canada). Before joining the AHRC, Dr. da Costa was the Head of Statistics and Methodology of the Department of Cardiology as well as the Head of Clinical Research of the Institute of Primary Health Care, both at the University of Bern. Previous appointments include Assistant Professor at the Department of Physical Therapy, and Adjunct Professor at the Department of Health Policy &amp; Management, both at Florida International University.</p>
<p>&nbsp;</p>
<p>Dr. da Costa has published over seventy peer-reviewed articles and is known for his clinical research on musculoskeletal and cardiovascular conditions and for his methodological research on comparative effectiveness</p>
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											<h2>Peter Jüni</h2>
					<h3>Director, Applied Health Research Centre</h3>
					<h5></h5>
					<div class="bio">
						<p>Peter is the Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, holds a Tier 1 Canada Research Chair in Clinical Epidemiology of Chronic Diseases, and is a Professor at the Department of Medicine and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He is a graduate of the Faculty of Medicine at the University of Bern in Switzerland, completed his training in internal medicine at various hospitals in Switzerland, and was a Research Fellow at the Department of Social Medicine at the University of Bristol, UK. Prior to joining St. Michael’s Hospital, Peter was the Director of the Institute of Primary Health Care and Professor of Primary Care and Clinical Epidemiology at the Faculty of Medicine at the University of Bern in Switzerland. He held previous appointments as Director of the Institute of Social and Preventive Medicine at the University of Bern and Founding Director of CTU Bern, the University’s clinical trials unit.</p>
<p>Peter is internationally renowned for his methodological work and for his clinical research on the management of cardiovascular and musculoskeletal disorders. A Fellow of the European Society of Cardiology, he has had leading roles in several major cardiovascular trials, including SIRTAX, LEADERS, FAME 2 and MATRIX, served as a member of several task forces of the European Society of Cardiology and co-authored the European guidelines on myocardial revascularization and on the management of acute myocardial infarction. Peter contributed to over 400 papers, which were cited more than 80,000 times. Since 2015 he was been recognized as <a href="https://recognition.webofsciencegroup.com/awards/highly-cited/2019/">Highly Cited Researcher</a>.</p>
<p>PUBLICATIONS:</p>
<ol>
<li>Iglesias JF, Muller O, Heg D, Roffi M, Kurz DJ, Moarof I, Weilenmann D, Kaiser C, Tapponnier M, Stortecky S, Losdat S, Eeckhout E, Valgimigli M, Odutayo A, Zwahlen M, Jüni P, Windecker S, Pilgrim T. Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients with ST-segment elevation myocardial infarction (BIOSTEMI): a single-blind, prospective, randomised superiority trial. Lancet. 2019 Oct 5;394(10205):1243-1253. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31488372">31488372</a>.</li>
<li>Fervenza FC, Appel GB, Barbour SJ, Rovin BH, Lafayette RA, Aslam N, Jefferson JA, Gipson PE, Rizk DV, Sedor JR, Simon JF, McCarthy ET, Brenchley P, Sethi S, Avila-Casado C, Beanlands H, Lieske JC, Philibert D, Li T, Thomas LF, Green DF, Juncos LA, Beara-Lasic L, Blumenthal SS, Sussman AN, Erickson SB, Hladunewich M, Canetta PA, Hebert LA, Leung N, Radhakrishnan J, Reich HN, Parikh SV, Gipson DS, Lee DK, da Costa BR, Jüni P,* Cattran DC.* Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy. N Engl J Med. 2019 Jul 4;381(1):36-46. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31269364">31269364</a>.</li>
<li>Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med. 2018 Sep 27;379(13):1224-1233. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30146969">30146969</a>.</li>
<li>Vranckx P,* Valgimigli M,* Jüni P,* Hamm C, Steg PG, Heg D, van Es GA, McFadden EP, Onuma Y, van Meijeren C, Chichareon P, Benit E, Möllmann H, Janssens L, Ferrario M, Moschovitis A, Zurakowski A, Dominici M, Van Geuns RJ, Huber K, Slagboom T, Serruys PW, Windecker S. Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial. Lancet. 2018 Sep 15;392(10151):940-949. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30166073">30166073</a>.</li>
<li>Valgimigli M, Frigoli E, Leonardi S, Vranckx P, Rothenbühler M, Tebaldi M, Varbella F, Calabrò P, Garducci S, Rubartelli P, Briguori C, Andó G, Ferrario M, Limbruno U, Garbo R, Sganzerla P, Russo F, Nazzaro M, Lupi A, Cortese B, Ausiello A, Ierna S, Esposito G, Ferrante G, Santarelli A, Sardella G, de Cesare N, Tosi P, van &#8216;t Hof A, Omerovic E, Brugaletta S, Windecker S, Heg D, Jüni P. Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial. Lancet. 2018 Sep 8;392(10150):835-848. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/30153988">30153988</a>.</li>
<li>Xaplanteris P, Fournier S, Pijls NHJ, Fearon WF, Barbato E, Tonino PAL, Engstrøm T, Kääb S, Dambrink JH, Rioufol G, Toth GG, Piroth Z, Witt N, Fröbert O, Kala P, Linke A, Jagic N, Mates M, Mavromatis K, Samady H, Irimpen A, Oldroyd K, Campo G, Rothenbühler M, Jüni P,* De Bruyne B.* Five-Year Outcomes with PCI Guided by Fractional Flow Reserve. N Engl J Med. 2018 Jul 19;379(3):250-259. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/29785878">29785878</a>.</li>
