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				<div class="team-title"><span>Health Economics</span></div>
			</li>
					<li id="5">
				<a class="team">
					<span class="group-observational-epidemiology-qualitative-research"></span>
				</a>
				<div class="team-title"><span>Observational Epidemiology &amp; Qualitative Research</span></div>
			</li>
					<li id="6">
				<a class="team">
					<span class="group-biostatistics"></span>
				</a>
				<div class="team-title"><span>Biostatistics</span></div>
			</li>
					<li id="7">
				<a class="team">
					<span class="group-business-operations"></span>
				</a>
				<div class="team-title"><span>Business Operations</span></div>
			</li>
					<li id="8">
				<a class="team">
					<span class="group-research-information-systems"></span>
				</a>
				<div class="team-title"><span>Research Information Systems</span></div>
			</li>
					<li id="9">
				<a class="team">
					<span class="group-quality-assurance-monitoring"></span>
				</a>
				<div class="team-title"><span>Quality Assurance &amp; Monitoring</span></div>
			</li>
					<li id="10">
				<a class="team">
					<span class="group-knowledge-translation"></span>
				</a>
				<div class="team-title"><span>Knowledge Translation</span></div>
			</li>
			</ul>
	<hr>
</div>
	<div id="team-group-1" class="team-group">
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					Wai-Hin Chan					<span>Research Program Manager, Knowledge Translation Program</span>
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					Jhansi Lakshmi Saranu					<span>Research Data Management Specialist</span>
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					Janet Parsons					<span>Scientist</span>
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					Melissa Tom					<span>SAS Programmer / Research Data Management Specialist</span>
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					David Dai					<span>Biostatistician </span>
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					Nikita Chavda					<span>Clinical Research Specialist </span>
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					Christopher Allen					<span>Clinical Research Specialist</span>
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					Althea Ambosta Logan					<span>Research Data Management Specialist</span>
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					Andrea Tricco					<span>Scientist</span>
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					Danny Marchese					<span>Research Database Specialist </span>
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					Lisa Masucci					<span>Health Economist</span>
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					Clara Juando-Prats					<span>Clinical Research Specialist</span>
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					Lisa Johnston					<span>Manager of Research Quality & Process</span>
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					Kristin McBain					<span>Clinical Research Specialist</span>
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					Arthur S. Slutsky					<span>Vice President of Research, St. Michael’s Hospital</span>
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					Danusha Nandamalavan					<span>Clinical Research Specialist </span>
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					Brian Kirkham					<span>Research Data Management Specialist</span>
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					Christopher Ducharme					<span>Manager, Research Informatics Systems</span>
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					Dominic Lee					<span>Clinical Research Specialist</span>
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					Amr Sharaf					<span>Research Compliance and Education Specialist</span>
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					Val Panzov					<span>Clinical Research Specialist</span>
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					Melissa Giamou					<span>Clinical Research Specialist</span>
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					Allison Rau					<span>Clinical Study Assistant II</span>
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					Jeffrey S. Hoch					<span>Advisor, Centre for exceLlence in Economic Analysis Research</span>
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					Judith Hall					<span>Manager, Clinical Trials Unit</span>
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					Peter Jüni					<span>Director, Applied Health Research Centre</span>
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					Natalie Baker					<span>Clinical Research Specialist</span>
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					Deena					<span>Research Assistant</span>
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					Kari Ala-Leppilampi					<span>Clinical Research Specialist</span>
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					Magda Zaporowska					<span>Clinical Research Specialist</span>
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					Bruno da Costa					<span>Associate Director, Applied Health Research Centre </span>
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					Karen Pope					<span>Manager, Observational Epidemiology and Qualitative Research Unit</span>
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					Audra Stitt					<span>Manager, Resuscitation, Registry and Research</span>
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					Bryan Boodhoo					<span>Research Database Specialist </span>
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					Alana Harrington					<span>Clinical Research Specialist</span>
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					Shristi Bhatia					<span>Clinical Research Specialist</span>
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					Malini Handa Leno					<span>Manager of Business Operations, AHRC</span>
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					Wanrudee Isaranuwatchai					<span>Director, Centre for exceLlence in Economic Analysis Research</span>
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					Desmond Loong					<span>Research Coordinator </span>
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					Kim Phu					<span>Financial Consultant</span>
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					Kevin Thorpe					<span>Head of Biostatistics</span>
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					Karima Noordin					<span>Clinical Research Specialist </span>
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					Alice Dang					<span>Research Data Management Specialist</span>
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					Roula Raptis					<span>Clinical Research Specialist</span>
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					Srikanth Lingamaneni					<span>Research Data Management Specialist</span>
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					Cheryl Pritlove					<span>Clinical Research Specialist</span>
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					Amanda Francis					<span>Business Coordinator, AHRC</span>
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					Jessica Marchese					<span>Clinical Study Assistant II</span>
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					Isabelle Laksono					<span>Clinical Study Assistant </span>
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					Olivia Chan					<span>Clinical Research Specialist</span>
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					Kosma Wysocki					<span>Research Applications Support Specialist </span>
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					Gerald Lebovic					<span>Biostatistician</span>
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					Maria Naydenova					<span>Senior Research Database Specialist</span>
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					Pamela De Verno					<span>Senior Research Database Specialist </span>
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					Daniel Jin					<span>Clinical Research Specialist </span>
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					David Klein					<span>Head, Business Strategy and Medical Affairs</span>
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					Sharon Straus					<span>Director, Knowledge Translation Program</span>
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					Rosane Nisenbaum					<span>Associate Scientist and Biostatistician</span>
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					Arthur S. Slutsky					<span>Vice President of Research, St. Michael’s Hospital</span>
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					Sharon Straus					<span>Director, Knowledge Translation Program</span>
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					Wai-Hin Chan					<span>Research Program Manager, Knowledge Translation Program</span>
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					Christopher Ducharme					<span>Manager, Research Informatics Systems</span>
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					Judith Hall					<span>Manager, Clinical Trials Unit</span>
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					David Klein					<span>Head, Business Strategy and Medical Affairs</span>
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					Wanrudee Isaranuwatchai					<span>Director, Centre for exceLlence in Economic Analysis Research</span>
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					Peter Jüni					<span>Director, Applied Health Research Centre</span>
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					Bruno da Costa					<span>Associate Director, Applied Health Research Centre </span>
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					Karen Pope					<span>Manager, Observational Epidemiology and Qualitative Research Unit</span>
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					Olivia Chan					<span>Clinical Research Specialist</span>
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					Val Panzov					<span>Clinical Research Specialist</span>
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					Danusha Nandamalavan					<span>Clinical Research Specialist </span>
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					Jessica Marchese					<span>Clinical Study Assistant II</span>
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					Magda Zaporowska					<span>Clinical Research Specialist</span>
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					Dominic Lee					<span>Clinical Research Specialist</span>
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					Karima Noordin					<span>Clinical Research Specialist </span>
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					Kevin Thorpe					<span>Head of Biostatistics</span>
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					Shristi Bhatia					<span>Clinical Research Specialist</span>
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					Melissa Giamou					<span>Clinical Research Specialist</span>
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					Isabelle Laksono					<span>Clinical Study Assistant </span>
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					Judith Hall					<span>Manager, Clinical Trials Unit</span>
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					Nikita Chavda					<span>Clinical Research Specialist </span>
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					Deena					<span>Research Assistant</span>
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					Desmond Loong					<span>Research Coordinator </span>
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					Wanrudee Isaranuwatchai					<span>Director, Centre for exceLlence in Economic Analysis Research</span>
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					Lisa Masucci					<span>Health Economist</span>
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					Cheryl Pritlove					<span>Clinical Research Specialist</span>
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					Rosane Nisenbaum					<span>Associate Scientist and Biostatistician</span>
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					Althea Ambosta Logan					<span>Research Data Management Specialist</span>
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					Kristin McBain					<span>Clinical Research Specialist</span>
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					Alana Harrington					<span>Clinical Research Specialist</span>
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					Gerald Lebovic					<span>Biostatistician</span>
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					Karen Pope					<span>Manager, Observational Epidemiology and Qualitative Research Unit</span>
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					David Dai					<span>Biostatistician </span>
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					Natalie Baker					<span>Clinical Research Specialist</span>
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					Clara Juando-Prats					<span>Clinical Research Specialist</span>
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					Allison Rau					<span>Clinical Study Assistant II</span>
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					Roula Raptis					<span>Clinical Research Specialist</span>
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					Kari Ala-Leppilampi					<span>Clinical Research Specialist</span>
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					Janet Parsons					<span>Scientist</span>
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					Christopher Allen					<span>Clinical Research Specialist</span>
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					Gerald Lebovic					<span>Biostatistician</span>
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					Kevin Thorpe					<span>Head of Biostatistics</span>
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					Rosane Nisenbaum					<span>Associate Scientist and Biostatistician</span>
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					David Dai					<span>Biostatistician </span>
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					Amanda Francis					<span>Business Coordinator, AHRC</span>
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					Kim Phu					<span>Financial Consultant</span>
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					Malini Handa Leno					<span>Manager of Business Operations, AHRC</span>
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					</ul>
		</div>
	<div id="team-group-8" class="team-group" style="display:none">
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					<li class="noshow" data-html="#research-information-systems-christopher-ducharme">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Portraits-LKSKI-lobby-Amanda-Francis-low-res-12-of-49-1-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Christopher Ducharme					<span>Manager, Research Informatics Systems</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-kosma-wysocki">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2017/08/Portrait-20-of-78-220x220.jpg" alt="" />
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					<div class="profile-title">
					Kosma Wysocki					<span>Research Applications Support Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-dr-maria-naydenova-md">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Maria-HUB-portraits-High-Res-10-of-75-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Maria Naydenova					<span>Senior Research Database Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-bryan-boodhoo">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/no-photo-available-220x220.jpg" alt="" />
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					<div class="profile-title">
					Bryan Boodhoo					<span>Research Database Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-danny-marchese">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Danny-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Danny Marchese					<span>Research Database Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-pamela-de-verno">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Pam-220x220.jpg" alt="" />
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					<div class="profile-title">
					Pamela De Verno					<span>Senior Research Database Specialist </span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-alice-dang">
					<div class="thumb">
			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Portraits-LKSKI-lobby-Amanda-Francis-low-res-16-of-49-220x220.jpg" alt="" />
		</div>
					<div class="profile-title">
					Alice Dang					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-brian-kirkham">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/06/Portrait-17-of-78-220x220.jpg" alt="" />
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					<div class="profile-title">
					Brian Kirkham					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-srikanth-lingamaneni">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Srikanth-220x220.jpg" alt="" />
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					<div class="profile-title">
					Srikanth Lingamaneni					<span>Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-melissa-tom">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Melissa-T-220x220.jpg" alt="" />
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					<div class="profile-title">
					Melissa Tom					<span>SAS Programmer / Research Data Management Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#research-information-systems-jhansi-lakshmi-saranu">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/04/Jhansi-HUB-portraits-High-Res-29-of-75-220x220.jpg" alt="" />
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					<div class="profile-title">
					Jhansi Lakshmi Saranu					<span>Research Data Management Specialist</span>
				</div>
			</li>
					</ul>
		</div>
	<div id="team-group-9" class="team-group" style="display:none">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Amr-220x220.jpg" alt="" />
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					<div class="profile-title">
					Amr Sharaf					<span>Research Compliance and Education Specialist</span>
				</div>
			</li>
						<li class="noshow" data-html="#quality-assurance-monitoring-lisa-johnston">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/no-photo-available-220x220.jpg" alt="" />
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					<div class="profile-title">
					Lisa Johnston					<span>Manager of Research Quality & Process</span>
				</div>
			</li>
					</ul>
		</div>
	<div id="team-group-10" class="team-group" style="display:none">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Andrea-Tricco-cropped-220x220.jpg" alt="" />
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					Andrea Tricco					<span>Scientist</span>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Wai-Hin-Chan-220x220.jpg" alt="" />
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					Wai-Hin Chan					<span>Research Program Manager, Knowledge Translation Program</span>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Sharon-Straus1-220x220.jpg" alt="" />
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					<div class="profile-title">
					Sharon Straus					<span>Director, Knowledge Translation Program</span>
				</div>
			</li>
					</ul>
		</div>
</main></div></div>
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													<h2>Wai-Hin Chan</h2>
						<h3>Research Program Manager, Knowledge Translation Program</h3>
						<h5></h5>
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					<div class="bio">
						<p>Wai-Hin Chan, MBA, PT, manages the business operations for BreaKThrough Knowledge Translation Services. She holds an MBA from Wilfrid Laurier University and a Bachelor of Science in Physical Therapy (PT) from the University of Toronto. She has 20 years of experience in health care, with a recent focus and dedication on administrating projects that focus on quality improvement in health care.</p>
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													<h2>Jhansi Lakshmi Saranu</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
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						<p>Jhansi Lakshmi Saranu, BDS, is a Certified Clinical Data Manager from the Society for Clinical Data Management with nine years of clinical data management experience. In the role of Research Data Management Specialist at the AHRC, Jhansi is responsible for development of data management plans, performing data validation activities on the electronic case report form, reviewing the data to ensure it is accurate and complete, and providing reports to sponsors and sites on validation progress. She works with the clinical team at the AHRC and also communicates with study research coordinators at sites and sponsors. Prior to joining the AHRC, Jhansi worked as a data coordinator at the Canadian Heart Research Centre, and is a dentist from NTR University of Health Sciences, India.</p>