<li>da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, Jüni P, Trelle S. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Lancet. 2017 Jul 8;390(10090):e21-e33. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/28699595">28699595</a>.</li>
<li>Valgimigli M, Gagnor A, Calabró P, Frigoli E, Leonardi S, Zaro T, Rubartelli P, Briguori C, Andò G, Repetto A, Limbruno U, Cortese B, Sganzerla P, Lupi A, Galli M, Colangelo S, Ierna S, Ausiello A, Presbitero P, Sardella G, Varbella F, Esposito G, Santarelli A, Tresoldi S, Nazzaro M, Zingarelli A, de Cesare N, Rigattieri S, Tosi P, Palmieri C, Brugaletta S, Rao SV, Heg D, Rothenbühler M, Vranckx P, <u>Jüni P</u>. Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial. <strong>Lancet</strong>. 2015 Jun 20. 385(9986): 2465-76. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25791214">25791214</a>.</li>
<li>Biller-Andorno N, <u>Jüni P</u>. Abolishing mammography screening programs? A view from the Swiss Medical Board. <strong>N Engl J Med</strong>. 2014 May 22. 370(21): 1965-7. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/24738641">24738641</a>.</li>
<li>De Bruyne B, Fearon WF, Pijls NH, Barbato E, Tonino P, Piroth Z, Jagic N, Mobius-Winckler S, Rioufol G, Witt N, Kala P, MacCarthy P, Engström T, Oldroyd K, Mavromatis K, Manoharan G, Verlee P, Frobert O, Curzen N, Johnson JB, Limacher A, Nüesch E, <u>Jüni P</u>. Fractional flow reserve-guided PCI for stable coronary artery disease. <strong>N Engl J Med</strong>. 2014 Sep 25. 371(13):1208-17. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25176289">25176289</a>.</li>
<li>Stefanini GG, Kalesan B, Serruys PW, Heg D, Buszman P, Linke A, Ischinger T, Klauss V, Eberli F, Wijns W, Morice MC, Di Mario C, Corti R, Antoni D, Sohn HY, Eerdmans P, van Es GA, Meier B, Windecker S, <u>Jüni P</u>. Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. <strong>Lancet</strong>. 2011 Dec 3. 378(9807):1940-8. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/22075451">22075451</a>.</li>
<li>Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, Egger M, <u>Jüni P</u>. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. <strong>BMJ</strong>. 2011 Jan 11. 342: 342:c7086. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/21224324">21224324</a>.</li>
<li>Nüesch E, Trelle S, Reichenbach S, Rutjes AW, Tschannen B, Altman DG, Egger M, <u>Jüni P</u>. Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study. <strong>BMJ</strong>. 2010 Jul 16. 341:c3515. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20639294">20639294</a>.</li>
<li>Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schömig A, Pfisterer ME, Stone GW, Leon MB, Suarez de Lezo J, Goy JJ, Park SJ, Sabaté M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, <u>Jüni P</u>. Outcomes associated with drug-eluting and bare-metal stents: A collaborative network meta-analysis. <strong>Lancet</strong>. 2007 Sep 15. 370(9591):937–48. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17869634">17869634</a>.</li>
<li>Reichenbach S, Sterchi R, Scherer M, Trelle S, Bürgi E, Bürgi U, Dieppe P, <u>Jüni P</u>. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. <strong>Ann Intern Med</strong>. 2007 Apr 17. 146(8):580-90. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17438317">17438317</a>.</li>
<li><u>Jüni P</u>, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. <strong>Lancet</strong>. 2004 Dec 4-10. 364(9450):2021-9. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/15582059">15582059</a>.</li>
<li><u>Jüni P</u>, Altman DG, Egger M. Assessing the quality of controlled clinical trials. <strong>BMJ</strong>. 2001 Jul 7. 323(7303):42-6. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/11440947">11440947</a>.</li>
<li><u>Jüni P</u>, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. <strong>JAMA</strong>. 1999 Sep 15. 282(11):1054-60. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/10493204">10493204</a>.</li>
</ol>
<p>&nbsp;</p>
<p><strong>AFFILIATIONS &amp; OTHER ACTIVITIES</strong></p>
<ul>
<li>Director, Applied Health Research Centre</li>
<li>Professor, Department of Medicine, University of Toronto</li>
<li>Professor, Institute of Health Policy, Management and Evaluation, University of Toronto</li>
</ul>
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											<h2>Kevin Thorpe</h2>
					<h3>Head of Biostatistics</h3>
					<h5></h5>
					<div class="bio">
						<p>Kevin Thorpe, MMath, has over 20 years of experience in clinical research as a biostatistician and methodologist. He is currently an Assistant Professor in the Dalla Lana School of Public Health at the University of Toronto and is Head of Biostatistics and a methodologist with the AHRC, where he specializes in clinical trials.</p>
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											<h2>Rosane Nisenbaum</h2>
					<h3>Associate Scientist and Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Rosane Nisenbaum, PhD, has special interest in multi-level models, longitudinal and categorical data analysis and multiple imputation applied to neighborhood effects on mental health, and homelessness and housing studies. She provides assistance in the design and analysis of studies conducted by St. Michael’s investigators, fellows and students and is a member of St. Michael’s Research Ethics Board. Dr. Nisenbaum is an Assistant Professor in the Division of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, co-teaching the course ‘Laboratory in Statistical Design &amp; Analysis’ and serving as a Practicum supervisor.</p>
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											<h2>Charles Keown-Stoneman</h2>
					<h3>Biostatistician</h3>
					<h5><p>Dr. Charlie Keown-Stoneman, received his PhD and MSc in Applied Statistics and BSc in Biological Science from the University of Guelph. Charlie has experience teaching undergraduate statistics courses at the University of Guelph as a sessional lecturer, and providing statistical consulting for the Mood Disorder Centre of Ottawa at the University of Ottawa Health Services. In his current role at the AHRC, Charlie provides statistical analysis and support for observational studies and randomized trials, primarily using R and SAS. His research interests include survival analysis, multi-state models, and longitudinal data analysis.</p>
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											<h2>Fei Zuo</h2>
					<h3>Research Biostatistician</h3>
					<h5></h5>
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						<p>Fei Zuo, MPH, is a Research Biostatistician at the AHRC. Fei collaborates with researchers from various disciplines and provides statistical support for randomized clinical trials. Prior to joining the AHRC in 2018, Fei worked in the pharmaceutical industry as a statistical programmer, and in the provincial government as a research epidemiologist. Fei holds a Masters of Public Health in Epidemiology from the University of Toronto.</p>
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											<h2>Gerald Lebovic</h2>
					<h3>Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Gerald Lebovic received an MSc in Statistics and a PhD in Biostatistics from the University of Toronto. He has 10 years of experience working on observational studies and has consulted on a variety of studies in the medical field. Currently, Gerald is a biostatistician at the HUB and an Assistant Professor at the Institute of Health Policy, Management and Evaluation at the University of Toronto. Gerald works with numerous researchers from various disciplines on a variety of observational studies. His research interests include health services research, longitudinal data analysis, observational studies and multi-state models.</p>
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											<h2>Malini Handa Leno</h2>
					<h3>Manager, Business Operations</h3>
					<h5></h5>
					<div class="bio">
						<p>Malini Handa Leno, MSc, MBA, PMP, is the Manager, Business Operations, and is accountable for financial, human resource, and contract management at the AHRC. Malini joined the AHRC with 15 years of experience in the pharmaceutical, CRO, and hospital sectors. Her previous roles have focused on clinical trial management, patient safety and risk management, and most recently, the implementation of information management systems to help transform health care. Malini holds an MBA from the Desautels Faculty of Management at McGill University, and an MSc in Pharmacology from Dalhousie University.</p>
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											<h2>Daniel Jin</h2>
					<h3>Business Analyst</h3>
					<h5><p>Daniel Jin is the Business Analyst at the AHRC. He supports the leadership and project teams with business strategies and planning along with financial management. Daniel has previous experience in business and project operation in both pharmaceutical and hospital sectors. He most recently worked as a project manager in the Clinical Trials Unit at the AHRC. Daniel holds a HBSc in Biology and Psychology from the University of Toronto.</p>
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											<h2>Joanne Roberti</h2>
					<h3>Administrative Assistant </h3>
					<h5><p>Joanne Roberti is the Administrative Assistant to Dr. Peter Jüni, the Director AHRC, working closely with him to provide personalized support of his (as well as departmental and hospital) goals and objectives. She is the administrative point of contact between the Director, AHRC and the AHRC staff, internal partners, and external clients.</p>
<p>Joanne has a BA from the University of Toronto, and a well-rounded portfolio of administrative skills with over 20 years of experience in research and education sectors. Prior to joining  the AHRC , she worked for 10 years at The Centre for Phenogenomics, a research facility owned and operated by Mount Sinai Hospital and The Hospital for Sick Children, where she provided a wide variety of administrative and project support, including event planning to a Senior Associate Scientist /Director of Research Partnerships, and Service Cores staff.</p>
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											<h2>Carrie Adams</h2>
					<h3>Business Coordinator</h3>
					<h5><p>Carrie Adams is the Business Coordinator for the AHRC who is responsible for overseeing the payroll and organization of daily operations for the team, as well as supporting the process of finance-related deliverables. Carrie holds a Bachelor of Health Administration (BHA) with distinction from Ryerson University, and is completing a Master of Health Administration (MHA) from the University of Regina. In addition, she comes to the AHRC team with over 20 years of hospital administration experience, a Lean Yellow Belt Certificate from the Leading Edge Group, and is a current member of the Canadian College of Health Leaders (CCHL).</p>