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													<h2>Janet Parsons</h2>
						<h3>Scientist</h3>
						<h5></h5>
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					<div class="bio">
						<p>Dr. Janet Parsons, PhD, is a Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital with expertise in qualitative research methods. Dr. Parsons specializes in visual and narrative methods, and is engaged in a program of film-based research. Additional research interests include health equity, oncology, knowledge translation, and health services research. A physiotherapist, Dr. Parsons practiced for 18 years in acute-care teaching hospitals and is cross-appointed to the Department of Physical Therapy, University of Toronto.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Melissa-T-220x220.jpg" alt="" />
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													<h2>Melissa Tom</h2>
						<h3>SAS Programmer / Research Data Management Specialist</h3>
						<h5></h5>
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					<div class="bio">
						<p>Melissa Tom is a SAS Programmer and Research Data Management Specialist and has been with the Research Information Systems team since December 2012. In her role at the AHRC, she is responsible for data management, data extraction and reporting of clinical data. Melissa has several years of experience using SAS.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/08/Portrait-26-of-78-220x220.jpg" alt="" />
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													<h2>David Dai</h2>
						<h3>Biostatistician </h3>
						<h5></h5>
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					<div class="bio">
						<p>David Dai received his MSc in Biostatistics and BSc (Hons.) in Pathobiology from the University of Toronto. In his current role at the AHRC, David provides statistical support for clinical trials and observational studies and analyzes data using R and SAS.</p>
<p>&nbsp;</p>
<p><span style="font-family: Calibri;"><span style="font-size: medium;"> </span></span></p>
<p>&nbsp;</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2015/09/Nikita-Sept-29-2015-e1443556176226-220x220.jpg" alt="" />
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													<h2>Nikita Chavda</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
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					<div class="bio">
						<p>Nikita Chavda, BSc, joined the AHRC as a Clinical Study Assistant in July 2015. Nikita has completed her BSc (Hons.) from the University of Toronto and has obtained a Postgraduate Diploma in Clinical Trials Management from the University of Western Ontario. Within the Clinical Trials Unit, Nikita utilizes her previous experience coordinating academic clinical trials to provide support to project managers in the operations and management of various multi-centre clinical trials.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2015/04/Chris-A-March-2015-220x220.jpg" alt="" />
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													<h2>Christopher Allen</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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					<div class="bio">
						<p>Christopher Allen, BSc, has both clinical and basic research experience. He has a BSc (Hons.) in Biochemistry and Molecular Biology and his graduate work is in cancer immunology. He has more than three years of clinical research experience in hematology/oncology. As a Clinical Research Specialist in the Observational Epidemiology and Qualitative Research Unit, Christopher oversees several projects. His roles involve study design and initiation, site management, development of case report forms and databases, data collection and quality control, research communications, and site reimbursement.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2015/04/Althea-March-2015-220x220.jpg" alt="" />
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													<h2>Althea Ambosta Logan</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p><span style="font-family: Calibri; font-size: medium;">Althea Ambosta Logan, M.A., CCRP, is a Data Management Specialist with the Research Information Systems team at the AHRC. Althea is responsible for reviewing data from multi-centre clinical trials and observational studies in Medidata RAVE and REDCap, with the goal of ensuring a high level of data quality. Althea is also involved in creating data management plans, performing validation activities on electronic case report forms and generating data management reports. Prior to her current role, Althea was a Clinical Research Specialist at the AHRC and was involved in the management and day-to-day operations of several multi-centre observational research studies. Althea holds a B.A. in Psychology from York University and an M.A. in Psychology (Brain and Cognitive Science Program) from the University of Manitoba. </span></p>
<p>&nbsp;</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Andrea-Tricco-cropped-220x220.jpg" alt="" />
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													<h2>Andrea Tricco</h2>
						<h3>Scientist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p><span style="color: #000000; font-family: Arial; font-size: medium;">Andrea Tricco completed a MSc in Epidemiology (2002-2004) and a PhD in Population Health (2005-2009). She is a Scientist in the Knowledge Translation Program of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital (appointed Sept 2011) and directs the Knowledge Synthesis Team. She is an Associate Professor at the University of Toronto in the Dalla Lana School of Public Health (appointed June 2014). Her research interests are related to responding to decision-makers (including policy-makers, healthcare providers, and patients) through knowledge synthesis. Her research also focuses on advancing the science of knowledge synthesis and she is leading research projects related to rapid reviews, network meta-analysis, and scoping reviews.</span></p>
<p><span style="color: #000000; font-family: Arial; font-size: medium;">Dr. Tricco has published over 135 peer-reviewed articles. She currently holds a Tier 2 Canada Research Chair in Knowledge Synthesis and the Ontario Ministry of Research, Innovation, and Science Early Researcher Award. She is an Associate Editor for the Journal of Clinical Epidemiology, BMC Medical Research Methodology, and Systematic Reviews; and sits on the editorial board for the BMC Medicine. She developed an online systematic review course that &gt;335 students have completed, which is offered <span style="color: #000000; font-family: Arial; font-size: medium;">through the University of Toronto.</span></span></p>
<p><span style="color: #000000; font-family: Arial; font-size: medium;"> A sample of Dr. Tricco’s publications can be found <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=tricco+a"><u>here</u></a></span></p>
<p><span style="color: #000000; font-family: Arial; font-size: medium;"> </span></p>
<p>&nbsp;</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Danny-220x220.jpg" alt="" />
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													<h2>Danny Marchese</h2>
						<h3>Research Database Specialist </h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Danny Marchese has been working with St. Michael’s Hospital since June of 2000, previously in the role of Technical Support Specialist, Information Technology. He has been working with the Research Information Systems team at the AHRC since June 2012 and is responsible for design and creation of electronic case report forms used for capturing clinical trial study data.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Portraits-LKSKI-lobby-Amanda-Francis-low-res-3-of-49-220x220.jpg" alt="" />
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													<h2>Lisa Masucci</h2>
						<h3>Health Economist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Lisa Masucci received her MSc in Health Services Research from the Institute of Health Policy, Management and Evaluation at the University of Toronto, specializing in health outcomes and evaluation. She has experience in conducting cost-effectiveness and budget impact analyses for both research and decision-making settings. She previously conducted economic analyses for the Ontario Health Technology Advisory Committee (OHTAC) and Vancouver Coastal Health. Her research interests include health technology assessment, health services outcomes and evaluation, health care priority setting and knowledge translation.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/10/Clara-220x220.jpg" alt="" />
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													<h2>Clara Juando-Prats</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Clara Juando-Prats, PhD, MSc, BScN, is a Clinical Research Specialist at the AHRC. She completed her PhD at Faculty of Nursing in the University of Toronto, her MSc at the University of Edinburgh (UK), and the BScN at the Autonomous University of Barcelona (Spain). Clara uses visual methods and critical social theory to study access and utilization to the health care resources by vulnerable populations in Toronto. Her work with young mothers with low resources, young parents living in the margins, and in partnership with community agencies, aims to positively impact the physical and mental health of this population while giving them social connections with health care providers. Prior to joining the HUB, Clara was the leader of the Knowledge Translation and Nursing Research Unit at the Hospital Sant Pau in Barcelona, developing and evaluating projects studies related to clinical safety, knowledge translation, and nursing leadership. At the Hospital Sant Pau, Clara also worked as a nurse, a research nurse, and as an specialist in qualitative methods at the Epidemiology Department. She has been collaborating for several years with the Cochrane Collaboration and the Joanna Briggs Institute as an instructor and reviewer. During 2013 and 2012 she completed two fellowships, at the Spanish Ministry of Health in qualitative research with marginalized women, and at the Centre for Global Health at the University of Ottawa in Complex Interventions and Knowledge Mobilization. The focus of Clara’s work at the AHRC has been evaluation of complex interventions, qualitative and mixed methods designs for health research, knowledge translation and health inequities.</p>
<p>&nbsp;</p>
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													<h2>Lisa Johnston</h2>
						<h3>Manager of Research Quality & Process</h3>
						<h5></h5>
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					<div class="bio">
						<p>Lisa Johnston BScN, CCRP is the Manager of Research Quality &amp; Process.</p>
<p>Lisa has over 20 years in clinical research from coordinating Phase I drug and device trials to providing education, training and support to the clinical research community at both UHN and CAMH. Lisa also writes and revises GCP courses for CITICanada and CITIUSA.</p>
<p>Lisa is responsible for developing, implementing, monitoring, and maintaining procedures, processes, and guidelines relating to the clinical research activities of the AHRC.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2015/04/Portraits-LKSKI-lobby-Amanda-Francis-low-res-47-of-49-220x220.jpg" alt="" />
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													<h2>Kristin McBain</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Kristin McBain, MSc, CCRP, PMP, has experience working in both academic and non-academic settings, and has been managing and conducting clinical research studies since 2010. She has been involved in all types of trials including bioequivalence, phase I-IV and observational research. Kristin’s clinical research experience is in the fields of neurology, oncology and pediatric critical care.</p>
<p>Kristin manages studies for both the Observational Epidemiology and Qualitative Research Unit and the Clinical Trials Unit. She is responsible for managing all aspects of each study from planning and start-up to study closure, including submitting Health Canada and ethics applications, managing stakeholders, training site coordinators, managing data and submitting progress reports to sponsors.</p>
<p>Kristin received a BSc in Biopharmaceutical Sciences, with a specialization in genomics, from the University of Ottawa and an MSc from Ryerson University, focusing on molecular imprinting of hydrogels as improved drug delivery vehicles. She is an author and co-author on several peer-reviewed abstracts and publications.</p>
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													<h2>Arthur S. Slutsky</h2>
						<h3>Vice President of Research, St. Michael’s Hospital</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Dr. Arthur S. Slutsky, MD, MASc, BASc, is the Vice President, Research, at St. Michael’s Hospital. Under his leadership, St. Michael&#8217;s has greatly expanded its research capabilities and resources and has opened its leading edge research facility, the Keenan Research Centre in the Li Ka Shing Knowledge Institute. Dr. Slutsky obtained a BASc and MASc in Engineering before graduating from Medicine at McMaster University. Subsequently, he was a pulmonary/critical care fellow and an Assistant Professor at Harvard, and returned to the University of Toronto in 1984. He has published more than 450 peer reviewed articles and his work has been cited almost 25,000 times. He has received numerous research awards and honours including the Recognition for Scientific Accomplishments Award (2005) and Critical Care Lifetime Achievement Award (2012) from the American Thoracic Society, Fellowship of Canadian Academy of Health Sciences (CAHS) (2007), Queen Elizabeth II Diamond Jubilee Medal (2012), and Honorary Member of the European Society of Intensive Care Medicine (2014). Dr. Slutsky has chaired or been a member of many Data and Safety Monitoring Boards (DSMB) and has been an advisor to the US Food and Drug Administration (FDA) on Biomedical Research, as well as chairing the FDA&#8217;s Anesthesiology and Respiratory Devices Panel for 10 years. At the University of Toronto, he was Director of the Respiratory Division for 10 years, followed by Director of the Interdepartmental Division of Critical Care Medicine for 13 years. His primary investigative areas of interest are translational research and clinical trials in intensive care and mechanical ventilation.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li><strong>Slutsky AS</strong>, Ranieri VM: Ventilator-Induced Lung Injury.  <strong>New Engl J Med</strong> 2013: 369(22): pp 2126-36. <a href="http://www.nejm.org/doi/full/10.1056/NEJMra1208707">http://www.nejm.org/doi/full/10.1056/NEJMra1208707</a></li>
<li>Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, <strong>Slutsky AS</strong>, Meade MO., for the OSCILLATE Trial Investigators and the Canadian Critical Care Trials Group: High frequency oscillation in early acute respiratory distress syndrome. <strong>New Engl J Med </strong>2013: 368(9): pp 795-805. <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1215554">http://www.nejm.org/doi/full/10.1056/NEJMoa1215554</a></li>
<li>ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND,  Caldwell E,  Fan E, Camporota L, <strong>Slutsky AS</strong>: Acute Respiratory Distress Syndrome: The Berlin Definition. <strong>JAMA</strong> 2012: 307(23): pp 2526-33. <a href="http://jama.jamanetwork.com/article.aspx?articleid=1160659">http://jama.jamanetwork.com/article.aspx?articleid=1160659</a></li>
<li>Mascia L, Pasero D, <strong>Slutsky AS</strong>, Arguis MJ, Berardino M, Grasso S, Munari M, Boifava S, Cornara G, Della Corte F, Vivaldi N, Malacarne P, Del Gaudio P, Livigni S, Zavala E, Filippini C, Martin EL, Donadio PP, Mastromauro I, Ranieri VM: Effect of a lung protective strategy for organ donors on eligibility and availability of lungs for transplantation. <strong>JAMA</strong> 2010: 304(23): pp 2620-27. <a href="http://jama.jamanetwork.com/article.aspx?articleid=187073">http://jama.jamanetwork.com/article.aspx?articleid=187073</a></li>
<li><strong>Slutsky AS</strong>: Neuromuscular blocking agents in ARDS. <strong>New Engl J Med </strong>2010: 363(12): pp 1176-80. <a href="http://www.nejm.org/doi/full/10.1056/NEJMe1007136">http://www.nejm.org/doi/full/10.1056/NEJMe1007136</a></li>
<li>Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, <strong>Slutsky AS</strong>, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM: Identification of oxidative stress and toll-like receptor 4 signalling as a key pathway of acute lung injury. <strong>Cell</strong> 2008: 133(2): pp 235-49. <a href="http://www.sciencedirect.com/science/article/pii/S0092867408003401">http://www.sciencedirect.com/science/article/pii/S0092867408003401</a></li>
<li>Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, <strong>Slutsky AS,</strong> Jian C, Penninger JM<strong>: </strong>Angiotensin-converting enzyme 2 protects from severe acute lung failure. <strong> Nature</strong> 2005: 436(7047): pp 112-6. <a href="http://www.nature.com/nature/journal/v436/n7047/abs/nature03712.html">http://www.nature.com/nature/journal/v436/n7047/abs/nature03712.html</a></li>
<li><strong>Slutsky AS</strong>, Lavery JV: Data safety and monitoring boards.  <strong>New Engl J Med </strong>2004: 350(11): pp 1143-1147.  <a href="http://www.nejm.org/doi/full/10.1056/NEJMsb033476">http://www.nejm.org/doi/full/10.1056/NEJMsb033476</a></li>
<li>Imai Y, Parodo J, Kajikawa O, de Perrot M, Fischer S, Edwards V, Cutz E, Liu M, Keshavjee S, Martin TR, Marshall JC, Ranieri VM, <strong>Slutsky</strong> <strong>AS</strong>: Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome, (2003), 289 <strong>JAMA</strong>, pp.2104-2112. <a href="http://jama.jamanetwork.com/article.aspx?articleid=196447">http://jama.jamanetwork.com/article.aspx?articleid=196447</a></li>
<li>Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, Stewart TE, Barr A, Cook D, <strong>Slutsky AS</strong> for the Canadian Critical Care Trials Group: One-year outcomes in survivors of the acute respiratory distress syndrome. <strong>New Engl J Med</strong> 2003: 348(8): pp 683-693. <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa022450">http://www.nejm.org/doi/full/10.1056/NEJMoa022450</a></li>
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													<h2>Danusha Nandamalavan</h2>
						<h3>Clinical Research Specialist </h3>
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						<p><span style="font-family: Calibri; font-size: medium;">Danusha Nandamalavan, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides support in the planning and management of multi-centre randomized clinical trials. Danusha has experience working in both academic and non-academic settings, and has been involved in all types of trials. Danusha is an active member of the Society of Clinical Research Associates (SOCRA).</span></p>
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													<h2>Brian Kirkham</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
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						<p>Brian Kirkham, MSc, joined the Research Information Systems team as a Research Data Management Specialist in June 2016. His role at the AHRC includes both database development and research data management. Brian received his BSc and MSc in Medical Physics from Ryerson University. Prior to joining the AHRC, Brian spent two years working with the research team at the St. Michael’s Hospital Head Injury Clinic.</p>
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													<h2>Christopher Ducharme</h2>
						<h3>Manager, Research Informatics Systems</h3>
						<h5></h5>
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						<p>Chris Ducharme, MSc, BSc, is the Manager of the Research Information Systems unit at the AHRC. He manages core electronic data capture systems, which includes administration, programming and liaison with Information Technology. Chris has experience working in different software development and Information Technology support roles with the Ontario Government and as the Research Application Support Specialist with the AHRC. He holds an MSc in Computer Security from the University of Liverpool and a BSc in Computer Engineering from the University of Ottawa.</p>
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													<h2>Dominic Lee</h2>
						<h3>Clinical Research Specialist</h3>
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						<p>Dominic Lee, BSc, CCRP, joined the AHRC in 2012 as a volunteer and is now employed full-time with the Clinical Trials Unit. He has a background in biology and completed a Postgraduate Certificate in Clinical Research from the Michener Institute. Dominic provides administrative support in the planning and management of multi-centre randomized clinical trials, including regulatory submissions, site communications, study operations, and supply management.</p>
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													<h2>Amr Sharaf</h2>
						<h3>Research Compliance and Education Specialist</h3>
						<h5></h5>
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						<p>Amr Sharaf, BSc, CCRP, has a background in biochemistry and over four years of experience performing monitoring and quality control of academic and industry-driven clinical trials. He previously worked at the Ottawa Hospital Research Institute as the institutional Clinical Research Monitor and Facilitator providing trial management and quality improvement support to over thirty clinical trials. In his role as a Research Compliance and Education Specialist, Amr provides monitoring services and guidance to clinical trial sites in addition to implementing educational initiatives aimed toward improving overall clinical trial conduct.</p>
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													<h2>Val Panzov</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Dr. Val Panzov, MD, has more than 15 years of extensive clinical research experience as well as comprehensive clinical background. Prior to joining the Clinical Trials Unit in 2008, Dr. Panzov worked in various positions managing clinical operations, R&amp;D and business development in pharmaceutical and academic settings. As a Clinical Research Specialist, Val oversees multi-centre clinical trials and is responsible for clinical trials development in a broad range of therapeutic areas.</p>
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													<h2>Melissa Giamou</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Melissa Giamou has a BSc (Hons.) in Biology from the University of Western Ontario, and joined AHRC in 2013 through an internship for a Postgraduate Diploma in Clinical Trials Management. Melissa oversees multi-centre randomized clinical trials, particularly in the therapeutic areas of cardiology and medical devices. In her role as a Clinical Research Specialist, Melissa coordinates electronic case report form development, oversees data collection and safety reporting, creates and maintains essential project documents, helps manage study budgets, payments and contracts, along with conducting other operational activities.</p>
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													<h2>Allison Rau</h2>
						<h3>Clinical Study Assistant II</h3>
						<h5></h5>
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						<p><span style="color: #000000; font-family: Calibri; font-size: medium;"> <span style="color: #000000; font-family: Calibri; font-size: medium;">Allison Rau, MSc., is a Clinical Study Assistant with the Observational, Epidemiology and Qualitative Research Unit. She is responsible for coordinating and assisting multiple studies with patient enrolment, day-to-day site duties and study completion. Her past experience includes clinical research in pediatrics and geriatric psychiatry, particularly in the area of Alzheimer’s prevention in a population of clinically depressed and cognitively impaired seniors, where she has peer-authored several publications. Allison received her MSc. in Applied Clinical Pharmacology from the University of Toronto and her BSc. in Biological Sciences from the University of Calgary. </span></span></p>
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													<h2>Jeffrey S. Hoch</h2>
						<h3>Advisor, Centre for exceLlence in Economic Analysis Research</h3>
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						<p>Dr. Jeffrey Hoch received his PhD in Health Economics from the Johns Hopkins School of Public Health. He also holds an MS in Economics from Johns Hopkins University and a BA in Quantitative Economics and Decision Sciences from the University of California at San Diego. An award winning teacher, Dr. Hoch has taught health economics and economic evaluation courses in Canada, the United States, and internationally. He is dedicated to research, capacity building and knowledge transfer related to health economics. His research focuses on health economics methods and making health economics more useful to decision makers.</p>
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													<h2>Judith Hall</h2>
						<h3>Manager, Clinical Trials Unit</h3>
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						<p>Judith Hall, MSc, CCRP, PMP is the Manager of the Clinical Trials Unit, and is responsible for oversight of all clinical trials being managed by AHRC. She has been managing research teams and supervising trial monitors and operational staff for over 10 years. Prior to joining the AHRC in 2008, Judith worked in the pharmaceutical and CRO industries as a clinical trials project manager and clinical data manager. She has extensive trial management experience in Canadian and multi-national trials, and in many therapeutic areas including neurology, psychiatry, oncology, respiratory and gastroenterology. She holds an MSc in Pharmacology from the University of Toronto and a BSc in Biochemistry from McGill.</p>
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													<h2>Peter Jüni</h2>
						<h3>Director, Applied Health Research Centre</h3>
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						<p>Dr. Peter Jüni, MD, FESC, is the Director of the AHRC at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and a Professor at the Department of Medicine and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He is a graduate of the Faculty of Medicine at the University of Bern in Switzerland, completed his training in internal medicine at various hospitals in Switzerland, and was a Research Fellow at the Department of Social Medicine at the University of Bristol, UK. Prior to joining St. Michael’s Hospital, Dr. Jüni was the Director of the Institute of Primary Health Care and Professor of Primary Care and Clinical Epidemiology at the Faculty of Medicine at the University of Bern in Switzerland. He held previous appointments as Director of the Institute of Social and Preventive Medicine at the University of Bern and Founding Director of CTU Bern, the University’s clinical trials unit.</p>
<p>Dr. Jüni is internationally renowned for his methodological work and for his clinical research on the management of cardiovascular and musculoskeletal disorders. A Fellow of the European Society of Cardiology, he has had leading roles in several major cardiovascular trials, including SIRTAX, LEADERS, FAME 2 and MATRIX, served as a member of several task forces of the European Society of Cardiology, and co-authored the European guidelines on myocardial revascularization and on the management of acute myocardial infarction. Dr. Jüni has published over 270 papers, many of these widely cited. In 2015 he was recognized as Highly Cited Researcher by Thomson Reuters in view of several papers published in the last decade that ranked among the top 1% most cited in their field.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li>da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, <u>Jüni P</u>, Trelle S. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. <strong>Lancet</strong>. 2016 Mar 17. [Epub ahead of print]. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/26997557" target="_blank">26997557</a>.</li>
<li>Valgimigli M, Gagnor A, Calabró P, Frigoli E, Leonardi S, Zaro T, Rubartelli P, Briguori C, Andò G, Repetto A, Limbruno U, Cortese B, Sganzerla P, Lupi A, Galli M, Colangelo S, Ierna S, Ausiello A, Presbitero P, Sardella G, Varbella F, Esposito G, Santarelli A, Tresoldi S, Nazzaro M, Zingarelli A, de Cesare N, Rigattieri S, Tosi P, Palmieri C, Brugaletta S, Rao SV, Heg D, Rothenbühler M, Vranckx P, <u>Jüni P</u>. Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial. <strong>Lancet</strong>. 2015 Jun 20. 385(9986): 2465-76. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25791214" target="_blank">25791214</a>.</li>
<li>Biller-Andorno N, <u>Jüni P</u>. Abolishing mammography screening programs? A view from the Swiss Medical Board. <strong>N Engl J Med</strong>. 2014 May 22. 370(21): 1965-7. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/24738641" target="_blank">24738641</a>.</li>
<li>De Bruyne B, Fearon WF, Pijls NH, Barbato E, Tonino P, Piroth Z, Jagic N, Mobius-Winckler S, Rioufol G, Witt N, Kala P, MacCarthy P, Engström T, Oldroyd K, Mavromatis K, Manoharan G, Verlee P, Frobert O, Curzen N, Johnson JB, Limacher A, Nüesch E, <u>Jüni P</u>. Fractional flow reserve-guided PCI for stable coronary artery disease. <strong>N Engl J Med</strong>. 2014 Sep 25. 371(13):1208-17. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25176289" target="_blank">25176289</a>.</li>
<li>Stefanini GG, Kalesan B, Serruys PW, Heg D, Buszman P, Linke A, Ischinger T, Klauss V, Eberli F, Wijns W, Morice MC, Di Mario C, Corti R, Antoni D, Sohn HY, Eerdmans P, van Es GA, Meier B, Windecker S, <u>Jüni P</u>. Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. <strong>Lancet</strong>. 2011 Dec 3. 378(9807):1940-8. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/22075451" target="_blank">22075451</a>.</li>
<li>Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, Egger M, <u>Jüni P</u>. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. <strong>BMJ</strong>. 2011 Jan 11. 342: 342:c7086. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/21224324" target="_blank">21224324</a>.</li>
<li>Nüesch E, Trelle S, Reichenbach S, Rutjes AW, Tschannen B, Altman DG, Egger M, <u>Jüni P</u>. Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study. <strong>BMJ</strong>. 2010 Jul 16. 341:c3515. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20639294" target="_blank">20639294</a>.</li>
<li>Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schömig A, Pfisterer ME, Stone GW, Leon MB, Suarez de Lezo J, Goy JJ, Park SJ, Sabaté M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, <u>Jüni P</u>. Outcomes associated with drug-eluting and bare-metal stents: A collaborative network meta-analysis. <strong>Lancet</strong>. 2007 Sep 15. 370(9591):937–48. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17869634" target="_blank">17869634</a>.</li>
<li>Reichenbach S, Sterchi R, Scherer M, Trelle S, Bürgi E, Bürgi U, Dieppe P, <u>Jüni P</u>. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. <strong>Ann Intern Med</strong>. 2007 Apr 17. 146(8):580-90. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17438317" target="_blank">17438317</a>.</li>
<li><u>Jüni P</u>, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. <strong>Lancet</strong>. 2004 Dec 4-10. 364(9450):2021-9. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/15582059" target="_blank">15582059</a>.</li>
<li><u>Jüni P</u>, Altman DG, Egger M. Assessing the quality of controlled clinical trials. <strong>BMJ</strong>. 2001 Jul 7. 323(7303):42-6. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/11440947" target="_blank">11440947</a>.</li>
<li><u>Jüni P</u>, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. <strong>JAMA</strong>. 1999 Sep 15. 282(11):1054-60. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/10493204" target="_blank">10493204</a>.</li>
</ol>
<p>To view more of Dr. Jüni’s publications, go to <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=juni+p" target="_blank">PubMed</a>.</p>
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													<h2>Natalie Baker</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Natalie Baker, MSc, PhD(c), is a Clinical Research Specialist at the HUB focusing on qualitative research, health services and health equity. She works on interdisciplinary teams and has contributed to dozens of studies and initiatives from local to international. She is also a doctoral student at the School of Public Health at the University of Toronto, under the supervision of Katherine Boydell (University of Toronto, SickKids and Black Dog Institute) where she is focusing on creative approaches in youth mental health.</p>
<p>Natalie graduated with Great Distinction from McGill University with her BA in Psychology and Behavioural Sciences. She was a student in Donald Taylor&#8217;s Intergroup Relations and Aboriginal Peoples group where she conducted her final year project on understanding the impact of collective guilt using survey and implicit association lab testing techniques. She also completed a year-long advanced student field placement in a psychiatric ward and provided a creative outlet for children in treatment across Montreal hospitals. She went on to pursue political and critical psychology at the London School of Economics and was supervised by Derek Hook for her MSc dissertation in the Department of Social Psychology.</p>
<p>Natalie has been rooted in a creative learning environment and continues to be inspired by the arts as a powerful form of expression. She is involved in knowledge creation and dissemination strategies using the arts, media and community-based approaches, as well as being a co-author on traditional peer-reviewed publications and teaching in university and hospital settings.</p>
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													<h2>Deena</h2>
						<h3>Research Assistant</h3>
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						<p>Deena, M.B.B.S., is a Research Assistant at the CLEAR. Her role encompasses taking care of the administrative processes of the organization and assisting the Principal Investigator with ongoing research activities including the submissions of REB applications, grants, and manuscripts, conducting literature reviews, and performing data analyses. She recently completed the Internationally Trained Medical Doctors (ITMD) Bridging Program at Ryerson University, where she gained exposure in Health Informatics, Communication and Leadership skills, Research Methodologies, and Project Management. As an internationally trained medical graduate, she has a strong clinical background from her experience working in the Family Medicine and Community Health fields.</p>
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													<h2>Kari Ala-Leppilampi</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Kari Ala-leppilampi received a Master of Planning (MPl) degree from Ryerson University’s School of Regional and Urban Planning and an MSc in Health Promotion from the Dalla Lana School of Public Health, University of Toronto. Through his graduate level training and employment in both urban planning and public health research, Kari brings a broad base of knowledge to his role at AHRC, and a uniquely valuable multidisciplinary perspective. While his specialty is qualitative inquiry, Kari is also well versed in quantitative and mixed methods approaches, and has taught courses on research theory and methods. His research has focused on a wide range of issues including outcomes associated with illicit drug policy, criminal justice diversion programs, mental health and addiction treatment services, and policies in relation to the provision of affordable and supportive housing. In keeping with his personal interest in physical activity, his research has also focused on the social benefits of active transportation, and the potential role of exercise and sport in recovery from mental health and addiction issues. As a Clinical Research Specialist, Kari focuses on qualitative, health services research by coordinating research studies, and conducting qualitative interviews and analysis on a range of health related interventions.</p>
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													<h2>Magda Zaporowska</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Magda Zaporowska, BSc, is a Clinical Research Specialist in the Clinical Trials Unit and is responsible for the day-to-day management of multi-centre randomized clinical trials. Her role involves protocol and electronic case report form development, site management, overseeing data collection, communications, management of study budgets, payments and contracts, and other operational activities. Magda completed her BSc (Hons.) in Biology and Biological Anthropology from the University of Toronto and obtained a Postgraduate Certificate in Clinical Research from Humber College. Prior to joining the AHRC, Magda worked for five years with a Research Ethics Board reviewing a wide range of multidisciplinary study and oncology trial submissions.</p>
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													<h2>Bruno da Costa</h2>
						<h3>Associate Director, Applied Health Research Centre </h3>
						<h5></h5>
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						<p>Dr. Bruno R. da Costa is the Associate Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute at St. Michael&#8217;s Hospital, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation of the University of Toronto. Dr. da Costa has a PhD in Clinical Epidemiology and Biostatistics from the University of Bern in Switzerland and a Master of Science degree in Physical Therapy from the University of Alberta. He is currently completing a Master of Science in Medical Statistics, with a focus on Bayesian statistics, from the University of Leicester, United Kingdom. Before joining the AHRC, Dr. da Costa was the Head of Statistics and Methodology of the Department of Cardiology as well as the Head of Clinical Research of the Institute of Primary Health Care, both at the University of Bern. Previous appointments include Assistant Professor at the Department of Physical Therapy, and Adjunct Professor at the Department of Health Policy &amp; Management, both at Florida International University.</p>
<p>Dr. da Costa has published over seventy peer-reviewed articles and is known for his clinical research on musculoskeletal and cardiovascular conditions and for his methodological research on comparative effectiveness.</p>
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													<h2>Karen Pope</h2>
						<h3>Manager, Observational Epidemiology and Qualitative Research Unit</h3>
						<h5></h5>
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						<p>Karen Pope, MSc, MA, CCRP, is the Manager of the Observational Epidemiology and Qualitative Research Unit of the AHRC. Karen has more than eight years of clinical research experience as well as extensive experience in basic science research, project management, and education. She is responsible for the oversight of observational and qualitative research studies as well as the planning and operations of patient registries.</p>
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													<h2>Audra Stitt</h2>
						<h3>Manager, Resuscitation, Registry and Research</h3>
						<h5></h5>
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						<p><span style="font-family: Calibri; font-size: medium;">Audra Stitt, MSc is the Manager, Resuscitation, Registry and Research. Audra has more than 14 years of experience with public health research, population and cohort based observation studies and clinical trials and has been managing research teams since 2010. She has extensive experience with data abstraction (in both prehospital and hospital settings), large administrative data sets and project management. Audra is responsible for the oversight of R3DB as well as other research databases for prehospital and critical care research.</span></p>
<p>&nbsp;</p>
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													<h2>Bryan Boodhoo</h2>
						<h3>Research Database Specialist </h3>
						<h5></h5>
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						<p>Bryan Boodhoo, MSc, has more than 20 years of clinical trials research experience, predominantly in the pharmaceutical industry. He works with the Research Information Systems team as an expert in Clinical Data Programming with thorough technical understanding in the design, setup and validation of databases, creating edit checks, data extraction and transformation, and generating formatted reports and listings using SAS, RAVE, Oracle Clinical or INFORM.</p>