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											<h2>Melissa Tom</h2>
					<h3>SAS Programmer / Research Data Management Specialist</h3>
					<h5></h5>
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						<p>Melissa Tom is a SAS Programmer and Research Data Management Specialist and has been with the Research Information Systems team since December 2012. In her role at the AHRC, she is responsible for data management, data extraction and reporting of clinical data. Melissa has several years of experience using SAS.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2018/11/no-photo-available-220x220.jpg" alt="" />
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											<h2>Marla Campbell</h2>
					<h3>Research Applications Support Specialist</h3>
					<h5><p>Marla joined the Research Information Systems team as a Research Applications Support Specialist in July of 2019.  Her role at the AHRC includes server and database administration activities in addition to custom development work.  Marla has over 10 years of experience providing technical solutions and holds a B.S. in Computer and Information Science.</p>
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											<h2>Maria Naydenova</h2>
					<h3>Senior Research Database Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Maria Naydenova, MD, has more than 15 years of clinical research experience and a strong clinical background. She received an MD in Plovdiv Medical University, Bulgaria. As a Research Database Specialist at the AHRC, Maria is responsible for the design, build, and support of clinical studies in various electronic data capture systems. Prior to joining the Research Information Systems team in 2010, Maria worked in pharmaceutical industries and health care sectors monitoring sites and overseeing clinical trial data for national and international clinical trials.</p>
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											<h2>Kosma Wysocki</h2>
					<h3>Manager, Research Information Systems</h3>
					<h5></h5>
					<div class="bio">
						<p>Kosma Wysocki, B.Sc. Supports the AHRC’s applications through regular system and database administration and maintenance activities as well as performing custom development work as required. Kosma brings over five years of experience in technical support and systems administration experience to the AHRC.</p>
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											<h2>Pamela De Verno</h2>
					<h3>Senior Research Database Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Pamela De Verno, MSc, has over 15 years of clinical research experience, as well as extensive experience in biotechnology research and development. As a Research Database Specialist with the Research Information Systems team, Pamela is responsible for the design, build and support of studies within a data management system for storage, validation and retrieval of clinical data.</p>
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											<h2>Bryan Boodhoo</h2>
					<h3>Research Database Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Bryan Boodhoo, MSc, has more than 20 years of clinical trials research experience, predominantly in the pharmaceutical industry. He works with the Research Information Systems team as an expert in Clinical Data Programming with thorough technical understanding in the design, setup and validation of databases, creating edit checks, data extraction and transformation, and generating formatted reports and listings using SAS, RAVE, Oracle Clinical or INFORM.</p>
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											<h2>Althea Ambosta Logan</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p><span style="font-family: Calibri; font-size: medium;">Althea Ambosta Logan, M.A., CCRP, is a Data Management Specialist with the Research Information Systems team at the AHRC. Althea is responsible for reviewing data from multi-centre clinical trials and observational studies in Medidata RAVE and REDCap, with the goal of ensuring a high level of data quality. Althea is also involved in creating data management plans, performing validation activities on electronic case report forms and generating data management reports. Prior to her current role, Althea was a Clinical Research Specialist at the AHRC and was involved in the management and day-to-day operations of several multi-centre observational research studies. Althea holds a B.A. in Psychology from York University and an M.A. in Psychology (Brain and Cognitive Science Program) from the University of Manitoba. </span></p>
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											<h2>Danny Marchese</h2>
					<h3>Research Database Specialist </h3>
					<h5></h5>
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						<p>Danny Marchese has been working with St. Michael’s Hospital since June of 2000, previously in the role of Technical Support Specialist, Information Technology. He has been working with the Research Information Systems team at the AHRC since June 2012 and is responsible for design and creation of electronic case report forms used for capturing clinical trial study data.</p>