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													<h2>Alana Harrington</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Alana Harrington obtained an MSc in Epidemiology from York University after she received her BSc (Hons.) from the University of Toronto with a double major in Biology and Biological Anthropology. She has been a St. Michael&#8217;s employee for over 15 years and has been involved in several different research areas including animal studies, randomized clinical trials, and observational projects that focused on improving the health of cardiac surgery patients. In her role as a Clinical Research Specialist, Alana is involved in the design, development and management of research projects in the Observational Epidemiology and Qualitative Research Unit.</p>
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													<h2>Shristi Bhatia</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Shristi Bhatia, BSc, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials. Shristi began her career in clinical research in 2009, working as a project lead for Electronic Data Capturing Company, responsible for designing and building electronic case report forms.  She has worked in a variety of research areas including medical device, dermatology, Dupuytren&#8217;s disease, brain aneurysm, and hand and foot disease.  She has also worked as a clinical research coordinator for several industry sponsored clinical trials focusing on various stages of prostate cancer. Shristi has a BSc from University of Toronto and a Postgraduate Certificate in Clinical Research from Humber College. She is an active member of the Society of Clinical Research Associates (SOCRA) and has maintained her certification as a Clinical Research Professional since 2011.</p>
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													<h2>Malini Handa Leno</h2>
						<h3>Manager of Business Operations, AHRC</h3>
						<h5></h5>
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						<p>Malini Handa Leno, MSc, MBA, PMP, is the Manager, Business Operations, and is accountable for financial, human resource, and contract management at the AHRC. Malini joined the AHRC with 15 years of experience in the pharmaceutical, CRO, and hospital sectors. Her previous roles have focused on clinical trial management, patient safety and risk management, and most recently, the implementation of information management systems to help transform health care. Malini holds an MBA from the Desautels Faculty of Management at McGill University, and an MSc in Pharmacology from Dalhousie University.</p>
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													<h2>Wanrudee Isaranuwatchai</h2>
						<h3>Director, Centre for exceLlence in Economic Analysis Research</h3>
						<h5></h5>
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						<p>Dr. Wanrudee Isaranuwatchai is the Director of the CLEAR at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. She is also a Research Scientist at St. Michael&#8217;s Hospital, a Health Economist at the Canadian Centre for Applied Research in Cancer Control, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation, University of Toronto. She received her PhD in Health Services Research, specializing in Health Economics, from the University of Toronto.</p>
<p>Dr. Isaranuwatchai has collaborated with researchers and decision-makers in various topics areas across disciplines to help communicate the value of health programs/innovations using economic evidence. She has experience conducting economic evaluations using person-level data and decision modeling. Dr. Isaranuwatchai’s research focuses on applied economic evaluation (e.g., how to make economic evaluation more useful to researchers, health providers, and policy-makers in the real-world context) and health economics methods.</p>
<p>To view Dr. Isaranuwatchai&#8217;s publications, please go to <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=isaranuwatchai+w">PubMed</a>.</p>
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													<h2>Desmond Loong</h2>
						<h3>Research Coordinator </h3>
						<h5></h5>
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						<p>Desmond Loong holds an HBSc specializing in Human Biology from the University of Toronto and is currently completing his MSc in Health Services Research at the University’s Institute of Health Policy Management and Evaluation (IHPME). Specializing in health outcomes and evaluation, Desmond also has experience in mental health research, program evaluations, systematic literature reviews, database management, and data analysis using SPSS.</p>
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													<h2>Kim Phu</h2>
						<h3>Financial Consultant</h3>
						<h5></h5>
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						<p>Kim Phu, BA, CPA, CGA, has more than ten years of accounting experience, working in the areas of market research, structural engineering and for the not-for-profit sector. As the Financial Consultant at the AHRC, Kim is responsible for the day-to-day financial management of multi-million dollar project budgets and to support the Manager, Business Operations (AHRC) and others.</p>
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													<h2>Kevin Thorpe</h2>
						<h3>Head of Biostatistics</h3>
						<h5></h5>
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						<p>Kevin Thorpe, MMath, has over 20 years of experience in clinical research as a biostatistician and methodologist. He is currently an Assistant Professor in the Dalla Lana School of Public Health at the University of Toronto and is Head of Biostatistics and a methodologist with the AHRC, where he specializes in clinical trials.</p>
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													<h2>Karima Noordin</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
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						<p>Karima Noordin, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides administrative support in the planning and management of multi-centre randomized clinical trials. Karima has experience working in both academic and non-academic settings, and has been involved in all types of trials, including bioequivalence, phase I-IV and observational research. Karima is an active member of the Society of Clinical Research Associates (SOCRA).</p>
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													<h2>Alice Dang</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
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						<p>Alice Dang holds a BSc in Pharmaceutical Chemistry from the University of Toronto. She joined the AHRC in 2012 as a Professional Experiential Year (PEY) intern in the role of Research Assistant, and returned full-time as a Clinical Study Assistant after the completion of her degree in 2014. Now in the role of Research Data Management Specialist, Alice is responsible for reviewing the data of a large multi-centre trial to ensure it is complete and accurate, and also provides support to project managers in the Clinical Trials Unit.</p>
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													<h2>Roula Raptis</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Roula (Stavroula) Raptis, MSc, has a diverse research background and interests, lending well to her analytical skills and ability to work with multi-disciplinary teams. Roula completed her BSc at the University of Waterloo, with a focus in cell and molecular biology and microbiology. She went on to complete an MSc degree at the University of Toronto in the Department of Laboratory Medicine and Pathobiology. There she explored gene polymorphisms in cancer susceptibility genes and was a member of a large, nationally funded initiative &#8211; the interprovincial Colorectal Cancer Interdisciplinary Health Research Team. Roula has experience in both academic and nonacademic settings, including working for an independent analytical laboratory for several years, as well as in various teaching environments. In her current role with the Observational Epidemiology and Qualitative Research Unit, Roula is involved in study design, patient registry and database design, protocol and data collection form development, study planning and operations, and research communications. She is the author of a book chapter on genetic instability, and an author and co-author on several additional peer-reviewed publications.</p>
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													<h2>Srikanth Lingamaneni</h2>
						<h3>Research Data Management Specialist</h3>
						<h5></h5>
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						<p>Srikanth Lingamaneni, BDS, PGDCR, has more than seven years of clinical data management experience.  He is responsible for the development of data management plans and data entry guidelines, providing training to site personnel on web-based electronic case report forms (eCRFs), performing testing and data validation activities on the eCRF, reviewing data to ensure it is complete and accurate, creating and running reports on data entry and validation progress, and supporting the clinical team with data management activities. Prior to joining the Research Information Systems team, Shrikanth worked for pharmaceutical and clinical research organizations as a data manager and study designer. He is a dentist from Rajiv Gandhi University of Health Sciences, Bangalore, India.</p>
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													<h2>Cheryl Pritlove</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p>Cheryl Pritlove, PhD, is a Clinical Research Specialist, employing qualitative methods to the study of a variety of health-related research topics, including cardiac health and diabetes. She has extensive experience and expertise in qualitative and arts-based methods, health policy, and psychosocial oncology. Cheryl has a BA in Health and Society and an MSc in Kinesiology and Health Science from York University. She conducted her doctoral research at the Princess Margaret Cancer Centre where she worked with patients as well as health care and service providers to identify gaps in the delivery of cancer care and explored innovative approaches to (acute/chronic) care integration.  She has conducted health services research with a number of organizations including Wellspring, ELLICSR Health, Wellness and Cancer Survivorship Centre, as well as the University of Toronto and York University.</p>
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													<h2>Amanda Francis</h2>
						<h3>Business Coordinator, AHRC</h3>
						<h5></h5>
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						<p>Amanda Francis has a BSc in Business Administration Human Resources Management from Wayne State University and over three years of Human Resource experience in various industries. As the Business Coordinator, Amanda looks after various employee inquiries, coordinates projects, manages internal websites, and assists with modifying Human Resources procedures within the office.</p>
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													<h2>Jessica Marchese</h2>
						<h3>Clinical Study Assistant II</h3>
						<h5></h5>
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						<p>Jessica Marchese, BSc, joined the AHRC&#8217;s CTU team as a Clinical Study Assistant II in July 2017. Jessica received her BSc from the University of Toronto, focusing on human biology and physiology. She also completed a post-graduate Clinical Research Certificate Program from the Michener Institute. She has previous experience in coordinating surgical oncology clinical trails, as well as qualitative studies. At AHRC, Jessica utilizes her previous experience in order to support project managers with the day-to-day management of clinical trials and general study administrative support.</p>
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<p><span style="font-family: 'Calibri Light','sans-serif'; font-size: 10.5pt;"><span style="color: #000000;"> </span></span></p>
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													<h2>Isabelle Laksono</h2>
						<h3>Clinical Study Assistant </h3>
						<h5></h5>
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						<p><span style="color: #000000; font-family: Calibri; font-size: medium;">Isabelle Laksono is a Clinical Study Assistant in the Clinical Trials Unit. She received her Honors Bachelor of Science in Pharmacology at the University of Toronto. In her role as a CSA, Isabelle provides administrative support in the planning and management of multi-centre randomized clinical trials, by maintaining study master files, preparing and distributing study documents and supplies, tracking study progress, reviewing data, performing data validation, and coordinating study meetings.</span></p>
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													<h2>Olivia Chan</h2>
						<h3>Clinical Research Specialist</h3>
						<h5></h5>
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						<p><span style="color: #000000; font-family: Calibri; font-size: medium;">Olivia Chan, M.Sc., PMP, is a Clinical Research Specialist with the Clinical Trials Unit, and is responsible for the coordination and management of randomized clinical trials. Her role involves managing all aspects of each study from planning and start-up to study closure.  Olivia brings with her more than 10 years of scientific research experience in immunology and oncology, and has authored several peer-reviewed publications. Olivia received her M.Sc. in Immunology from the University of Toronto after receiving her B.Sc. (Honors) in Biology and Psychology from McMaster University.  </span></p>
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													<h2>Kosma Wysocki</h2>
						<h3>Research Applications Support Specialist </h3>
						<h5></h5>
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						<p>Kosma Wysocki, B.Sc. Supports the AHRC’s applications through regular system and database administration and maintenance activities as well as performing custom development work as required. Kosma brings over five years of experience in technical support and systems administration experience to the AHRC.</p>
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													<h2>Gerald Lebovic</h2>
						<h3>Biostatistician</h3>
						<h5></h5>
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						<p>Dr. Gerald Lebovic received an MSc in Statistics and a PhD in Biostatistics from the University of Toronto. He has 10 years of experience working on observational studies and has consulted on a variety of studies in the medical field. Currently, Gerald is a biostatistician at the HUB and an Assistant Professor at the Institute of Health Policy, Management and Evaluation at the University of Toronto. Gerald works with numerous researchers from various disciplines on a variety of observational studies. His research interests include health services research, longitudinal data analysis, observational studies and multi-state models.</p>
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													<h2>Maria Naydenova</h2>
						<h3>Senior Research Database Specialist</h3>
						<h5></h5>
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						<p>Dr. Maria Naydenova, MD, has more than 15 years of clinical research experience and a strong clinical background. She received an MD in Plovdiv Medical University, Bulgaria. As a Research Database Specialist at the AHRC, Maria is responsible for the design, build, and support of clinical studies in various electronic data capture systems. Prior to joining the Research Information Systems team in 2010, Maria worked in pharmaceutical industries and health care sectors monitoring sites and overseeing clinical trial data for national and international clinical trials.</p>
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													<h2>Pamela De Verno</h2>
						<h3>Senior Research Database Specialist </h3>
						<h5></h5>
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						<p>Pamela De Verno, MSc, has over 15 years of clinical research experience, as well as extensive experience in biotechnology research and development. As a Research Database Specialist with the Research Information Systems team, Pamela is responsible for the design, build and support of studies within a data management system for storage, validation and retrieval of clinical data.</p>
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													<h2>Daniel Jin</h2>
						<h3>Clinical Research Specialist </h3>
						<h5></h5>
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						<p><span style="font-family: Calibri; font-size: medium;">Daniel Jin is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for the coordination and management of randomized clinical trials. Daniel holds a BSc in Biology and Psychology from the University of Toronto and a Postgraduate Certificate in Clinical Research from Humber College. Prior to joining the AHRC, Daniel worked in the Office of Research Administration at St. Michael’s Hospital and has been involved in research operations at different levels in both industry and academic settings.</span></p>
<p>&nbsp;</p>
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													<h2>David Klein</h2>
						<h3>Head, Business Strategy and Medical Affairs</h3>
						<h5></h5>
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						<p>Dr. David Klein, MD, MBA, is Head of Medical Affairs and Business Strategy for the AHRC. He is responsible for AHRC’s business strategy including partnerships and alliances as well as medical affairs and medical oversight of the AHRC. Dr. Klein trained in Internal Medicine and Critical Care Medicine at the University of Toronto and completed his MBA at the Kellogg School of Management. Before returning to medicine he was a consultant at McKinsey &amp; Company where he was a founding member of the Canadian Healthcare Practice and served as an advisor in therapeutic area strategy to several large pharmaceutical companies. He has also been involved in medical affairs for the last 10 years for Canadian biotechnology firms and has contributed to clinical trial development, clinical trial oversight, Health Canada and US Food and Drug Administration (FDA) regulatory submissions including 510K and Premarket Approval Application (PMA). Dr. Klein is also active in research in biomarkers in critical care and has published and presented his work internationally.</p>
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													<h2>Sharon Straus</h2>
						<h3>Director, Knowledge Translation Program</h3>
						<h5></h5>
					</div>
					<div class="bio">
						<p>Dr. Sharon Straus, MD, FRCPC, MSc, HBSc, oversees all projects conducted by BreaKThrough in her capacity as the director of the Knowledge Translation Program. She is also a scientist and a geriatrician at St. Michael’s Hospital. Dr. Straus is a Professor in the Department of Medicine, and Division Director of Geriatric Medicine, both at the University of Toronto. She is the Co-Director of the Knowledge Translation Canada program as well as the Director of the Knowledge Translation Canada Strategic Training Initiative in Health Research program. She has more than 300 publications and is also the co-author of three textbooks including, ‘Evidence-based Medicine: How to practice and teach it’ and ‘Knowledge Translation in Health Care.’ The former has been published in nine languages and is currently in its fourth edition. It has been used in education curricula worldwide including undergraduate, postgraduate and continuing education courses. She holds a Tier 1 Canada Research Chair in Knowledge Translation and Quality of Care. Dr. Straus is an international leader in knowledge translation research and practice, a distinguished educator, and a skilled mentor.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li>Tricco AC, Ashoor HM, Antony J, Beyene J, Veroniki AA, Isaranuwatchai W, Harrington A, Wilson C, Tsoursos S, Soobiah C, Yu CH, Hutton B, Hoch JS, Hemmelgarn BR, Moher D, Majumdar S, <strong>Straus SE</strong>. Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic review and network meta-analysis. BMJ. 2014 Oct. 1;349:g5459. <strong>Senior Responsible Author.</strong></li>
<li>Tricco AC, Antony J, Ivers NM, Ashoor HM, Khan PA, Blondal E, Ghassemi M, MacDonald H, Chen MH, Ezer LK, <strong>Straus SE</strong>. Effectiveness of quality improvement strategies for coordination of care to reduce use of health care services: a systematic review and meta-analysis. CMAJ. 2014 Sep. [Epub ahead of print]. <strong>Senior Responsible Author.</strong></li>
<li>Wilcox E, Chong C, Stanbrook M, Tricco AC, Wong C, <strong>Straus SE</strong>. Does This Patient Have An Exudative Pleural Effusion? How Do I Perform A Thoracentesis And Analyze The Results. JAMA. 2014 Jun. ;311(23):2422-2431. <strong>Senior Responsible Author.</strong></li>
<li>Kwan E, <strong>Straus SE</strong>. Assessment and Management of Falls in Older People. CMAJ. 2014 Jun. 30 [Epub ahead of print] (Trainee publication). <strong>Senior Responsible Author.</strong></li>
<li>Stelfox HT, Cameron P, Fortin MC, Francescutti L, Kenneth J, Kmetik K, Kortbeek J, Nathens A, Phan N, Singleton B, Travers A, Zygun D, Noseworthy T, <strong>Straus SE</strong>. Development and Evaluation of Evidence-Informed Quality Indicators for Adult Injury Care. Ann Surg. 2013 May 7 [Epub ahead of print]. <strong>Senior Responsible Author.</strong></li>
<li>Brouwers M, Thabane L, Moher D, <strong>Straus SE</strong>. Comparative Effectiveness Research Paradigm: Implications for Systematic Reviews and Clinical Practice Guidelines. J Clin Oncol. 2012 Dec 1; 30(34): 4202-4207. <strong>Senior Responsible Author.</strong></li>
<li>Yu Ch, Bahniwal R, Laupacis A, Leung E, Orr MS, <strong>Straus SE</strong>. Systematic review and evaluation of web-accessible tools for management of diabetes and related cardiovascular risk factors by patients and healthcare providers. J AM Med Inform Assoc. 2012 Jul-Aug;19(4):514-22. <strong>Senior Responsible</strong> <strong>Author.</strong></li>
<li>Wong C, Holroyd-Leduc J, Simel DL, <strong>Straus SE</strong>. Does this patient have delirium? Value of bedside instruments. JAMA 2010 Aug 18;304(7):779-86. <strong>Senior Responsible Author.</strong></li>
<li>Sambunjak D, <strong>Straus SE</strong>, Marusic A. Mentoring in academic medicine: A systematic review. JAMA 2006;296(9):1103-15. <strong>Senior Responsible Author</strong>.</li>
<li>Holroyd-Leduc J, <strong>Straus SE</strong>. Management of urinary incontinence in women:  Systematic review. JAMA 2004;291(8):986-95. (Trainee publication, Mentor to Dr. Holroyd-Leduc). <strong>Senior Responsible Author</strong>.</li>
<li>Holroyd-Leduc J, <strong>Straus SE</strong>. Management of urinary incontinence in women:  Clinical applications. JAMA 2004;291(8):996-9. (Trainee publication, Mentor to Dr. Holroyd-Leduc). <strong>Senior Responsible Author</strong>.</li>
<li><strong>Straus SE</strong>, Green M, Bell DS, Badgett R, Davis D, Gerrity M, Ortiz E, Shaneyfelt TM, Whelan C, Mangrulkar R, on behalf of the SGIM EBM Task Force. Evaluating the teaching of evidence based medicine: conceptual framework. BMJ 2004;329(7473):1029-1032. <strong>Principal Author</strong>.</li>
</ol>
<p>To view more of Dr. Straus&#8217;s publications, go to <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=Sharon+Straus" target="_blank">PubMed</a>.</p>
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													<h2>Rosane Nisenbaum</h2>
						<h3>Associate Scientist and Biostatistician</h3>
						<h5></h5>
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						<p>Dr. Rosane Nisenbaum, PhD, has special interest in multi-level models, longitudinal and categorical data analysis and multiple imputation applied to neighborhood effects on mental health, and homelessness and housing studies. She provides assistance in the design and analysis of studies conducted by St. Michael’s investigators, fellows and students and is a member of St. Michael’s Research Ethics Board. Dr. Nisenbaum is an Assistant Professor in the Division of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, co-teaching the course ‘Laboratory in Statistical Design &amp; Analysis’ and serving as a Practicum supervisor.</p>
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											<h2>Arthur S. Slutsky</h2>
					<h3>Vice President of Research, St. Michael’s Hospital</h3>
					<h5></h5>
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						<p>Dr. Arthur S. Slutsky, MD, MASc, BASc, is the Vice President, Research, at St. Michael’s Hospital. Under his leadership, St. Michael&#8217;s has greatly expanded its research capabilities and resources and has opened its leading edge research facility, the Keenan Research Centre in the Li Ka Shing Knowledge Institute. Dr. Slutsky obtained a BASc and MASc in Engineering before graduating from Medicine at McMaster University. Subsequently, he was a pulmonary/critical care fellow and an Assistant Professor at Harvard, and returned to the University of Toronto in 1984. He has published more than 450 peer reviewed articles and his work has been cited almost 25,000 times. He has received numerous research awards and honours including the Recognition for Scientific Accomplishments Award (2005) and Critical Care Lifetime Achievement Award (2012) from the American Thoracic Society, Fellowship of Canadian Academy of Health Sciences (CAHS) (2007), Queen Elizabeth II Diamond Jubilee Medal (2012), and Honorary Member of the European Society of Intensive Care Medicine (2014). Dr. Slutsky has chaired or been a member of many Data and Safety Monitoring Boards (DSMB) and has been an advisor to the US Food and Drug Administration (FDA) on Biomedical Research, as well as chairing the FDA&#8217;s Anesthesiology and Respiratory Devices Panel for 10 years. At the University of Toronto, he was Director of the Respiratory Division for 10 years, followed by Director of the Interdepartmental Division of Critical Care Medicine for 13 years. His primary investigative areas of interest are translational research and clinical trials in intensive care and mechanical ventilation.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li><strong>Slutsky AS</strong>, Ranieri VM: Ventilator-Induced Lung Injury.  <strong>New Engl J Med</strong> 2013: 369(22): pp 2126-36. <a href="http://www.nejm.org/doi/full/10.1056/NEJMra1208707">http://www.nejm.org/doi/full/10.1056/NEJMra1208707</a></li>
<li>Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, <strong>Slutsky AS</strong>, Meade MO., for the OSCILLATE Trial Investigators and the Canadian Critical Care Trials Group: High frequency oscillation in early acute respiratory distress syndrome. <strong>New Engl J Med </strong>2013: 368(9): pp 795-805. <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1215554">http://www.nejm.org/doi/full/10.1056/NEJMoa1215554</a></li>
<li>ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND,  Caldwell E,  Fan E, Camporota L, <strong>Slutsky AS</strong>: Acute Respiratory Distress Syndrome: The Berlin Definition. <strong>JAMA</strong> 2012: 307(23): pp 2526-33. <a href="http://jama.jamanetwork.com/article.aspx?articleid=1160659">http://jama.jamanetwork.com/article.aspx?articleid=1160659</a></li>
<li>Mascia L, Pasero D, <strong>Slutsky AS</strong>, Arguis MJ, Berardino M, Grasso S, Munari M, Boifava S, Cornara G, Della Corte F, Vivaldi N, Malacarne P, Del Gaudio P, Livigni S, Zavala E, Filippini C, Martin EL, Donadio PP, Mastromauro I, Ranieri VM: Effect of a lung protective strategy for organ donors on eligibility and availability of lungs for transplantation. <strong>JAMA</strong> 2010: 304(23): pp 2620-27. <a href="http://jama.jamanetwork.com/article.aspx?articleid=187073">http://jama.jamanetwork.com/article.aspx?articleid=187073</a></li>
<li><strong>Slutsky AS</strong>: Neuromuscular blocking agents in ARDS. <strong>New Engl J Med </strong>2010: 363(12): pp 1176-80. <a href="http://www.nejm.org/doi/full/10.1056/NEJMe1007136">http://www.nejm.org/doi/full/10.1056/NEJMe1007136</a></li>
<li>Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, <strong>Slutsky AS</strong>, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM: Identification of oxidative stress and toll-like receptor 4 signalling as a key pathway of acute lung injury. <strong>Cell</strong> 2008: 133(2): pp 235-49. <a href="http://www.sciencedirect.com/science/article/pii/S0092867408003401">http://www.sciencedirect.com/science/article/pii/S0092867408003401</a></li>
<li>Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, <strong>Slutsky AS,</strong> Jian C, Penninger JM<strong>: </strong>Angiotensin-converting enzyme 2 protects from severe acute lung failure. <strong> Nature</strong> 2005: 436(7047): pp 112-6. <a href="http://www.nature.com/nature/journal/v436/n7047/abs/nature03712.html">http://www.nature.com/nature/journal/v436/n7047/abs/nature03712.html</a></li>
<li><strong>Slutsky AS</strong>, Lavery JV: Data safety and monitoring boards.  <strong>New Engl J Med </strong>2004: 350(11): pp 1143-1147.  <a href="http://www.nejm.org/doi/full/10.1056/NEJMsb033476">http://www.nejm.org/doi/full/10.1056/NEJMsb033476</a></li>
<li>Imai Y, Parodo J, Kajikawa O, de Perrot M, Fischer S, Edwards V, Cutz E, Liu M, Keshavjee S, Martin TR, Marshall JC, Ranieri VM, <strong>Slutsky</strong> <strong>AS</strong>: Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome, (2003), 289 <strong>JAMA</strong>, pp.2104-2112. <a href="http://jama.jamanetwork.com/article.aspx?articleid=196447">http://jama.jamanetwork.com/article.aspx?articleid=196447</a></li>
<li>Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, Stewart TE, Barr A, Cook D, <strong>Slutsky AS</strong> for the Canadian Critical Care Trials Group: One-year outcomes in survivors of the acute respiratory distress syndrome. <strong>New Engl J Med</strong> 2003: 348(8): pp 683-693. <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa022450">http://www.nejm.org/doi/full/10.1056/NEJMoa022450</a></li>
</ol>
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											<h2>Sharon Straus</h2>
					<h3>Director, Knowledge Translation Program</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Sharon Straus, MD, FRCPC, MSc, HBSc, oversees all projects conducted by BreaKThrough in her capacity as the director of the Knowledge Translation Program. She is also a scientist and a geriatrician at St. Michael’s Hospital. Dr. Straus is a Professor in the Department of Medicine, and Division Director of Geriatric Medicine, both at the University of Toronto. She is the Co-Director of the Knowledge Translation Canada program as well as the Director of the Knowledge Translation Canada Strategic Training Initiative in Health Research program. She has more than 300 publications and is also the co-author of three textbooks including, ‘Evidence-based Medicine: How to practice and teach it’ and ‘Knowledge Translation in Health Care.’ The former has been published in nine languages and is currently in its fourth edition. It has been used in education curricula worldwide including undergraduate, postgraduate and continuing education courses. She holds a Tier 1 Canada Research Chair in Knowledge Translation and Quality of Care. Dr. Straus is an international leader in knowledge translation research and practice, a distinguished educator, and a skilled mentor.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li>Tricco AC, Ashoor HM, Antony J, Beyene J, Veroniki AA, Isaranuwatchai W, Harrington A, Wilson C, Tsoursos S, Soobiah C, Yu CH, Hutton B, Hoch JS, Hemmelgarn BR, Moher D, Majumdar S, <strong>Straus SE</strong>. Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic review and network meta-analysis. BMJ. 2014 Oct. 1;349:g5459. <strong>Senior Responsible Author.</strong></li>
<li>Tricco AC, Antony J, Ivers NM, Ashoor HM, Khan PA, Blondal E, Ghassemi M, MacDonald H, Chen MH, Ezer LK, <strong>Straus SE</strong>. Effectiveness of quality improvement strategies for coordination of care to reduce use of health care services: a systematic review and meta-analysis. CMAJ. 2014 Sep. [Epub ahead of print]. <strong>Senior Responsible Author.</strong></li>
<li>Wilcox E, Chong C, Stanbrook M, Tricco AC, Wong C, <strong>Straus SE</strong>. Does This Patient Have An Exudative Pleural Effusion? How Do I Perform A Thoracentesis And Analyze The Results. JAMA. 2014 Jun. ;311(23):2422-2431. <strong>Senior Responsible Author.</strong></li>
<li>Kwan E, <strong>Straus SE</strong>. Assessment and Management of Falls in Older People. CMAJ. 2014 Jun. 30 [Epub ahead of print] (Trainee publication). <strong>Senior Responsible Author.</strong></li>
<li>Stelfox HT, Cameron P, Fortin MC, Francescutti L, Kenneth J, Kmetik K, Kortbeek J, Nathens A, Phan N, Singleton B, Travers A, Zygun D, Noseworthy T, <strong>Straus SE</strong>. Development and Evaluation of Evidence-Informed Quality Indicators for Adult Injury Care. Ann Surg. 2013 May 7 [Epub ahead of print]. <strong>Senior Responsible Author.</strong></li>
<li>Brouwers M, Thabane L, Moher D, <strong>Straus SE</strong>. Comparative Effectiveness Research Paradigm: Implications for Systematic Reviews and Clinical Practice Guidelines. J Clin Oncol. 2012 Dec 1; 30(34): 4202-4207. <strong>Senior Responsible Author.</strong></li>
<li>Yu Ch, Bahniwal R, Laupacis A, Leung E, Orr MS, <strong>Straus SE</strong>. Systematic review and evaluation of web-accessible tools for management of diabetes and related cardiovascular risk factors by patients and healthcare providers. J AM Med Inform Assoc. 2012 Jul-Aug;19(4):514-22. <strong>Senior Responsible</strong> <strong>Author.</strong></li>
<li>Wong C, Holroyd-Leduc J, Simel DL, <strong>Straus SE</strong>. Does this patient have delirium? Value of bedside instruments. JAMA 2010 Aug 18;304(7):779-86. <strong>Senior Responsible Author.</strong></li>
<li>Sambunjak D, <strong>Straus SE</strong>, Marusic A. Mentoring in academic medicine: A systematic review. JAMA 2006;296(9):1103-15. <strong>Senior Responsible Author</strong>.</li>
<li>Holroyd-Leduc J, <strong>Straus SE</strong>. Management of urinary incontinence in women:  Systematic review. JAMA 2004;291(8):986-95. (Trainee publication, Mentor to Dr. Holroyd-Leduc). <strong>Senior Responsible Author</strong>.</li>
<li>Holroyd-Leduc J, <strong>Straus SE</strong>. Management of urinary incontinence in women:  Clinical applications. JAMA 2004;291(8):996-9. (Trainee publication, Mentor to Dr. Holroyd-Leduc). <strong>Senior Responsible Author</strong>.</li>
<li><strong>Straus SE</strong>, Green M, Bell DS, Badgett R, Davis D, Gerrity M, Ortiz E, Shaneyfelt TM, Whelan C, Mangrulkar R, on behalf of the SGIM EBM Task Force. Evaluating the teaching of evidence based medicine: conceptual framework. BMJ 2004;329(7473):1029-1032. <strong>Principal Author</strong>.</li>
</ol>
<p>To view more of Dr. Straus&#8217;s publications, go to <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=Sharon+Straus" target="_blank">PubMed</a>.</p>
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											<h2>Wai-Hin Chan</h2>
					<h3>Research Program Manager, Knowledge Translation Program</h3>
					<h5></h5>
					<div class="bio">
						<p>Wai-Hin Chan, MBA, PT, manages the business operations for BreaKThrough Knowledge Translation Services. She holds an MBA from Wilfrid Laurier University and a Bachelor of Science in Physical Therapy (PT) from the University of Toronto. She has 20 years of experience in health care, with a recent focus and dedication on administrating projects that focus on quality improvement in health care.</p>
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											<h2>Christopher Ducharme</h2>
					<h3>Manager, Research Informatics Systems</h3>
					<h5></h5>
					<div class="bio">
						<p>Chris Ducharme, MSc, BSc, is the Manager of the Research Information Systems unit at the AHRC. He manages core electronic data capture systems, which includes administration, programming and liaison with Information Technology. Chris has experience working in different software development and Information Technology support roles with the Ontario Government and as the Research Application Support Specialist with the AHRC. He holds an MSc in Computer Security from the University of Liverpool and a BSc in Computer Engineering from the University of Ottawa.</p>
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											<h2>Judith Hall</h2>
					<h3>Manager, Clinical Trials Unit</h3>
					<h5></h5>
					<div class="bio">
						<p>Judith Hall, MSc, CCRP, PMP is the Manager of the Clinical Trials Unit, and is responsible for oversight of all clinical trials being managed by AHRC. She has been managing research teams and supervising trial monitors and operational staff for over 10 years. Prior to joining the AHRC in 2008, Judith worked in the pharmaceutical and CRO industries as a clinical trials project manager and clinical data manager. She has extensive trial management experience in Canadian and multi-national trials, and in many therapeutic areas including neurology, psychiatry, oncology, respiratory and gastroenterology. She holds an MSc in Pharmacology from the University of Toronto and a BSc in Biochemistry from McGill.</p>
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											<h2>David Klein</h2>
					<h3>Head, Business Strategy and Medical Affairs</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. David Klein, MD, MBA, is Head of Medical Affairs and Business Strategy for the AHRC. He is responsible for AHRC’s business strategy including partnerships and alliances as well as medical affairs and medical oversight of the AHRC. Dr. Klein trained in Internal Medicine and Critical Care Medicine at the University of Toronto and completed his MBA at the Kellogg School of Management. Before returning to medicine he was a consultant at McKinsey &amp; Company where he was a founding member of the Canadian Healthcare Practice and served as an advisor in therapeutic area strategy to several large pharmaceutical companies. He has also been involved in medical affairs for the last 10 years for Canadian biotechnology firms and has contributed to clinical trial development, clinical trial oversight, Health Canada and US Food and Drug Administration (FDA) regulatory submissions including 510K and Premarket Approval Application (PMA). Dr. Klein is also active in research in biomarkers in critical care and has published and presented his work internationally.</p>
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											<h2>Wanrudee Isaranuwatchai</h2>
					<h3>Director, Centre for exceLlence in Economic Analysis Research</h3>
					<h5></h5>
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						<p>Dr. Wanrudee Isaranuwatchai is the Director of the CLEAR at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. She is also a Research Scientist at St. Michael&#8217;s Hospital, a Health Economist at the Canadian Centre for Applied Research in Cancer Control, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation, University of Toronto. She received her PhD in Health Services Research, specializing in Health Economics, from the University of Toronto.</p>
<p>Dr. Isaranuwatchai has collaborated with researchers and decision-makers in various topics areas across disciplines to help communicate the value of health programs/innovations using economic evidence. She has experience conducting economic evaluations using person-level data and decision modeling. Dr. Isaranuwatchai’s research focuses on applied economic evaluation (e.g., how to make economic evaluation more useful to researchers, health providers, and policy-makers in the real-world context) and health economics methods.</p>
<p>To view Dr. Isaranuwatchai&#8217;s publications, please go to <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=isaranuwatchai+w">PubMed</a>.</p>
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											<h2>Malini Handa Leno</h2>
					<h3>Manager of Business Operations, AHRC</h3>
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						<p>Malini Handa Leno, MSc, MBA, PMP, is the Manager, Business Operations, and is accountable for financial, human resource, and contract management at the AHRC. Malini joined the AHRC with 15 years of experience in the pharmaceutical, CRO, and hospital sectors. Her previous roles have focused on clinical trial management, patient safety and risk management, and most recently, the implementation of information management systems to help transform health care. Malini holds an MBA from the Desautels Faculty of Management at McGill University, and an MSc in Pharmacology from Dalhousie University.</p>
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											<h2>Peter Jüni</h2>
					<h3>Director, Applied Health Research Centre</h3>
					<h5></h5>