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											<h2>Alice Dang</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
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						<p>Alice Dang holds a BSc in Pharmaceutical Chemistry from the University of Toronto. She joined the AHRC in 2012 as a Professional Experiential Year (PEY) intern in the role of Research Assistant, and returned full-time as a Clinical Study Assistant after the completion of her degree in 2014. Now in the role of Research Data Management Specialist, Alice is responsible for reviewing the data of a large multi-centre trial to ensure it is complete and accurate, and also provides support to project managers in the Clinical Trials Unit.</p>
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											<h2>Mohammed Hussain</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Mohammed Hussain is a Research Data Management Specialist in the Research Information Systems unit at the AHRC. His primary role consists of data management activities including data quality and reporting for both clinical trials and observational studies. Mohammed brings over five years of clinical research and management experience through cardiovascular research at St. Michael’s Hospital. He received an Hon BSc from the University of Toronto at St. George with a major in cell and molecular biology.</p>
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											<h2>Brian Kirkham</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
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						<p>Brian Kirkham, MSc, joined the Research Information Systems team as a Research Data Management Specialist in June 2016. His role at the AHRC includes both database development and research data management. Brian received his BSc and MSc in Medical Physics from Ryerson University. Prior to joining the AHRC, Brian spent two years working with the research team at the St. Michael’s Hospital Head Injury Clinic.</p>
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											<h2>Jhansi Lakshmi Saranu</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Jhansi Lakshmi Saranu, BDS, is a Certified Clinical Data Manager from the Society for Clinical Data Management with nine years of clinical data management experience. In the role of Research Data Management Specialist at the AHRC, Jhansi is responsible for development of data management plans, performing data validation activities on the electronic case report form, reviewing the data to ensure it is accurate and complete, and providing reports to sponsors and sites on validation progress. She works with the clinical team at the AHRC and also communicates with study research coordinators at sites and sponsors. Prior to joining the AHRC, Jhansi worked as a data coordinator at the Canadian Heart Research Centre, and is a dentist from NTR University of Health Sciences, India.</p>
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											<h2>Dominic Lee</h2>
					<h3>Research Quality Lead</h3>
					<h5></h5>
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						<p>Dominic Lee is the Research Quality Lead at the AHRC, responsible for leading the Research Quality &amp; Process team to ensure appropriate quality and privacy controls are developed, implemented and maintained in all the AHRC&#8217;s clinical research activities. He completed the Clinical Research postgraduate program from the Michener Institute and started at the AHRC as a volunteer in 2012. Dominic has extensive project management experience in planning, executing and delivering phase II-III multi-centre, international clinical trials in accordance with ICH-GCP, TCPS2 and applicable regulations from protocol development to publication. Dominic is an active member of the Society of Clinical Research Associates (SOCRA) and a certified Project Management Professional (PMP).</p>
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											<h2>Kaushal Pandya</h2>
					<h3>Research Compliance & Education Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Kaushal Pandya, B.Sc., ASQ CQA, CCRP has a background in Medical laboratory technology, Microbiology and Quality Assurance. Kaushal has over ten years of successful track records in Clinical Research Compliance as a QA Auditor and QA Specialist role in best managed CROs, in Research Institution at SickKids, where his contribution was Investigator Initiated Trial Management Team training and consultation, Regulatory Submission and Inspection Readiness, conducting Internal Audits and have hosted more than ten regulatory inspections including Health Canada and FDA.  With his recent successful track record at Novo nordisk pharmaceutical as an Inspection Readiness and GCP Specialist, Kaushal had successfully trained colleagues in Canada and across the globe on Health Canada Div. V, ICH-GCP, CAPA, where he has conducted onboarding, training and education sessions for the sponsor clinical development teams including CTMS, CRAs, and SCs. He also, developed an audit and inspection ready culture across all the organizations he has worked for.</p>
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