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						<p>Dr. Peter Jüni, MD, FESC, is the Director of the AHRC at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and a Professor at the Department of Medicine and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He is a graduate of the Faculty of Medicine at the University of Bern in Switzerland, completed his training in internal medicine at various hospitals in Switzerland, and was a Research Fellow at the Department of Social Medicine at the University of Bristol, UK. Prior to joining St. Michael’s Hospital, Dr. Jüni was the Director of the Institute of Primary Health Care and Professor of Primary Care and Clinical Epidemiology at the Faculty of Medicine at the University of Bern in Switzerland. He held previous appointments as Director of the Institute of Social and Preventive Medicine at the University of Bern and Founding Director of CTU Bern, the University’s clinical trials unit.</p>
<p>Dr. Jüni is internationally renowned for his methodological work and for his clinical research on the management of cardiovascular and musculoskeletal disorders. A Fellow of the European Society of Cardiology, he has had leading roles in several major cardiovascular trials, including SIRTAX, LEADERS, FAME 2 and MATRIX, served as a member of several task forces of the European Society of Cardiology, and co-authored the European guidelines on myocardial revascularization and on the management of acute myocardial infarction. Dr. Jüni has published over 270 papers, many of these widely cited. In 2015 he was recognized as Highly Cited Researcher by Thomson Reuters in view of several papers published in the last decade that ranked among the top 1% most cited in their field.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li>da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, <u>Jüni P</u>, Trelle S. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. <strong>Lancet</strong>. 2016 Mar 17. [Epub ahead of print]. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/26997557" target="_blank">26997557</a>.</li>
<li>Valgimigli M, Gagnor A, Calabró P, Frigoli E, Leonardi S, Zaro T, Rubartelli P, Briguori C, Andò G, Repetto A, Limbruno U, Cortese B, Sganzerla P, Lupi A, Galli M, Colangelo S, Ierna S, Ausiello A, Presbitero P, Sardella G, Varbella F, Esposito G, Santarelli A, Tresoldi S, Nazzaro M, Zingarelli A, de Cesare N, Rigattieri S, Tosi P, Palmieri C, Brugaletta S, Rao SV, Heg D, Rothenbühler M, Vranckx P, <u>Jüni P</u>. Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial. <strong>Lancet</strong>. 2015 Jun 20. 385(9986): 2465-76. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25791214" target="_blank">25791214</a>.</li>
<li>Biller-Andorno N, <u>Jüni P</u>. Abolishing mammography screening programs? A view from the Swiss Medical Board. <strong>N Engl J Med</strong>. 2014 May 22. 370(21): 1965-7. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/24738641" target="_blank">24738641</a>.</li>
<li>De Bruyne B, Fearon WF, Pijls NH, Barbato E, Tonino P, Piroth Z, Jagic N, Mobius-Winckler S, Rioufol G, Witt N, Kala P, MacCarthy P, Engström T, Oldroyd K, Mavromatis K, Manoharan G, Verlee P, Frobert O, Curzen N, Johnson JB, Limacher A, Nüesch E, <u>Jüni P</u>. Fractional flow reserve-guided PCI for stable coronary artery disease. <strong>N Engl J Med</strong>. 2014 Sep 25. 371(13):1208-17. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/25176289" target="_blank">25176289</a>.</li>
<li>Stefanini GG, Kalesan B, Serruys PW, Heg D, Buszman P, Linke A, Ischinger T, Klauss V, Eberli F, Wijns W, Morice MC, Di Mario C, Corti R, Antoni D, Sohn HY, Eerdmans P, van Es GA, Meier B, Windecker S, <u>Jüni P</u>. Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. <strong>Lancet</strong>. 2011 Dec 3. 378(9807):1940-8. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/22075451" target="_blank">22075451</a>.</li>
<li>Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, Egger M, <u>Jüni P</u>. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. <strong>BMJ</strong>. 2011 Jan 11. 342: 342:c7086. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/21224324" target="_blank">21224324</a>.</li>
<li>Nüesch E, Trelle S, Reichenbach S, Rutjes AW, Tschannen B, Altman DG, Egger M, <u>Jüni P</u>. Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study. <strong>BMJ</strong>. 2010 Jul 16. 341:c3515. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20639294" target="_blank">20639294</a>.</li>
<li>Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schömig A, Pfisterer ME, Stone GW, Leon MB, Suarez de Lezo J, Goy JJ, Park SJ, Sabaté M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, <u>Jüni P</u>. Outcomes associated with drug-eluting and bare-metal stents: A collaborative network meta-analysis. <strong>Lancet</strong>. 2007 Sep 15. 370(9591):937–48. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17869634" target="_blank">17869634</a>.</li>
<li>Reichenbach S, Sterchi R, Scherer M, Trelle S, Bürgi E, Bürgi U, Dieppe P, <u>Jüni P</u>. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. <strong>Ann Intern Med</strong>. 2007 Apr 17. 146(8):580-90. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/17438317" target="_blank">17438317</a>.</li>
<li><u>Jüni P</u>, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. <strong>Lancet</strong>. 2004 Dec 4-10. 364(9450):2021-9. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/15582059" target="_blank">15582059</a>.</li>
<li><u>Jüni P</u>, Altman DG, Egger M. Assessing the quality of controlled clinical trials. <strong>BMJ</strong>. 2001 Jul 7. 323(7303):42-6. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/11440947" target="_blank">11440947</a>.</li>
<li><u>Jüni P</u>, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. <strong>JAMA</strong>. 1999 Sep 15. 282(11):1054-60. PubMed PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/10493204" target="_blank">10493204</a>.</li>
</ol>
<p>To view more of Dr. Jüni’s publications, go to <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=juni+p" target="_blank">PubMed</a>.</p>
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											<h2>Bruno da Costa</h2>
					<h3>Associate Director, Applied Health Research Centre </h3>
					<h5></h5>
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						<p>Dr. Bruno R. da Costa is the Associate Director of the Applied Health Research Centre (AHRC) at the Li Ka Shing Knowledge Institute at St. Michael&#8217;s Hospital, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation of the University of Toronto. Dr. da Costa has a PhD in Clinical Epidemiology and Biostatistics from the University of Bern in Switzerland and a Master of Science degree in Physical Therapy from the University of Alberta. He is currently completing a Master of Science in Medical Statistics, with a focus on Bayesian statistics, from the University of Leicester, United Kingdom. Before joining the AHRC, Dr. da Costa was the Head of Statistics and Methodology of the Department of Cardiology as well as the Head of Clinical Research of the Institute of Primary Health Care, both at the University of Bern. Previous appointments include Assistant Professor at the Department of Physical Therapy, and Adjunct Professor at the Department of Health Policy &amp; Management, both at Florida International University.</p>
<p>Dr. da Costa has published over seventy peer-reviewed articles and is known for his clinical research on musculoskeletal and cardiovascular conditions and for his methodological research on comparative effectiveness.</p>
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											<h2>Karen Pope</h2>
					<h3>Manager, Observational Epidemiology and Qualitative Research Unit</h3>
					<h5></h5>
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						<p>Karen Pope, MSc, MA, CCRP, is the Manager of the Observational Epidemiology and Qualitative Research Unit of the AHRC. Karen has more than eight years of clinical research experience as well as extensive experience in basic science research, project management, and education. She is responsible for the oversight of observational and qualitative research studies as well as the planning and operations of patient registries.</p>
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											<h2>Daniel Jin</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
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						<p><span style="font-family: Calibri; font-size: medium;">Daniel Jin is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for the coordination and management of randomized clinical trials. Daniel holds a BSc in Biology and Psychology from the University of Toronto and a Postgraduate Certificate in Clinical Research from Humber College. Prior to joining the AHRC, Daniel worked in the Office of Research Administration at St. Michael’s Hospital and has been involved in research operations at different levels in both industry and academic settings.</span></p>
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											<h2>Olivia Chan</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
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						<p><span style="color: #000000; font-family: Calibri; font-size: medium;">Olivia Chan, M.Sc., PMP, is a Clinical Research Specialist with the Clinical Trials Unit, and is responsible for the coordination and management of randomized clinical trials. Her role involves managing all aspects of each study from planning and start-up to study closure.  Olivia brings with her more than 10 years of scientific research experience in immunology and oncology, and has authored several peer-reviewed publications. Olivia received her M.Sc. in Immunology from the University of Toronto after receiving her B.Sc. (Honors) in Biology and Psychology from McMaster University.  </span></p>
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											<h2>Val Panzov</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Val Panzov, MD, has more than 15 years of extensive clinical research experience as well as comprehensive clinical background. Prior to joining the Clinical Trials Unit in 2008, Dr. Panzov worked in various positions managing clinical operations, R&amp;D and business development in pharmaceutical and academic settings. As a Clinical Research Specialist, Val oversees multi-centre clinical trials and is responsible for clinical trials development in a broad range of therapeutic areas.</p>
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											<h2>Danusha Nandamalavan</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p><span style="font-family: Calibri; font-size: medium;">Danusha Nandamalavan, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides support in the planning and management of multi-centre randomized clinical trials. Danusha has experience working in both academic and non-academic settings, and has been involved in all types of trials. Danusha is an active member of the Society of Clinical Research Associates (SOCRA).</span></p>
<p>&nbsp;</p>
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											<h2>Jessica Marchese</h2>
					<h3>Clinical Study Assistant II</h3>
					<h5></h5>
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						<p>Jessica Marchese, BSc, joined the AHRC&#8217;s CTU team as a Clinical Study Assistant II in July 2017. Jessica received her BSc from the University of Toronto, focusing on human biology and physiology. She also completed a post-graduate Clinical Research Certificate Program from the Michener Institute. She has previous experience in coordinating surgical oncology clinical trails, as well as qualitative studies. At AHRC, Jessica utilizes her previous experience in order to support project managers with the day-to-day management of clinical trials and general study administrative support.</p>
<p>&nbsp;</p>
<p><span style="font-family: 'Calibri Light','sans-serif'; font-size: 10.5pt;"><span style="color: #000000;"> </span></span></p>
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											<h2>Magda Zaporowska</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
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						<p>Magda Zaporowska, BSc, is a Clinical Research Specialist in the Clinical Trials Unit and is responsible for the day-to-day management of multi-centre randomized clinical trials. Her role involves protocol and electronic case report form development, site management, overseeing data collection, communications, management of study budgets, payments and contracts, and other operational activities. Magda completed her BSc (Hons.) in Biology and Biological Anthropology from the University of Toronto and obtained a Postgraduate Certificate in Clinical Research from Humber College. Prior to joining the AHRC, Magda worked for five years with a Research Ethics Board reviewing a wide range of multidisciplinary study and oncology trial submissions.</p>
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											<h2>Dominic Lee</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
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						<p>Dominic Lee, BSc, CCRP, joined the AHRC in 2012 as a volunteer and is now employed full-time with the Clinical Trials Unit. He has a background in biology and completed a Postgraduate Certificate in Clinical Research from the Michener Institute. Dominic provides administrative support in the planning and management of multi-centre randomized clinical trials, including regulatory submissions, site communications, study operations, and supply management.</p>
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											<h2>Karima Noordin</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
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						<p>Karima Noordin, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials, including regulatory submissions, site communications, study operations and supply management. She provides administrative support in the planning and management of multi-centre randomized clinical trials. Karima has experience working in both academic and non-academic settings, and has been involved in all types of trials, including bioequivalence, phase I-IV and observational research. Karima is an active member of the Society of Clinical Research Associates (SOCRA).</p>
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											<h2>Kevin Thorpe</h2>
					<h3>Head of Biostatistics</h3>
					<h5></h5>
					<div class="bio">
						<p>Kevin Thorpe, MMath, has over 20 years of experience in clinical research as a biostatistician and methodologist. He is currently an Assistant Professor in the Dalla Lana School of Public Health at the University of Toronto and is Head of Biostatistics and a methodologist with the AHRC, where he specializes in clinical trials.</p>
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											<h2>Shristi Bhatia</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
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						<p>Shristi Bhatia, BSc, CCRP, is a Clinical Research Specialist with the Clinical Trials Unit and is responsible for day-to-day management of various aspects of clinical trials. Shristi began her career in clinical research in 2009, working as a project lead for Electronic Data Capturing Company, responsible for designing and building electronic case report forms.  She has worked in a variety of research areas including medical device, dermatology, Dupuytren&#8217;s disease, brain aneurysm, and hand and foot disease.  She has also worked as a clinical research coordinator for several industry sponsored clinical trials focusing on various stages of prostate cancer. Shristi has a BSc from University of Toronto and a Postgraduate Certificate in Clinical Research from Humber College. She is an active member of the Society of Clinical Research Associates (SOCRA) and has maintained her certification as a Clinical Research Professional since 2011.</p>
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											<h2>Melissa Giamou</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Melissa Giamou has a BSc (Hons.) in Biology from the University of Western Ontario, and joined AHRC in 2013 through an internship for a Postgraduate Diploma in Clinical Trials Management. Melissa oversees multi-centre randomized clinical trials, particularly in the therapeutic areas of cardiology and medical devices. In her role as a Clinical Research Specialist, Melissa coordinates electronic case report form development, oversees data collection and safety reporting, creates and maintains essential project documents, helps manage study budgets, payments and contracts, along with conducting other operational activities.</p>
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											<h2>Isabelle Laksono</h2>
					<h3>Clinical Study Assistant </h3>
					<h5></h5>
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						<p><span style="color: #000000; font-family: Calibri; font-size: medium;">Isabelle Laksono is a Clinical Study Assistant in the Clinical Trials Unit. She received her Honors Bachelor of Science in Pharmacology at the University of Toronto. In her role as a CSA, Isabelle provides administrative support in the planning and management of multi-centre randomized clinical trials, by maintaining study master files, preparing and distributing study documents and supplies, tracking study progress, reviewing data, performing data validation, and coordinating study meetings.</span></p>
<p>&nbsp;</p>
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		</div>
											<h2>Judith Hall</h2>
					<h3>Manager, Clinical Trials Unit</h3>
					<h5></h5>
					<div class="bio">
						<p>Judith Hall, MSc, CCRP, PMP is the Manager of the Clinical Trials Unit, and is responsible for oversight of all clinical trials being managed by AHRC. She has been managing research teams and supervising trial monitors and operational staff for over 10 years. Prior to joining the AHRC in 2008, Judith worked in the pharmaceutical and CRO industries as a clinical trials project manager and clinical data manager. She has extensive trial management experience in Canadian and multi-national trials, and in many therapeutic areas including neurology, psychiatry, oncology, respiratory and gastroenterology. She holds an MSc in Pharmacology from the University of Toronto and a BSc in Biochemistry from McGill.</p>
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											<h2>Nikita Chavda</h2>
					<h3>Clinical Research Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Nikita Chavda, BSc, joined the AHRC as a Clinical Study Assistant in July 2015. Nikita has completed her BSc (Hons.) from the University of Toronto and has obtained a Postgraduate Diploma in Clinical Trials Management from the University of Western Ontario. Within the Clinical Trials Unit, Nikita utilizes her previous experience coordinating academic clinical trials to provide support to project managers in the operations and management of various multi-centre clinical trials.</p>
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											<h2>Deena</h2>
					<h3>Research Assistant</h3>
					<h5></h5>
					<div class="bio">
						<p>Deena, M.B.B.S., is a Research Assistant at the CLEAR. Her role encompasses taking care of the administrative processes of the organization and assisting the Principal Investigator with ongoing research activities including the submissions of REB applications, grants, and manuscripts, conducting literature reviews, and performing data analyses. She recently completed the Internationally Trained Medical Doctors (ITMD) Bridging Program at Ryerson University, where she gained exposure in Health Informatics, Communication and Leadership skills, Research Methodologies, and Project Management. As an internationally trained medical graduate, she has a strong clinical background from her experience working in the Family Medicine and Community Health fields.</p>
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											<h2>Desmond Loong</h2>
					<h3>Research Coordinator </h3>
					<h5></h5>
					<div class="bio">
						<p>Desmond Loong holds an HBSc specializing in Human Biology from the University of Toronto and is currently completing his MSc in Health Services Research at the University’s Institute of Health Policy Management and Evaluation (IHPME). Specializing in health outcomes and evaluation, Desmond also has experience in mental health research, program evaluations, systematic literature reviews, database management, and data analysis using SPSS.</p>
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											<h2>Wanrudee Isaranuwatchai</h2>
					<h3>Director, Centre for exceLlence in Economic Analysis Research</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Wanrudee Isaranuwatchai is the Director of the CLEAR at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. She is also a Research Scientist at St. Michael&#8217;s Hospital, a Health Economist at the Canadian Centre for Applied Research in Cancer Control, and an Assistant Professor at the Institute of Health Policy, Management and Evaluation, University of Toronto. She received her PhD in Health Services Research, specializing in Health Economics, from the University of Toronto.</p>
<p>Dr. Isaranuwatchai has collaborated with researchers and decision-makers in various topics areas across disciplines to help communicate the value of health programs/innovations using economic evidence. She has experience conducting economic evaluations using person-level data and decision modeling. Dr. Isaranuwatchai’s research focuses on applied economic evaluation (e.g., how to make economic evaluation more useful to researchers, health providers, and policy-makers in the real-world context) and health economics methods.</p>
<p>To view Dr. Isaranuwatchai&#8217;s publications, please go to <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=isaranuwatchai+w">PubMed</a>.</p>
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					<div style="display:none" id="health-economics-jeffrey-s-hoch-phd">
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											<h2>Jeffrey S. Hoch</h2>
					<h3>Advisor, Centre for exceLlence in Economic Analysis Research</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Jeffrey Hoch received his PhD in Health Economics from the Johns Hopkins School of Public Health. He also holds an MS in Economics from Johns Hopkins University and a BA in Quantitative Economics and Decision Sciences from the University of California at San Diego. An award winning teacher, Dr. Hoch has taught health economics and economic evaluation courses in Canada, the United States, and internationally. He is dedicated to research, capacity building and knowledge transfer related to health economics. His research focuses on health economics methods and making health economics more useful to decision makers.</p>
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					<div style="display:none" id="health-economics-lisa-masucci-msc">
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											<h2>Lisa Masucci</h2>
					<h3>Health Economist</h3>
					<h5></h5>
					<div class="bio">
						<p>Lisa Masucci received her MSc in Health Services Research from the Institute of Health Policy, Management and Evaluation at the University of Toronto, specializing in health outcomes and evaluation. She has experience in conducting cost-effectiveness and budget impact analyses for both research and decision-making settings. She previously conducted economic analyses for the Ontario Health Technology Advisory Committee (OHTAC) and Vancouver Coastal Health. Her research interests include health technology assessment, health services outcomes and evaluation, health care priority setting and knowledge translation.</p>
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											<h2>Cheryl Pritlove</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Cheryl Pritlove, PhD, is a Clinical Research Specialist, employing qualitative methods to the study of a variety of health-related research topics, including cardiac health and diabetes. She has extensive experience and expertise in qualitative and arts-based methods, health policy, and psychosocial oncology. Cheryl has a BA in Health and Society and an MSc in Kinesiology and Health Science from York University. She conducted her doctoral research at the Princess Margaret Cancer Centre where she worked with patients as well as health care and service providers to identify gaps in the delivery of cancer care and explored innovative approaches to (acute/chronic) care integration.  She has conducted health services research with a number of organizations including Wellspring, ELLICSR Health, Wellness and Cancer Survivorship Centre, as well as the University of Toronto and York University.</p>
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											<h2>Rosane Nisenbaum</h2>
					<h3>Associate Scientist and Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Rosane Nisenbaum, PhD, has special interest in multi-level models, longitudinal and categorical data analysis and multiple imputation applied to neighborhood effects on mental health, and homelessness and housing studies. She provides assistance in the design and analysis of studies conducted by St. Michael’s investigators, fellows and students and is a member of St. Michael’s Research Ethics Board. Dr. Nisenbaum is an Assistant Professor in the Division of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, co-teaching the course ‘Laboratory in Statistical Design &amp; Analysis’ and serving as a Practicum supervisor.</p>
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											<h2>Althea Ambosta Logan</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p><span style="font-family: Calibri; font-size: medium;">Althea Ambosta Logan, M.A., CCRP, is a Data Management Specialist with the Research Information Systems team at the AHRC. Althea is responsible for reviewing data from multi-centre clinical trials and observational studies in Medidata RAVE and REDCap, with the goal of ensuring a high level of data quality. Althea is also involved in creating data management plans, performing validation activities on electronic case report forms and generating data management reports. Prior to her current role, Althea was a Clinical Research Specialist at the AHRC and was involved in the management and day-to-day operations of several multi-centre observational research studies. Althea holds a B.A. in Psychology from York University and an M.A. in Psychology (Brain and Cognitive Science Program) from the University of Manitoba. </span></p>
<p>&nbsp;</p>
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					<div style="display:none" id="observational-epidemiology-qualitative-research-kristin-mcbain-msc-ccrp">
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											<h2>Kristin McBain</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Kristin McBain, MSc, CCRP, PMP, has experience working in both academic and non-academic settings, and has been managing and conducting clinical research studies since 2010. She has been involved in all types of trials including bioequivalence, phase I-IV and observational research. Kristin’s clinical research experience is in the fields of neurology, oncology and pediatric critical care.</p>
<p>Kristin manages studies for both the Observational Epidemiology and Qualitative Research Unit and the Clinical Trials Unit. She is responsible for managing all aspects of each study from planning and start-up to study closure, including submitting Health Canada and ethics applications, managing stakeholders, training site coordinators, managing data and submitting progress reports to sponsors.</p>
<p>Kristin received a BSc in Biopharmaceutical Sciences, with a specialization in genomics, from the University of Ottawa and an MSc from Ryerson University, focusing on molecular imprinting of hydrogels as improved drug delivery vehicles. She is an author and co-author on several peer-reviewed abstracts and publications.</p>
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											<h2>Alana Harrington</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Alana Harrington obtained an MSc in Epidemiology from York University after she received her BSc (Hons.) from the University of Toronto with a double major in Biology and Biological Anthropology. She has been a St. Michael&#8217;s employee for over 15 years and has been involved in several different research areas including animal studies, randomized clinical trials, and observational projects that focused on improving the health of cardiac surgery patients. In her role as a Clinical Research Specialist, Alana is involved in the design, development and management of research projects in the Observational Epidemiology and Qualitative Research Unit.</p>
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											<h2>Gerald Lebovic</h2>
					<h3>Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Gerald Lebovic received an MSc in Statistics and a PhD in Biostatistics from the University of Toronto. He has 10 years of experience working on observational studies and has consulted on a variety of studies in the medical field. Currently, Gerald is a biostatistician at the HUB and an Assistant Professor at the Institute of Health Policy, Management and Evaluation at the University of Toronto. Gerald works with numerous researchers from various disciplines on a variety of observational studies. His research interests include health services research, longitudinal data analysis, observational studies and multi-state models.</p>
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											<h2>Karen Pope</h2>
					<h3>Manager, Observational Epidemiology and Qualitative Research Unit</h3>
					<h5></h5>
					<div class="bio">
						<p>Karen Pope, MSc, MA, CCRP, is the Manager of the Observational Epidemiology and Qualitative Research Unit of the AHRC. Karen has more than eight years of clinical research experience as well as extensive experience in basic science research, project management, and education. She is responsible for the oversight of observational and qualitative research studies as well as the planning and operations of patient registries.</p>
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											<h2>David Dai</h2>
					<h3>Biostatistician </h3>
					<h5></h5>
					<div class="bio">
						<p>David Dai received his MSc in Biostatistics and BSc (Hons.) in Pathobiology from the University of Toronto. In his current role at the AHRC, David provides statistical support for clinical trials and observational studies and analyzes data using R and SAS.</p>
<p>&nbsp;</p>
<p><span style="font-family: Calibri;"><span style="font-size: medium;"> </span></span></p>
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											<h2>Natalie Baker</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Natalie Baker, MSc, PhD(c), is a Clinical Research Specialist at the HUB focusing on qualitative research, health services and health equity. She works on interdisciplinary teams and has contributed to dozens of studies and initiatives from local to international. She is also a doctoral student at the School of Public Health at the University of Toronto, under the supervision of Katherine Boydell (University of Toronto, SickKids and Black Dog Institute) where she is focusing on creative approaches in youth mental health.</p>
<p>Natalie graduated with Great Distinction from McGill University with her BA in Psychology and Behavioural Sciences. She was a student in Donald Taylor&#8217;s Intergroup Relations and Aboriginal Peoples group where she conducted her final year project on understanding the impact of collective guilt using survey and implicit association lab testing techniques. She also completed a year-long advanced student field placement in a psychiatric ward and provided a creative outlet for children in treatment across Montreal hospitals. She went on to pursue political and critical psychology at the London School of Economics and was supervised by Derek Hook for her MSc dissertation in the Department of Social Psychology.</p>
<p>Natalie has been rooted in a creative learning environment and continues to be inspired by the arts as a powerful form of expression. She is involved in knowledge creation and dissemination strategies using the arts, media and community-based approaches, as well as being a co-author on traditional peer-reviewed publications and teaching in university and hospital settings.</p>
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											<h2>Clara Juando-Prats</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Clara Juando-Prats, PhD, MSc, BScN, is a Clinical Research Specialist at the AHRC. She completed her PhD at Faculty of Nursing in the University of Toronto, her MSc at the University of Edinburgh (UK), and the BScN at the Autonomous University of Barcelona (Spain). Clara uses visual methods and critical social theory to study access and utilization to the health care resources by vulnerable populations in Toronto. Her work with young mothers with low resources, young parents living in the margins, and in partnership with community agencies, aims to positively impact the physical and mental health of this population while giving them social connections with health care providers. Prior to joining the HUB, Clara was the leader of the Knowledge Translation and Nursing Research Unit at the Hospital Sant Pau in Barcelona, developing and evaluating projects studies related to clinical safety, knowledge translation, and nursing leadership. At the Hospital Sant Pau, Clara also worked as a nurse, a research nurse, and as an specialist in qualitative methods at the Epidemiology Department. She has been collaborating for several years with the Cochrane Collaboration and the Joanna Briggs Institute as an instructor and reviewer. During 2013 and 2012 she completed two fellowships, at the Spanish Ministry of Health in qualitative research with marginalized women, and at the Centre for Global Health at the University of Ottawa in Complex Interventions and Knowledge Mobilization. The focus of Clara’s work at the AHRC has been evaluation of complex interventions, qualitative and mixed methods designs for health research, knowledge translation and health inequities.</p>
<p>&nbsp;</p>
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											<h2>Allison Rau</h2>
					<h3>Clinical Study Assistant II</h3>
					<h5></h5>
					<div class="bio">
						<p><span style="color: #000000; font-family: Calibri; font-size: medium;"> <span style="color: #000000; font-family: Calibri; font-size: medium;">Allison Rau, MSc., is a Clinical Study Assistant with the Observational, Epidemiology and Qualitative Research Unit. She is responsible for coordinating and assisting multiple studies with patient enrolment, day-to-day site duties and study completion. Her past experience includes clinical research in pediatrics and geriatric psychiatry, particularly in the area of Alzheimer’s prevention in a population of clinically depressed and cognitively impaired seniors, where she has peer-authored several publications. Allison received her MSc. in Applied Clinical Pharmacology from the University of Toronto and her BSc. in Biological Sciences from the University of Calgary. </span></span></p>
<p>&nbsp;</p>
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											<h2>Roula Raptis</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Roula (Stavroula) Raptis, MSc, has a diverse research background and interests, lending well to her analytical skills and ability to work with multi-disciplinary teams. Roula completed her BSc at the University of Waterloo, with a focus in cell and molecular biology and microbiology. She went on to complete an MSc degree at the University of Toronto in the Department of Laboratory Medicine and Pathobiology. There she explored gene polymorphisms in cancer susceptibility genes and was a member of a large, nationally funded initiative &#8211; the interprovincial Colorectal Cancer Interdisciplinary Health Research Team. Roula has experience in both academic and nonacademic settings, including working for an independent analytical laboratory for several years, as well as in various teaching environments. In her current role with the Observational Epidemiology and Qualitative Research Unit, Roula is involved in study design, patient registry and database design, protocol and data collection form development, study planning and operations, and research communications. She is the author of a book chapter on genetic instability, and an author and co-author on several additional peer-reviewed publications.</p>
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											<h2>Kari Ala-Leppilampi</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Kari Ala-leppilampi received a Master of Planning (MPl) degree from Ryerson University’s School of Regional and Urban Planning and an MSc in Health Promotion from the Dalla Lana School of Public Health, University of Toronto. Through his graduate level training and employment in both urban planning and public health research, Kari brings a broad base of knowledge to his role at AHRC, and a uniquely valuable multidisciplinary perspective. While his specialty is qualitative inquiry, Kari is also well versed in quantitative and mixed methods approaches, and has taught courses on research theory and methods. His research has focused on a wide range of issues including outcomes associated with illicit drug policy, criminal justice diversion programs, mental health and addiction treatment services, and policies in relation to the provision of affordable and supportive housing. In keeping with his personal interest in physical activity, his research has also focused on the social benefits of active transportation, and the potential role of exercise and sport in recovery from mental health and addiction issues. As a Clinical Research Specialist, Kari focuses on qualitative, health services research by coordinating research studies, and conducting qualitative interviews and analysis on a range of health related interventions.</p>
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											<h2>Janet Parsons</h2>
					<h3>Scientist</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Janet Parsons, PhD, is a Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital with expertise in qualitative research methods. Dr. Parsons specializes in visual and narrative methods, and is engaged in a program of film-based research. Additional research interests include health equity, oncology, knowledge translation, and health services research. A physiotherapist, Dr. Parsons practiced for 18 years in acute-care teaching hospitals and is cross-appointed to the Department of Physical Therapy, University of Toronto.</p>
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											<h2>Christopher Allen</h2>
					<h3>Clinical Research Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Christopher Allen, BSc, has both clinical and basic research experience. He has a BSc (Hons.) in Biochemistry and Molecular Biology and his graduate work is in cancer immunology. He has more than three years of clinical research experience in hematology/oncology. As a Clinical Research Specialist in the Observational Epidemiology and Qualitative Research Unit, Christopher oversees several projects. His roles involve study design and initiation, site management, development of case report forms and databases, data collection and quality control, research communications, and site reimbursement.</p>
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					<div style="display:none" id="biostatistics-dr-gerald-lebovic-phd">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Gerald-1-220x220.jpg" alt="" />
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											<h2>Gerald Lebovic</h2>
					<h3>Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Gerald Lebovic received an MSc in Statistics and a PhD in Biostatistics from the University of Toronto. He has 10 years of experience working on observational studies and has consulted on a variety of studies in the medical field. Currently, Gerald is a biostatistician at the HUB and an Assistant Professor at the Institute of Health Policy, Management and Evaluation at the University of Toronto. Gerald works with numerous researchers from various disciplines on a variety of observational studies. His research interests include health services research, longitudinal data analysis, observational studies and multi-state models.</p>
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					<div style="display:none" id="biostatistics-prof-kevin-thorpe-mmath">
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											<h2>Kevin Thorpe</h2>
					<h3>Head of Biostatistics</h3>
					<h5></h5>
					<div class="bio">
						<p>Kevin Thorpe, MMath, has over 20 years of experience in clinical research as a biostatistician and methodologist. He is currently an Assistant Professor in the Dalla Lana School of Public Health at the University of Toronto and is Head of Biostatistics and a methodologist with the AHRC, where he specializes in clinical trials.</p>
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											<h2>Rosane Nisenbaum</h2>
					<h3>Associate Scientist and Biostatistician</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Rosane Nisenbaum, PhD, has special interest in multi-level models, longitudinal and categorical data analysis and multiple imputation applied to neighborhood effects on mental health, and homelessness and housing studies. She provides assistance in the design and analysis of studies conducted by St. Michael’s investigators, fellows and students and is a member of St. Michael’s Research Ethics Board. Dr. Nisenbaum is an Assistant Professor in the Division of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, co-teaching the course ‘Laboratory in Statistical Design &amp; Analysis’ and serving as a Practicum supervisor.</p>
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											<h2>David Dai</h2>
					<h3>Biostatistician </h3>
					<h5></h5>
					<div class="bio">
						<p>David Dai received his MSc in Biostatistics and BSc (Hons.) in Pathobiology from the University of Toronto. In his current role at the AHRC, David provides statistical support for clinical trials and observational studies and analyzes data using R and SAS.</p>
<p>&nbsp;</p>
<p><span style="font-family: Calibri;"><span style="font-size: medium;"> </span></span></p>
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											<h2>Amanda Francis</h2>
					<h3>Business Coordinator, AHRC</h3>
					<h5></h5>
					<div class="bio">
						<p>Amanda Francis has a BSc in Business Administration Human Resources Management from Wayne State University and over three years of Human Resource experience in various industries. As the Business Coordinator, Amanda looks after various employee inquiries, coordinates projects, manages internal websites, and assists with modifying Human Resources procedures within the office.</p>
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											<h2>Kim Phu</h2>
					<h3>Financial Consultant</h3>
					<h5></h5>
					<div class="bio">
						<p>Kim Phu, BA, CPA, CGA, has more than ten years of accounting experience, working in the areas of market research, structural engineering and for the not-for-profit sector. As the Financial Consultant at the AHRC, Kim is responsible for the day-to-day financial management of multi-million dollar project budgets and to support the Manager, Business Operations (AHRC) and others.</p>
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											<h2>Malini Handa Leno</h2>
					<h3>Manager of Business Operations, AHRC</h3>
					<h5></h5>
					<div class="bio">
						<p>Malini Handa Leno, MSc, MBA, PMP, is the Manager, Business Operations, and is accountable for financial, human resource, and contract management at the AHRC. Malini joined the AHRC with 15 years of experience in the pharmaceutical, CRO, and hospital sectors. Her previous roles have focused on clinical trial management, patient safety and risk management, and most recently, the implementation of information management systems to help transform health care. Malini holds an MBA from the Desautels Faculty of Management at McGill University, and an MSc in Pharmacology from Dalhousie University.</p>
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											<h2>Christopher Ducharme</h2>
					<h3>Manager, Research Informatics Systems</h3>
					<h5></h5>
					<div class="bio">
						<p>Chris Ducharme, MSc, BSc, is the Manager of the Research Information Systems unit at the AHRC. He manages core electronic data capture systems, which includes administration, programming and liaison with Information Technology. Chris has experience working in different software development and Information Technology support roles with the Ontario Government and as the Research Application Support Specialist with the AHRC. He holds an MSc in Computer Security from the University of Liverpool and a BSc in Computer Engineering from the University of Ottawa.</p>
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											<h2>Kosma Wysocki</h2>
					<h3>Research Applications Support Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Kosma Wysocki, B.Sc. Supports the AHRC’s applications through regular system and database administration and maintenance activities as well as performing custom development work as required. Kosma brings over five years of experience in technical support and systems administration experience to the AHRC.</p>
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											<h2>Maria Naydenova</h2>
					<h3>Senior Research Database Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Maria Naydenova, MD, has more than 15 years of clinical research experience and a strong clinical background. She received an MD in Plovdiv Medical University, Bulgaria. As a Research Database Specialist at the AHRC, Maria is responsible for the design, build, and support of clinical studies in various electronic data capture systems. Prior to joining the Research Information Systems team in 2010, Maria worked in pharmaceutical industries and health care sectors monitoring sites and overseeing clinical trial data for national and international clinical trials.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/no-photo-available-220x220.jpg" alt="" />
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											<h2>Bryan Boodhoo</h2>
					<h3>Research Database Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Bryan Boodhoo, MSc, has more than 20 years of clinical trials research experience, predominantly in the pharmaceutical industry. He works with the Research Information Systems team as an expert in Clinical Data Programming with thorough technical understanding in the design, setup and validation of databases, creating edit checks, data extraction and transformation, and generating formatted reports and listings using SAS, RAVE, Oracle Clinical or INFORM.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Danny-220x220.jpg" alt="" />
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											<h2>Danny Marchese</h2>
					<h3>Research Database Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Danny Marchese has been working with St. Michael’s Hospital since June of 2000, previously in the role of Technical Support Specialist, Information Technology. He has been working with the Research Information Systems team at the AHRC since June 2012 and is responsible for design and creation of electronic case report forms used for capturing clinical trial study data.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Pam-220x220.jpg" alt="" />
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											<h2>Pamela De Verno</h2>
					<h3>Senior Research Database Specialist </h3>
					<h5></h5>
					<div class="bio">
						<p>Pamela De Verno, MSc, has over 15 years of clinical research experience, as well as extensive experience in biotechnology research and development. As a Research Database Specialist with the Research Information Systems team, Pamela is responsible for the design, build and support of studies within a data management system for storage, validation and retrieval of clinical data.</p>
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											<h2>Alice Dang</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Alice Dang holds a BSc in Pharmaceutical Chemistry from the University of Toronto. She joined the AHRC in 2012 as a Professional Experiential Year (PEY) intern in the role of Research Assistant, and returned full-time as a Clinical Study Assistant after the completion of her degree in 2014. Now in the role of Research Data Management Specialist, Alice is responsible for reviewing the data of a large multi-centre trial to ensure it is complete and accurate, and also provides support to project managers in the Clinical Trials Unit.</p>
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											<h2>Brian Kirkham</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Brian Kirkham, MSc, joined the Research Information Systems team as a Research Data Management Specialist in June 2016. His role at the AHRC includes both database development and research data management. Brian received his BSc and MSc in Medical Physics from Ryerson University. Prior to joining the AHRC, Brian spent two years working with the research team at the St. Michael’s Hospital Head Injury Clinic.</p>
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					<div style="display:none" id="research-information-systems-srikanth-lingamaneni">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Srikanth-220x220.jpg" alt="" />
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											<h2>Srikanth Lingamaneni</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Srikanth Lingamaneni, BDS, PGDCR, has more than seven years of clinical data management experience.  He is responsible for the development of data management plans and data entry guidelines, providing training to site personnel on web-based electronic case report forms (eCRFs), performing testing and data validation activities on the eCRF, reviewing data to ensure it is complete and accurate, creating and running reports on data entry and validation progress, and supporting the clinical team with data management activities. Prior to joining the Research Information Systems team, Shrikanth worked for pharmaceutical and clinical research organizations as a data manager and study designer. He is a dentist from Rajiv Gandhi University of Health Sciences, Bangalore, India.</p>
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					<div style="display:none" id="research-information-systems-melissa-tom">
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Melissa-T-220x220.jpg" alt="" />
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											<h2>Melissa Tom</h2>
					<h3>SAS Programmer / Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Melissa Tom is a SAS Programmer and Research Data Management Specialist and has been with the Research Information Systems team since December 2012. In her role at the AHRC, she is responsible for data management, data extraction and reporting of clinical data. Melissa has several years of experience using SAS.</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2016/04/Jhansi-HUB-portraits-High-Res-29-of-75-220x220.jpg" alt="" />
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											<h2>Jhansi Lakshmi Saranu</h2>
					<h3>Research Data Management Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Jhansi Lakshmi Saranu, BDS, is a Certified Clinical Data Manager from the Society for Clinical Data Management with nine years of clinical data management experience. In the role of Research Data Management Specialist at the AHRC, Jhansi is responsible for development of data management plans, performing data validation activities on the electronic case report form, reviewing the data to ensure it is accurate and complete, and providing reports to sponsors and sites on validation progress. She works with the clinical team at the AHRC and also communicates with study research coordinators at sites and sponsors. Prior to joining the AHRC, Jhansi worked as a data coordinator at the Canadian Heart Research Centre, and is a dentist from NTR University of Health Sciences, India.</p>
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											<h2>Amr Sharaf</h2>
					<h3>Research Compliance and Education Specialist</h3>
					<h5></h5>
					<div class="bio">
						<p>Amr Sharaf, BSc, CCRP, has a background in biochemistry and over four years of experience performing monitoring and quality control of academic and industry-driven clinical trials. He previously worked at the Ottawa Hospital Research Institute as the institutional Clinical Research Monitor and Facilitator providing trial management and quality improvement support to over thirty clinical trials. In his role as a Research Compliance and Education Specialist, Amr provides monitoring services and guidance to clinical trial sites in addition to implementing educational initiatives aimed toward improving overall clinical trial conduct.</p>
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											<h2>Lisa Johnston</h2>
					<h3>Manager of Research Quality & Process</h3>
					<h5></h5>
					<div class="bio">
						<p>Lisa Johnston BScN, CCRP is the Manager of Research Quality &amp; Process.</p>
<p>Lisa has over 20 years in clinical research from coordinating Phase I drug and device trials to providing education, training and support to the clinical research community at both UHN and CAMH. Lisa also writes and revises GCP courses for CITICanada and CITIUSA.</p>
<p>Lisa is responsible for developing, implementing, monitoring, and maintaining procedures, processes, and guidelines relating to the clinical research activities of the AHRC.</p>
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											<h2>Andrea Tricco</h2>
					<h3>Scientist</h3>
					<h5></h5>
					<div class="bio">
						<p><span style="color: #000000; font-family: Arial; font-size: medium;">Andrea Tricco completed a MSc in Epidemiology (2002-2004) and a PhD in Population Health (2005-2009). She is a Scientist in the Knowledge Translation Program of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital (appointed Sept 2011) and directs the Knowledge Synthesis Team. She is an Associate Professor at the University of Toronto in the Dalla Lana School of Public Health (appointed June 2014). Her research interests are related to responding to decision-makers (including policy-makers, healthcare providers, and patients) through knowledge synthesis. Her research also focuses on advancing the science of knowledge synthesis and she is leading research projects related to rapid reviews, network meta-analysis, and scoping reviews.</span></p>
<p><span style="color: #000000; font-family: Arial; font-size: medium;">Dr. Tricco has published over 135 peer-reviewed articles. She currently holds a Tier 2 Canada Research Chair in Knowledge Synthesis and the Ontario Ministry of Research, Innovation, and Science Early Researcher Award. She is an Associate Editor for the Journal of Clinical Epidemiology, BMC Medical Research Methodology, and Systematic Reviews; and sits on the editorial board for the BMC Medicine. She developed an online systematic review course that &gt;335 students have completed, which is offered <span style="color: #000000; font-family: Arial; font-size: medium;">through the University of Toronto.</span></span></p>
<p><span style="color: #000000; font-family: Arial; font-size: medium;"> A sample of Dr. Tricco’s publications can be found <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=tricco+a"><u>here</u></a></span></p>
<p><span style="color: #000000; font-family: Arial; font-size: medium;"> </span></p>
<p>&nbsp;</p>
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			<img src="http://www.hubresearch.ca/wp-content/uploads/2014/09/Wai-Hin-Chan-220x220.jpg" alt="" />
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											<h2>Wai-Hin Chan</h2>
					<h3>Research Program Manager, Knowledge Translation Program</h3>
					<h5></h5>
					<div class="bio">
						<p>Wai-Hin Chan, MBA, PT, manages the business operations for BreaKThrough Knowledge Translation Services. She holds an MBA from Wilfrid Laurier University and a Bachelor of Science in Physical Therapy (PT) from the University of Toronto. She has 20 years of experience in health care, with a recent focus and dedication on administrating projects that focus on quality improvement in health care.</p>
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											<h2>Sharon Straus</h2>
					<h3>Director, Knowledge Translation Program</h3>
					<h5></h5>
					<div class="bio">
						<p>Dr. Sharon Straus, MD, FRCPC, MSc, HBSc, oversees all projects conducted by BreaKThrough in her capacity as the director of the Knowledge Translation Program. She is also a scientist and a geriatrician at St. Michael’s Hospital. Dr. Straus is a Professor in the Department of Medicine, and Division Director of Geriatric Medicine, both at the University of Toronto. She is the Co-Director of the Knowledge Translation Canada program as well as the Director of the Knowledge Translation Canada Strategic Training Initiative in Health Research program. She has more than 300 publications and is also the co-author of three textbooks including, ‘Evidence-based Medicine: How to practice and teach it’ and ‘Knowledge Translation in Health Care.’ The former has been published in nine languages and is currently in its fourth edition. It has been used in education curricula worldwide including undergraduate, postgraduate and continuing education courses. She holds a Tier 1 Canada Research Chair in Knowledge Translation and Quality of Care. Dr. Straus is an international leader in knowledge translation research and practice, a distinguished educator, and a skilled mentor.</p>
<p><strong>Featured Publications:</strong></p>
<ol>
<li>Tricco AC, Ashoor HM, Antony J, Beyene J, Veroniki AA, Isaranuwatchai W, Harrington A, Wilson C, Tsoursos S, Soobiah C, Yu CH, Hutton B, Hoch JS, Hemmelgarn BR, Moher D, Majumdar S, <strong>Straus SE</strong>. Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic review and network meta-analysis. BMJ. 2014 Oct. 1;349:g5459. <strong>Senior Responsible Author.</strong></li>
<li>Tricco AC, Antony J, Ivers NM, Ashoor HM, Khan PA, Blondal E, Ghassemi M, MacDonald H, Chen MH, Ezer LK, <strong>Straus SE</strong>. Effectiveness of quality improvement strategies for coordination of care to reduce use of health care services: a systematic review and meta-analysis. CMAJ. 2014 Sep. [Epub ahead of print]. <strong>Senior Responsible Author.</strong></li>
<li>Wilcox E, Chong C, Stanbrook M, Tricco AC, Wong C, <strong>Straus SE</strong>. Does This Patient Have An Exudative Pleural Effusion? How Do I Perform A Thoracentesis And Analyze The Results. JAMA. 2014 Jun. ;311(23):2422-2431. <strong>Senior Responsible Author.</strong></li>
<li>Kwan E, <strong>Straus SE</strong>. Assessment and Management of Falls in Older People. CMAJ. 2014 Jun. 30 [Epub ahead of print] (Trainee publication). <strong>Senior Responsible Author.</strong></li>
<li>Stelfox HT, Cameron P, Fortin MC, Francescutti L, Kenneth J, Kmetik K, Kortbeek J, Nathens A, Phan N, Singleton B, Travers A, Zygun D, Noseworthy T, <strong>Straus SE</strong>. Development and Evaluation of Evidence-Informed Quality Indicators for Adult Injury Care. Ann Surg. 2013 May 7 [Epub ahead of print]. <strong>Senior Responsible Author.</strong></li>
<li>Brouwers M, Thabane L, Moher D, <strong>Straus SE</strong>. Comparative Effectiveness Research Paradigm: Implications for Systematic Reviews and Clinical Practice Guidelines. J Clin Oncol. 2012 Dec 1; 30(34): 4202-4207. <strong>Senior Responsible Author.</strong></li>
<li>Yu Ch, Bahniwal R, Laupacis A, Leung E, Orr MS, <strong>Straus SE</strong>. Systematic review and evaluation of web-accessible tools for management of diabetes and related cardiovascular risk factors by patients and healthcare providers. J AM Med Inform Assoc. 2012 Jul-Aug;19(4):514-22. <strong>Senior Responsible</strong> <strong>Author.</strong></li>
<li>Wong C, Holroyd-Leduc J, Simel DL, <strong>Straus SE</strong>. Does this patient have delirium? Value of bedside instruments. JAMA 2010 Aug 18;304(7):779-86. <strong>Senior Responsible Author.</strong></li>
<li>Sambunjak D, <strong>Straus SE</strong>, Marusic A. Mentoring in academic medicine: A systematic review. JAMA 2006;296(9):1103-15. <strong>Senior Responsible Author</strong>.</li>
<li>Holroyd-Leduc J, <strong>Straus SE</strong>. Management of urinary incontinence in women:  Systematic review. JAMA 2004;291(8):986-95. (Trainee publication, Mentor to Dr. Holroyd-Leduc). <strong>Senior Responsible Author</strong>.</li>
<li>Holroyd-Leduc J, <strong>Straus SE</strong>. Management of urinary incontinence in women:  Clinical applications. JAMA 2004;291(8):996-9. (Trainee publication, Mentor to Dr. Holroyd-Leduc). <strong>Senior Responsible Author</strong>.</li>
<li><strong>Straus SE</strong>, Green M, Bell DS, Badgett R, Davis D, Gerrity M, Ortiz E, Shaneyfelt TM, Whelan C, Mangrulkar R, on behalf of the SGIM EBM Task Force. Evaluating the teaching of evidence based medicine: conceptual framework. BMJ 2004;329(7473):1029-1032. <strong>Principal Author</strong>.</li>
</ol>
<p>To view more of Dr. Straus&#8217;s publications, go to <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=Sharon+Straus" target="_blank">PubMed</a>.</p>
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